Bioresource Technology, Год журнала: 2024, Номер unknown, С. 131837 - 131837
Опубликована: Ноя. 1, 2024
Язык: Английский
The Scientific World JOURNAL, Год журнала: 2022, Номер 2022, С. 1 - 15
Опубликована: Март 11, 2022
The utilization of microbial pectinase in different industries has been increased its world demand. major sources are microorganisms mainly bacteria, fungi and yeast. low-cost agro-industrial wastes as substrates preferable production. Pectinase production faced various parameters optimization constraints such temperature, pH times which the main factors enzyme is getting attention due to several advantages; hence, it needs be explored further take maximum advantage industries. This review discusses pectin substance structure, substrate for production, influencing industrial application also challenges future opportunities applying industry.
Язык: Английский
Процитировано
116
Materials Today Bio, Год журнала: 2023, Номер 19, С. 100560 - 100560
Опубликована: Янв. 21, 2023
Filamentous fungi drive carbon and nutrient cycling across our global ecosystems, through its interactions with growing decaying flora their constituent microbiomes. The remarkable metabolic diversity, secretion ability, fiber-like mycelial structure that have evolved in filamentous been increasingly exploited commercial operations. industrial potential of fermentation ranges from the discovery bioproduction enzymes bioactive compounds, decarbonization food material production, to environmental remediation enhanced agricultural production. Despite fundamental impact ecology biotechnology, molds mushrooms not, to-date, significantly intersected synthetic biology ways comparable other cell factories (e.g. Escherichia coli,Saccharomyces cerevisiae, Komagataella phaffii). In this review, we summarize a suite computational tools for mining, engineering optimization as chassis. A combination methods genetic engineering, mutagenesis, experimental evolution, modeling can be used address strain development bottlenecks established emerging industries. These include slow mycelium growth rate, low production yields, non-optimal alternative feedstocks, difficulties downstream purification. scope biomanufacturing, then detail previous efforts improving key by targeting protein processing pathways, hyphae morphogenesis, transcriptional control. Bringing practices into hidden world will serve expand limited panel host organisms allow commercially-feasible environmentally-sustainable enzymes, chemicals, therapeutics, foods, materials future.
Язык: Английский
Процитировано
46
Bioresource Technology, Год журнала: 2021, Номер 326, С. 124771 - 124771
Опубликована: Янв. 30, 2021
Язык: Английский
Процитировано
57
Annual Review of Food Science and Technology, Год журнала: 2023, Номер 15(1), С. 173 - 187
Опубликована: Дек. 22, 2023
Animal-based agriculture and the production of protein-rich foods from animals, particularly ruminants, are not sustainable have serious climate effects. A new type alternative proteins is now on menu, namely animal produced recombinantly by microbial fermentation. This technology, precision fermentation, projected to completely disrupt traditional animal-based agriculture. Certain milk egg along with specific meat substitute analog components fermentation already entering market. first wave products targets use these as protein additives, several commercial players active in field. The cost-efficiency requirements involve titers above 50 g/L which orders magnitude higher than those for pharmaceutical manufacture, making strain engineering, process optimization, scale-up critical success factors. development within defines a research direction integrating biotechnology, food production.
Язык: Английский
Процитировано
23
Clean Technologies and Environmental Policy, Год журнала: 2024, Номер unknown
Опубликована: Май 7, 2024
Язык: Английский
Процитировано
9
Renewable and Sustainable Energy Reviews, Год журнала: 2025, Номер 213, С. 115456 - 115456
Опубликована: Фев. 9, 2025
Язык: Английский
Процитировано
1
Grand challenges in biology and biotechnology, Год журнала: 2020, Номер unknown
Опубликована: Янв. 1, 2020
Язык: Английский
Процитировано
67
Bioresource Technology, Год журнала: 2021, Номер 345, С. 126531 - 126531
Опубликована: Дек. 9, 2021
Язык: Английский
Процитировано
48
Communications Biology, Год журнала: 2024, Номер 7(1)
Опубликована: Июль 24, 2024
Abstract A major roadblock towards the realisation of a circular economy are lack high-value products that can be generated from waste. Black soldier flies (BSF; Hermetia illucens ) gaining traction for their ability to rapidly consume large quantities organic wastes. However, these primarily used produce small variety products, such as animal feed ingredients and fertiliser. Using synthetic biology, BSF could developed into novel sustainable biomanufacturing platform valorise broader waste feedstocks enhanced feeds, biomolecules including industrial enzymes lipids, improved
Язык: Английский
Процитировано
8
Applied Microbiology and Biotechnology, Год журнала: 2024, Номер 108(1)
Опубликована: Янв. 10, 2024
Application of filamentous fungi for the production commercial enzymes such as amylase, cellulase, or xylanase is on rise due to increasing demand degrade several complex carbohydrates raw material biotechnological processes. Also, protein by food and feed gains importance. In any case, involves both cellular synthesis secretion outside cell. Unfortunately, proteins can be hampered accumulation unfolded misfolded in endoplasmic reticulum (ER) a result too high (heterologous) expression. To cope with this ER stress, cell generates response known (UPR). Even though mechanism should re-establish homeostasis equivalent under non-stress conditions, enzyme expression might still suffer from repression secretory stress (RESS). Among eukaryotes, Saccharomyces cerevisiae only fungus, which studied quite extensively unravel UPR pathway. Several homologs involved signal transduction cascade are also found fungi. Since RESS seems absent S. was reported Trichoderma reesei presence folding glycosylation inhibitors dithiothreitol tunicamycin, more in-depth study about mechanism, specifically fungi, need hour. Hence, review article gives an overview both, associated responses KEY POINTS: • Enzymes produced crucial industrial processes conserved among many but mediated different not fully understood industrially relevant
Язык: Английский
Процитировано
6