ACS Biomaterials Science & Engineering,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 1, 2024
Because
of
their
unique
electromechanical
coupling
response,
piezoelectric
smart
biomaterials
demonstrated
distinctive
capability
toward
effective,
efficient,
and
quick
diagnosis
treatment
a
wide
range
diseases.
Such
materials
have
potentiality
to
be
utilized
as
wireless
therapeutic
methods
with
ultrasonic
stimulation,
which
can
used
self-powered
biomedical
devices.
An
emerging
advancement
in
the
realm
personalized
healthcare
involves
utilization
biosensors
for
such
diverse
physiological
signals
human
body,
viruses,
pathogens,
diseases
like
neurodegenerative
ones,
cancer,
etc.
The
combination
nanoparticles
ultrasound
has
been
established
promising
approach
sonodynamic
therapy
piezocatalytic
therapeutics
provides
appealing
alternatives
noninvasive
treatments
chronic
wounds,
neurological
diseases,
Innovations
implantable
medical
devices
(IMDs),
energy
generator
(iPEG),
offer
significant
advantages
improving
functioning
ability
power
cardiac
pacemaker
restore
heart
function.
This
comprehensive
review
critically
evaluates
role
piezoelectricity
disease
treatment,
highlighting
implication
It
also
discusses
potential
monitoring,
tissue
engineering,
other
applications
while
emphasizing
future
trends
challenges
field.
Journal of Materials Chemistry A,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
This
review
examines
the
integration
of
artificial
intelligence
with
nanogenerators
to
develop
self-powered,
adaptive
systems
for
applications
in
robotics,
wearables,
and
environmental
monitoring.
Abstract
Infected
bone
defects
are
a
growing
global
health
issue,
with
risks
including
destruction,
disability,
and
even
death.
The
main
clinical
challenge
is
the
difficulty
in
simultaneously
achieving
effective
antibacterial
action
promoting
regeneration.
Calcination
at
800°C
induces
phase
transition
from
cubic
(C‐BSTO)
to
polarized
tetragonal
(T‐BSTO),
imparting
piezoelectric
properties.
Subsequent
treatment
sodium
borohydride
generates
oxygen
vacancies,
enhancing
polarization
performance.
synthesized
T‐BSTO‐V
o
achieves
99.83%
efficiency
against
methicillin‐resistant
Staphylococcus
aureus
(MRSA)
under
1.5
W
cm²
ultrasound
(US)
irradiation
for
20
min.
Mild
US
activates
signal,
Schwann
cell
(SC)
neurogenic
differentiation
via
PI3K‐AKT
signaling
intracellular
Ca²⁺
elevation.
Further
studies
showed
that
synergy
of
neurotransmitter
SCs
electric
signal
increased
osteogenic
human
marrow
mesenchymal
stem
cells
(BMSCs).
Consequently,
US‐irradiated
effectively
promotes
innervated
regeneration
MRSA‐infected
defect
model
through
rapidly
killing
bacteria,
modulating
immune
microenvironment.
This
study
offers
new
approach
developing
bioactive
sonosensitizers
phase/defect
engineering,
treats
enhanced
piezocatalytic
effect
Bone
is
a
dynamic
tissue
reshaped
by
constant
bone
formation
and
resorption
to
maintain
its
function.
The
skeletal
system
accounts
for
approximately
70%
of
the
total
volume
body,
continuous
remodeling
requires
quantities
energy
material
consumption.
Adipose
main
storehouse
body
has
strong
adaptive
capacity
participate
in
regulation
various
physiological
processes.
Considering
that
obesity
metabolic
syndrome
have
become
major
public
health
challenges,
while
osteoporosis
osteoporotic
fractures
other
problems
aging
population,
it
would
be
interesting
explore
these
2
diseases
together.
Currently,
an
increasing
number
researchers
are
focusing
on
interactions
between
multiple
systems,
i.e.,
organs
tissues
functionally
coordinated
together
pathologically
interact
with
each
body.
However,
there
lack
detailed
reviews
summarizing
effects
lipid
metabolism
homeostasis
adipose
tissue.
This
review
provides
summary
recent
advances
understanding
how
molecules
adipose-derived
hormones
affect
homeostasis,
tissue,
as
organ,
affects
metabolism,
regulated
bone-derived
cytokines.
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 8309 - 8336
Опубликована: Авг. 1, 2024
The
treatment
of
craniofacial
bone
defects
caused
by
trauma,
tumors,
and
infectious
degenerative
diseases
is
a
significant
issue
in
current
clinical
practice.
Following
the
rapid
development
tissue
engineering
(BTE)
last
decade,
bioactive
scaffolds
coupled
with
multifunctional
properties
are
high
demand
regard
to
effective
therapy
for
defects.
Herein,
an
innovative
scaffold
consisting
GO/Cu
nanoderivatives
GelMA-based
organic-inorganic
hybrids
was
reported
repairing
full-thickness
calvarial
defect.
