Journal of lasers in medical sciences,
Год журнала:
2019,
Номер
10(4), С. 317 - 323
Опубликована: Окт. 1, 2019
Introduction:
Transcranial
near-infrared
photobiomodulation
(NIR-PBM)
is
a
new
noninvasive
procedure
which
transcranially
applies
wavelength
to
the
scalp
with
laser
or
light-emitting
diode
(LED)
source.
Improvement
in
neurological
psychological
symptoms
has
been
reported
following
light
irradiation.
However,
our
knowledge,
there
no
study
investigate
effects
of
transcranial
NIR-PBM
on
motor
performance
directly.
Therefore,
objective
this
was
short-term
healthy
human
subjects.
Methods:
In
experimental
single-blind
randomized
clinical
trial
study,
56
right-handed
participants,
whose
ages
ranged
from
18
30,
were
randomly
assigned
(1)
Real
NIR-PBMC3
group
(n=14),
(2)
Sham
(3)
NIR-PBMC4
and
(4)
(n=14).
We
applied
808
nm
irradiation
energy
density
60
J/cm2
power
200
mw/cm2
C3
C4
points
scalp.
The
number
finger
taps
as
an
indicator
assessed
by
finger-tapping
test
(FTT)
before
after
corresponding
for
5
minutes.
Results:
results
showed
that
both
right
left
hands
use
real
significantly
increased
(P<0.05).
Conclusion:
concluded
using
source
point
cortex
people
can
increase
improvement.
Journal of Translational Medicine,
Год журнала:
2023,
Номер
21(1)
Опубликована: Фев. 22, 2023
Abstract
Cognitive
function
is
an
important
ability
of
the
brain,
but
cognitive
dysfunction
can
easily
develop
once
brain
injured
in
various
neuropathological
conditions
or
diseases.
Photobiomodulation
therapy
a
type
noninvasive
physical
that
gradually
emerging
field
neuroscience.
Transcranial
photobiomodulation
has
been
commonly
used
to
regulate
neural
activity
superficial
cortex.
To
stimulate
deeper
activity,
advanced
techniques
conjunction
with
photosensitive
nanoparticles
have
developed.
This
review
addresses
mechanisms
on
neurons
and
networks
discusses
advantages,
disadvantages
potential
applications
alone
combination
nanoparticles.
its
associated
strategies
may
provide
new
breakthrough
treatments
for
improvement.
Frontiers in Neuroscience,
Год журнала:
2022,
Номер
16
Опубликована: Июль 28, 2022
Over
the
last
seventy
years
or
so,
many
previous
studies
have
shown
that
photobiomodulation,
use
of
red
to
near
infrared
light
on
body
tissues,
can
improve
central
and
peripheral
neuronal
function
survival
in
both
health
disease.
These
improvements
are
thought
arise
principally
from
an
impact
photobiomodulation
mitochondrial
non-mitochondrial
mechanisms
a
range
different
cell
types,
including
neurones.
This
has
downstream
effects
stimulatory
protective
genes.
An
often-neglected
feature
nearly
all
these
is
they
been
induced
during
state
wakefulness.
Recent
when
applied
sleep,
also
be
benefit,
but
way,
by
improving
flow
cerebrospinal
fluid
clearance
toxic
waste-products
brain.
In
this
review,
we
consider
potential
differential
dependent
arousal.
We
speculate
cells
systems
depending
whether
it
wakefulness
may
follow
circadian
rhythm.
further
arousal-dependent
mediated
through
biophoton
–
ultra-weak
emission
network
communication
repair
across
Journal of NeuroEngineering and Rehabilitation,
Год журнала:
2024,
Номер
21(1)
Опубликована: Апрель 10, 2024
Abstract
A
systematic
review
was
conducted
to
determine
the
trends
in
devices
and
parameters
used
for
brain
photobiomodulation
(PBM).
The
revised
studies
included
clinical
cadaveric
approaches,
which
light
stimuli
were
applied
head
and/or
neck.
PubMed,
Scopus,
Web
of
Science
Google
Scholar
databases
search.
total
2133
records
screened,
from
97
this
review.
that
extracted
analysed
each
article
device
design,
actuation
area,
site,
wavelength,
mode
operation,
power
density,
energy
output,
per
session
treatment
time.
To
organize
information,
11
categories
defined,
according
their
characteristics.
most
category
laser
handpieces,
relate
21%
all
devices,
while
28%
not
described.
Studies
cognitive
function
physiological
characterisation
are
well
defined
ones
with
more
tangible
results.
There
is
a
lack
consistency
when
reporting
PBM
studies,
several
articles
under
defining
stimulation
protocol,
wide
variety
same
health
conditions
(e.g.,
Alzheimer’s
or
Parkinson’s
disease)
resulting
positive
outcomes.
Standardization
report
these
warranted,
as
sham-controlled
comparative
have
greatest
effect
on
treatments
different
neurological
conditions.
