Acta Psychologica, Год журнала: 2025, Номер 257, С. 105068 - 105068
Опубликована: Май 16, 2025
Язык: Английский
Clinical Nutrition, Год журнала: 2022, Номер 41(10), С. 2244 - 2263
Опубликована: Авг. 7, 2022
Low muscle mass and malnutrition are prevalent conditions among adults of all ages, with any body weight or index, acute chronic conditions, including COVID-19. This article synthesizes the latest research advancements in health malnutrition, their impact on immune function, clinical outcomes. We provide a toolkit illustrations scientific information that healthcare professionals can use for knowledge translation, educating patients about importance identifying treating low malnutrition. focus emerging evidence mitochondrial dysfunction context aging disease, as well cross-talk between skeletal system. address myosteatosis component composition, discuss direct, indirect surrogate assessments ultrasound, computerized tomography, deuterated creatine dilution, calf circumference. Assessments function also included (handgrip strength, physical performance tests). Finally, we nutrition interventions to support anabolism, reduce catabolism, improve patient These include protein amino acids, branched-chain leucine; β-hydroxy-β-methylbutyrate (HMB), vitamin D; n-3 polyunsaturated fatty acids (n-3 PUFA), polyphenols, oral nutritional supplements. concluded recommendations practice call action focusing evaluating composition targeted interventions, consequently ability
Язык: Английский
Процитировано
106
JAMA Network Open, Год журнала: 2025, Номер 8(2), С. e2457859 - e2457859
Опубликована: Фев. 4, 2025
Importance Cancer and its treatment negatively impact the mental health of older adults. The potential exercise interventions as a complementary to alleviate psychological impacts cancer is promising, but there are gaps in current literature. Objective To determine if associated with improvements outcomes among adults cancer. Data Sources PubMed, Embase, PsycINFO, Cochrane databases were searched from database inception November 5, 2024. Search terms used geriatrics , depression anxiety quality life . Study Selection English-language randomized clinical trials (RCTs) that analyzed association various at least 1 3 (depression, anxiety, or health-related quality-of-life [HRQOL]) included. control groups given usual care. Studies included mean age participants was than 60 years had diagnosis any regardless comorbidities. Extraction Synthesis screened, data extracted by 2 independent authors. Random-effects meta-analyses meta-regressions for analysis. Preferred Reporting Items Systematic Reviews Meta-Analyses guideline followed. Main Outcomes Measures primary depression, HRQOL. Standardized difference (SMD) quantify outcomes. Results A total 27 RCTs 1929 Meta-analyses observed an significant reduction levels (SMD = −0.53; 95% CI, −0.79 −0.28) −0.39; −0.66 −0.12) overall HRQOL 0.63; 0.10 1.17). Subgroup analyses revealed mind-body significantly improved −0.89; −1.51 −0.27) −0.77; −1.54 −0.01) compared conventional interventions. Conclusion In this systematic review meta-analysis RCTs, found be reduced These findings suggest care professionals policymakers should focus more on implementing improve vulnerable population.
Язык: Английский
Процитировано
4
EClinicalMedicine, Год журнала: 2023, Номер 59, С. 101937 - 101937
Опубликована: Апрель 6, 2023
Exercise is recommended for people with cancer. The aim of this study was to evaluate the harms exercise in patients cancer undergoing systemic treatment.
Язык: Английский
Процитировано
36
International Journal of COPD, Год журнала: 2023, Номер Volume 18, С. 1251 - 1266
Опубликована: Июнь 1, 2023
Chronic respiratory diseases (CRD), is a group of disorders, primarily chronic obstructive pulmonary disease and asthma, which are characterized by high prevalence disability, recurrent acute exacerbations, multiple comorbidities, resulting in exercise limitations reduced health-related quality life. Exercise training, an important tool rehabilitation, reduces adverse symptoms patients relieving limitations, increasing gas exchange, central peripheral hemodynamic forces, enhancing skeletal muscle function. Aerobic, resistance, high-intensity intermittent exercises, other emerging forms such as aquatic Tai Chi effectively improve capacity, physical fitness, function with CRD. The underlying mechanisms include enhancement the body's immune response, better control inflammatory acceleration interaction between vagus sympathetic nerves to exchange. Here, we reviewed new evidence benefits intervention rehabilitation disease, bronchial bronchiectasis, interstitial lung cancer.
