Nutrition Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 2, 2024
Abstract
Time-restricted
feeding
(TRF)
is
a
lifestyle
intervention
that
aims
to
maintain
consistent
daily
cycle
of
and
fasting
support
robust
circadian
rhythms.
Recently,
it
has
gained
scientific,
medical,
public
attention
due
its
potential
enhance
body
composition,
extend
lifespan,
improve
overall
health,
as
well
induce
autophagy
alleviate
symptoms
diseases
like
cardiovascular
diseases,
type
2
diabetes,
neurodegenerative
cancer,
ischemic
injury.
However,
there
still
considerable
debate
on
the
primary
factors
contribute
health
benefits
TRF.
Despite
not
imposing
strict
limitations
calorie
intake,
TRF
consistently
led
reductions
in
intake.
Therefore,
while
some
studies
suggest
are
primarily
caloric
restriction
(CR),
others
argue
key
advantages
arise
only
from
CR
but
also
duration
fasting,
timing
period,
alignment
with
To
elucidate
roles
mechanisms
beyond
CR,
this
review
incorporates
did
use
equivalent
energy
intake
which
addresses
previous
lack
comprehensive
research
without
provides
framework
for
future
directions.
Nutrients,
Год журнала:
2022,
Номер
14(13), С. 2569 - 2569
Опубликована: Июнь 21, 2022
The
metabolic
benefits
of
time-restricted
eating
(TRE)
in
humans
are
statistically
significant
but
not
clinically
relevant.
Few
data
available
about
the
effects
TRE
on
gut
microbiota.
We
compared
a
regimen
(<12
h
feeding;
n
=
25)
with
time-unrestricted
(TUE)
(>12
24),
clinical
and
dietary
variables
gut-microbiota
composition
patients
obesity,
who
were
subjected
for
12
weeks
to
same
caloric
restriction.
Median
weight
loss
was
4.0
kg
2.2
TUE
groups,
respectively,
between-group
borderline
difference
(p
0.049).
No
found
other
dietary,
anthropometric,
or
laboratory
variables.
There
no
substantial
differences
alpha
beta
diversity
composition.
group
showed
increase
frequency
Lachnospiraceae,
Parasutterella,
Romboutsia
at
study’s
end.
A
induced
small
changes
both
metabolic/dietary
composition,
respect
TUE.
microbial
we
have
uncertain
significance.
Cancer and Metastasis Reviews,
Год журнала:
2022,
Номер
41(3), С. 697 - 717
Опубликована: Авг. 19, 2022
Obesity
and
the
associated
metabolic
syndrome
is
considered
a
pandemic
whose
prevalence
steadily
increasing
in
many
countries
worldwide.
It
complex,
dynamic,
multifactorial
disorder
that
presages
development
of
several
metabolic,
cardiovascular,
neurodegenerative
diseases,
increases
risk
cancer.
In
patients
with
newly
diagnosed
cancer,
obesity
worsens
prognosis,
recurrence
decreasing
survival.
The
multiple
negative
effects
on
cancer
outcomes
are
substantial,
great
clinical
importance.
Strategies
for
weight
control
have
potential
utility
both
prevention
efforts
enhancing
outcomes.
Presently,
time-restricted
eating
(TRE)
popular
dietary
intervention
involves
limiting
consumption
calories
to
specific
window
time
without
any
proscribed
caloric
restriction
or
alteration
composition.
As
such,
TRE
sustainable
long-term
behavioral
modification,
when
compared
other
interventions,
has
shown
health
benefits
animals
humans.
preliminary
data
regarding
feeding
growth
animal
models
promising
but
studies
humans
lacking.
Interestingly,
short-term
randomized
trials
favorable
reduce
factors;
however,
yet
investigate
reductions
incidence
general
population.
Few
been
conducted
populations,
number
underway
examine
effect
biology
recurrence.
Given
simplicity,
feasibility,
improvements
elicited
by
obese
men
women,
may
be
useful
survivors;
implementation
setting
will
require
greater
in-depth
investigation.
Obesity,
Год журнала:
2024,
Номер
32(4), С. 640 - 654
Опубликована: Фев. 21, 2024
Abstract
Objective
A
growing
body
of
evidence
has
supported
the
health
benefits
extended
daily
fasting,
known
as
time‐restricted
eating
(TRE);
however,
whether
addition
TRE
enhances
calorie
restriction
(CR)
remains
unclear.
Methods
PubMed,
Scopus,
Cochrane
Library,
and
Google
Scholar
were
searched
through
April
2023.
This
systematic
review
includes
randomized
controlled
trials
(RCTs)
that
compared
CR
+
with
alone
in
energy‐matched
conditions
at
least
8
weeks
duration
assessed
changes
weight
cardiometabolic
disease
risk
factors
adults
overweight
and/or
obesity.
Results
Seven
studies
identified
(
n
=
579).
Two
reported
greater
loss
reductions
diastolic
blood
pressure
after
to
14
weeks,
whereas
one
study
improvements
triglycerides
glucose
tolerance
(3
days/week)
following
26
weeks.
One
significant
increases
homeostatic
model
assessment
insulin
resistance
(HOMA‐IR)
levels
versus
There
no
statistically
differences
any
other
outcome
variable
between
two
interventions.
Conclusions
The
regimens
resulted
some
studies;
majority
did
not
find
additional
benefits.
Nutrition Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 2, 2024
Abstract
Time-restricted
feeding
(TRF)
is
a
lifestyle
intervention
that
aims
to
maintain
consistent
daily
cycle
of
and
fasting
support
robust
circadian
rhythms.
Recently,
it
has
gained
scientific,
medical,
public
attention
due
its
potential
enhance
body
composition,
extend
lifespan,
improve
overall
health,
as
well
induce
autophagy
alleviate
symptoms
diseases
like
cardiovascular
diseases,
type
2
diabetes,
neurodegenerative
cancer,
ischemic
injury.
However,
there
still
considerable
debate
on
the
primary
factors
contribute
health
benefits
TRF.
Despite
not
imposing
strict
limitations
calorie
intake,
TRF
consistently
led
reductions
in
intake.
Therefore,
while
some
studies
suggest
are
primarily
caloric
restriction
(CR),
others
argue
key
advantages
arise
only
from
CR
but
also
duration
fasting,
timing
period,
alignment
with
To
elucidate
roles
mechanisms
beyond
CR,
this
review
incorporates
did
use
equivalent
energy
intake
which
addresses
previous
lack
comprehensive
research
without
provides
framework
for
future
directions.