Reviews in the Neurosciences,
Год журнала:
2023,
Номер
34(6), С. 671 - 693
Опубликована: Март 17, 2023
Abstract
In
recent
years,
transcranial
photobiomodulation
(tPBM)
has
been
developing
as
a
promising
method
to
protect
and
repair
brain
tissues
against
damages.
The
aim
of
our
systematic
review
is
examine
the
results
available
in
literature
concerning
efficacy
tPBM
changing
activity
humans,
either
healthy
individuals,
or
patients
with
neurological
diseases.
Four
databases
were
screened
for
references
containing
terms
encompassing
photobiomodulation,
activity,
imaging,
human.
We
also
analysed
quality
included
studies
using
validated
tools.
Results
subjects
showed
that
even
after
single
session,
can
be
effective
influencing
activity.
particular,
different
approaches
–
focal
stimulation
helmet
global
seemed
act
at
both
vascular
level
by
increasing
regional
cerebral
blood
flow
(rCBF)
neural
neurons.
addition,
was
sufficient
induce
change
functional
connectivity
across
networks.
disease
sparser;
nevertheless,
they
indicated
could
improve
rCBF
several
regions.
Our
highlighted
heterogeneity
methods
generated,
together
need
more
randomised
controlled
trials
summary,
on
function,
but
consistency
needed
order
appreciate
fully
underlying
mechanisms
precise
outcomes.
Journal of Alzheimer s Disease,
Год журнала:
2021,
Номер
83(4), С. 1513 - 1519
Опубликована: Авг. 17, 2021
Photobiomodulation
(PBM)
affects
local
blood
flow
regulation
through
nitric
oxide
generation,
and
various
studies
have
reported
on
its
effect
improving
cognitive
function
in
neurodegenerative
diseases.
However,
the
of
PBM
areas
vertebral
arteries
(VA)
internal
carotid
(ICA),
which
are
major
blood-supplying
to
brain,
has
not
been
previously
investigated.We
aimed
determine
whether
irradiating
VA
ICA,
improved
regional
cerebral
(rCBF)
function.Fourteen
patients
with
mild
impairments
were
treated
PBM.
Cognitive
assessment
single-photon
emission
computed
tomography
implemented
at
baseline
end
PBM.Regarding
rCBF,
statistically
significant
trends
found
medial
prefrontal
cortex,
lateral
anterior
cingulate
occipital
cortex.
Based
assessments,
overall
function,
memory,
frontal/executive
function.We
confirmed
possibility
that
treatment
ICA
could
positively
affect
by
increasing
rCBF.
A
study
a
larger
sample
size
is
needed
validate
potential
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(13), С. 10946 - 10946
Опубликована: Июнь 30, 2023
The
global
number
of
people
with
Alzheimer’s
disease
(AD)
doubles
every
5
years.
It
has
been
established
that
unless
an
effective
treatment
for
AD
is
found,
the
incidence
will
triple
by
2060.
However,
pharmacological
therapies
have
failed
to
show
effectiveness
and
safety.
Therefore,
search
alternative
methods
treating
urgent
problem
in
medicine.
lymphatic
drainage
removal
system
brain
(LDRSB)
plays
important
role
resistance
progression
AD.
development
augmentation
LDRSB
functions
may
contribute
progress
therapy.
Photobiomodulation
(PBM)
considered
be
a
non-pharmacological
safe
approach
Here,
we
highlight
most
recent
relevant
studies
PBM
We
focus
on
emerging
evidence
indicates
potential
benefits
during
sleep
modulation
natural
activation
at
nighttime,
providing
metabolites,
including
amyloid-β,
from
brain,
leading
reduced
Our
review
creates
new
niche
therapy
diseases
sheds
light
smart
technologies
neurodegenerative
diseases.
Pharmaceuticals,
Год журнала:
2024,
Номер
17(6), С. 788 - 788
Опубликована: Июнь 16, 2024
The
COVID-19
pandemic,
caused
by
infection
with
the
SARS-CoV-2
virus,
is
associated
cognitive
impairment
and
Alzheimer’s
disease
(AD)
progression.
Once
it
enters
brain,
virus
stimulates
accumulation
of
amyloids
in
brain
that
are
highly
toxic
to
neural
cells.
These
may
trigger
neurological
symptoms
COVID-19.
meningeal
lymphatic
vessels
(MLVs)
play
an
important
role
removal
toxins
mediate
viral
drainage
from
brain.
MLVs
considered
a
promising
target
prevent
COVID-19-exacerbated
dementia.
However,
there
limited
methods
for
augmentation
MLV
function.
This
review
highlights
new
discoveries
field
COVID-19-mediated
amyloid
development
strategies
stimulate
clearance
through
other
pathways.
based
on
innovative
treating
dysfunction
induced
infection,
including
use
photobiomodulation,
plasmalogens,
medicinal
herbs,
which
offer
hope
addressing
challenges
posed
virus.