Язык: Английский
Процитировано
27
BMC Palliative Care, Год журнала: 2022, Номер 21(1)
Опубликована: Май 17, 2022
Cachexia is a prevalent muscle wasting syndrome among people with advanced cancer that profoundly impacts patient quality of life (QoL) and physical function. Exercise can improve QoL, function, overall health in may be an important addition to treatment approaches for cachexia. Greater understanding patients' perception exercise help elucidate the feasibility implementing interventions cachexia facilitate design patient-centered interventions. We aimed describe patients cachexia, capture motivators, barriers, preferences, inform Individual interviews (n = 20) locally or metastatic were conducted analyzed using reflexive thematic analysis. Main themes from were: 1) Life disrupted by cachexia; 2) offers hope; 3) barriers are multifaceted; 4) access support important. Participants reported their had intensely altered lives, including ability exercise. was perceived as participants described hope wellbeing. Yet, several complex such burdensome symptoms overwhelming impact COVID-19 pandemic, hindered participation prevented fully realizing benefits Factors believed engagement overcome included increased (e.g., professional supervision) accessibility convenient locations). Patient-reported preferences interventions, particularly within future research studies aiming establish efficacy
Язык: Английский
Процитировано
29
Cancers, Год журнала: 2023, Номер 15(6), С. 1671 - 1671
Опубликована: Март 8, 2023
Due to the aging of population, in 70% cases, a new cancer diagnosis equals geriatric patient. In this beyond concept mortality and morbidity, functional capacity, disability, quality life remain crucial. fact, when status is preserved, pathogenetic curve towards disability will stop or even regress. The present systematic review investigated effectiveness physical exercise, as part holistic assessment patient, for preventing improving patient’s life, partially reducing all-cause mortality. This evidence must point decentralization care by implementing development rehabilitation programs elderly patients either before after anti-cancer therapy.
Язык: Английский
Процитировано
16
Cancers, Год журнала: 2022, Номер 14(2), С. 342 - 342
Опубликована: Янв. 11, 2022
Cachexia is a multifactorial syndrome that presents with, among other characteristics, progressive loss of muscle mass and anti-cardiac remodeling effect may lead to heart failure. This condition affects about 80% patients with advanced cancer contributes worsening patients' tolerance anticancer treatments their premature death. Its pathogenesis involves an imbalance in metabolic homeostasis, increased catabolism inflammatory cytokines levels, leading proteolysis lipolysis, insufficient food intake. A multimodal approach indicated for cachexia, the aim reducing speed wasting improving quality life, which include nutritional, physical, pharmacologic, psychological support. review aims outline mechanisms loss, as well evaluate current clinical evidence use physical exercise cachexia.
Язык: Английский
Процитировано
23
Journal of Cancer Survivorship, Год журнала: 2023, Номер 18(5), С. 1548 - 1556
Опубликована: Июнь 2, 2023
Язык: Английский
Процитировано
13
BMC Palliative Care, Год журнала: 2024, Номер 23(1)
Опубликована: Июнь 20, 2024
Abstract Objective Explore the feasibility of a mobile health(mHealth) and virtual reality (VR) based nutrition-exercise-psychology integrated rehabilitation model in Chinese cancer patients. Methods We recruited patients Oncology department Affiliated Changzhou No. 2 People’s Hospital Nanjing Medical University from October 2022 to April 2023. The program was provided by team medical oncologists, dietitians, psychotherapists, oncology specialist nurses. Participants received standard anti-cancer therapy intervention including hospitalized group-based exercise classes, at-home physical activity prescription, behavior change education, oral nutrition supplements, psychological counseling. An effective course includes two consecutive hospitalization periods home-based (8 weeks). Access as well changes aspects physical, nutritional, status. Results At cutoff date 2023, recruitment rate 75% (123/165). 11.4%patients were lost follow-up, 3.25% withdrew halfway. Respectively, completion nutrition, exercise, psychology 85%,55%, 63%. Nutrition interventions show highest compliance. parameters psychology, muscle mass, quality life after showed significant improvements ( P < .05). There no statistical difference > .05) handgrip strength 6-minute walking speed. Conclusion It is feasible conduct mHealth VR-based A larger multi-center trial warranted future. Trial registration ChiCTR2200065748 Registered 14 November 2022.
Язык: Английский
Процитировано
5
United European Gastroenterology Journal, Год журнала: 2023, Номер 11(10), С. 998 - 1009
Опубликована: Ноя. 21, 2023
Abstract Background Parameters to adapt individual treatment strategies for patients with pancreatic ductal adenocarcinoma (PDAC) are urgently needed. The present study aimed evaluate body composition parameters as predictors of overall survival (OS) in PDAC patients. Methods Measurements were performed on computed tomography scans at diagnosis. Height‐standardized and Body Mass Index‐ sex‐adjusted regression formulas deriving cut‐offs from a healthy population used. Kaplan‐Meier method the log‐rank test was analysis. Independent prognostic factors identified uni‐ multivariable Cox analyses. Results In total, 354 analyzed. model, besides tumor stage resection status, only myosteatosis (HR 1.53; 95% CI 1.10–2.14, p = 0.01) an independent factor OS among parameters. Subgroup analyses revealed that impact higher ≤68 years age, advanced stages without curative intended resection. Conclusions analysis one largest Caucasian cohorts date, demonstrated be PDAC. To improve outcomes, prospective trials aiming investigate utility early assessment subsequent intervention by dieticians, sports medicine physicians, physiotherapists warranted.
Язык: Английский
Процитировано
10