Multifunctional and Sprayable 2D MoS2/Silk Sericin Bio-Nanocomposite Dressings with Enhanced Photothermal Effect for Infected Wound Healing

Advanced Fiber Materials, Год журнала: 2024, Номер 6(4), С. 1074 - 1091

Опубликована: Апрель 15, 2024

Язык: Английский

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Monomer Trapping Synthesis Toward Dynamic Nanoconfinement Self‐healing Eutectogels for Strain Sensing

Advanced Science, Год журнала: 2024, Номер 11(42)

Опубликована: Сен. 16, 2024

Abstract The rapid advancement in attractive platforms such as biomedicine and human‐machine interaction has generated urgent demands for intelligent materials with high strength, flexibility, self‐healing capabilities. However, existing ability are challenged by a trade‐off between low elastic modulus, healing due to the inherent strength of noncovalent bonding. Here, drawing inspiration from human fibroblasts, monomer trapping synthesis strategy is presented based on dissociation reconfiguration amphiphilic ionic restrictors (7000‐times volume trapping) develop eutectogel. Benefiting nanoconfinement dynamic interfacial interactions, molecular chain backbone formed confined domains mechanically reinforced while preserving soft movement resulting eutectogels demonstrate superior mechanical properties (1799% 2753% higher tensile toughness than pure polymerized deep eutectic solvent), excellent efficiency (>90%), tangential modulus (0.367 MPa during working stage), sensitively monitor activities. This poised offer new perspective developing wearable electronics tailored body motion.

Язык: Английский

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Advancements and Challenges in Self-Healing Hydrogels for Wound Care

Gels, Год журнала: 2024, Номер 10(4), С. 241 - 241

Опубликована: Апрель 1, 2024

This manuscript explores self-healing hydrogels as innovative solutions for diverse wound management challenges. Addressing antibiotic resistance and tailored care, these exhibit promising outcomes, including accelerated closure tissue regeneration. Advancements in multifunctional with controlled drug release, antimicrobial properties, real-time assessment capabilities signal a significant leap toward patient-centered treatments. However, challenges such scalability, long-term safety evaluation, variability clinical outcomes persist. Future directions emphasize personalized medicine, manufacturing innovation, rigorous evaluation through trials, interdisciplinary collaboration. features the ongoing pursuit of effective, adaptable, comprehensive care to transform medical treatments improve patient outcomes.

Язык: Английский

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Biodegradable underwater tissue adhesive enabled by dynamic poly(thioctic acid) network

Chemical Engineering Journal, Год журнала: 2024, Номер 489, С. 151352 - 151352

Опубликована: Апрель 16, 2024

Язык: Английский

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pH-responsive bioadhesive with robust and stable wet adhesion for gastric ulcer healing

Biomaterials, Год журнала: 2024, Номер 309, С. 122599 - 122599

Опубликована: Апрель 30, 2024

Язык: Английский

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A mussel inspired polyvinyl alcohol/collagen/tannic acid bioadhesive for wet adhesion and hemostasis

Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 235, С. 113766 - 113766

Опубликована: Янв. 23, 2024

Язык: Английский

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The study of double-network carboxymethyl chitosan/sodium alginate based cryogels for rapid hemostasis in noncompressible hemorrhage

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 266, С. 131399 - 131399

Опубликована: Апрель 18, 2024

Язык: Английский

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Growth Factors-Loaded Temperature-Sensitive Hydrogel as Biomimetic Mucus Attenuated Murine Ulcerative Colitis via Repairing the Mucosal Barriers

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(6), С. 7686 - 7699

Опубликована: Янв. 30, 2024

The pathogenesis of ulcerative colitis (UC) is associated with the shedding gut mucus. Herein, inspired by biological functions mucus, growth factors-loaded in situ hydrogel (PHE-EK) was designed for UC treatment integrating dihydrocaffeic acid-modified poloxamer as a thermosensitive material hyaluronic acid (colitis-specific adhesive), epigallocatechin-3-gallate (antibacterial agent), and bioactive factors (KPV tripeptide epidermal factor). PHE-EK presented good properties, flowable liquid at room temperature gelled within 10 s when exposed to body temperature. mechanical strength strain 77.8%. Moreover, displayed antibacterial activity against Escherichia coli. Importantly, vitro vivo adhesive tests showed that could specifically adhere inflamed colon via electrostatic interaction. When biomimetic mucus rectally administrated rats, it effectively hindered weight loss, reduced disease index improved colonic shorting. expression pro-inflammatory cytokines (e.g., IL-1β, IL-6, TNF-α) laminae propria or epitheliums rats substantially inhibited PHE-EK. Besides, were well rearranged, tight junction proteins (Zonula-1 Claudin-5) between them greatly upregulated after treatment. Collectively, might be promising therapy UC.

Язык: Английский

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3D Printing Silk Fibroin/Polyacrylamide Triple-Network Composite Hydrogels with Stretchability, Conductivity, and Strain-Sensing Ability as Bionic Electronic Skins

ACS Biomaterials Science & Engineering, Год журнала: 2024, Номер 10(5), С. 3489 - 3499

Опубликована: Апрель 25, 2024

Electronic skins have received increasing attention due to their great application potential in wearable electronics. Meanwhile, tremendous efforts are still needed for the fabrication of multifunctional composite hydrogels with complex structures electronic via simple methods. In this work, a novel three-dimensional (3D) printing hydrogel stretchability, conductivity, and strain-sensing ability is produced using one-step photocuring method achieve dual-signal response skin. The exhibits triple-network structure composed silk microfibers (SMF), regenerated fibroin (RSF), polyacrylamide (PAM). establishment triple networks based on electrostatic interaction between SMF RSF, as well chemically cross-linked RSF PAM. Thanks its specific components, possesses enhanced mechanical properties (elastic modulus 140 kPa, compressive stress 21 MPa, compression 600 kPa) 3D printability while retaining stretchability flexibility. negatively charged cations phosphate-buffered saline endows good conductivity after immersion low-concentration (10 mM) salt solution. Moreover, scaffold successfully realizes real-time monitoring. Therefore, proposed hydrogel-based ionic sensor promising skin tissue engineering, monitoring, soft robotics, human-machine interfaces.

Язык: Английский

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A Simple Physical Kneading Strategy to Prepare an Ultrahigh-Stretchable Conductive Starch/Poly(vinyl alcohol)/Borax/Carbon Nanotube Hydrogel for Flexible Capacitive Electronics

ACS Applied Polymer Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

Язык: Английский

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