Short-term Effects of Transcranial Near-Infrared Photobiomodulation on Motor Performance in Healthy Human Subjects: An Experimental SingleBlind Randomized Clinical Trial DOI Open Access

Atefeh Fekri,

Ali Jahan, Maryam Moghadam Salimi

et al.

Journal of lasers in medical sciences, Journal Year: 2019, Volume and Issue: 10(4), P. 317 - 323

Published: Oct. 1, 2019

Introduction: Transcranial near-infrared photobiomodulation (NIR-PBM) is a new noninvasive procedure which transcranially applies wavelength to the scalp with laser or light-emitting diode (LED) source. Improvement in neurological psychological symptoms has been reported following light irradiation. However, our knowledge, there no study investigate effects of transcranial NIR-PBM on motor performance directly. Therefore, objective this was short-term healthy human subjects. Methods: In experimental single-blind randomized clinical trial study, 56 right-handed participants, whose ages ranged from 18 30, were randomly assigned (1) Real NIR-PBMC3 group (n=14), (2) Sham (3) NIR-PBMC4 and (4) (n=14). We applied 808 nm irradiation energy density 60 J/cm2 power 200 mw/cm2 C3 C4 points scalp. The number finger taps as an indicator assessed by finger-tapping test (FTT) before after corresponding for 5 minutes. Results: results showed that both right left hands use real significantly increased (P<0.05). Conclusion: concluded using source point cortex people can increase improvement.

Language: Английский

Advances in photobiomodulation for cognitive improvement by near-infrared derived multiple strategies DOI Creative Commons

Wei‐tong Pan,

Pan‐Miao Liu,

Daqing Ma

et al.

Journal of Translational Medicine, Journal Year: 2023, Volume and Issue: 21(1)

Published: Feb. 22, 2023

Abstract Cognitive function is an important ability of the brain, but cognitive dysfunction can easily develop once brain injured in various neuropathological conditions or diseases. Photobiomodulation therapy a type noninvasive physical that gradually emerging field neuroscience. Transcranial photobiomodulation has been commonly used to regulate neural activity superficial cortex. To stimulate deeper activity, advanced techniques conjunction with photosensitive nanoparticles have developed. This review addresses mechanisms on neurons and networks discusses advantages, disadvantages potential applications alone combination nanoparticles. its associated strategies may provide new breakthrough treatments for improvement.

Language: Английский

Citations

37
The effect of photobiomodulation on the brain during wakefulness and sleep DOI Creative Commons

Cécile Moro,

Audrey Valverde, Marjorie Dole

et al.

Frontiers in Neuroscience, Journal Year: 2022, Volume and Issue: 16

Published: July 28, 2022

Over the last seventy years or so, many previous studies have shown that photobiomodulation, use of red to near infrared light on body tissues, can improve central and peripheral neuronal function survival in both health disease. These improvements are thought arise principally from an impact photobiomodulation mitochondrial non-mitochondrial mechanisms a range different cell types, including neurones. This has downstream effects stimulatory protective genes. An often-neglected feature nearly all these is they been induced during state wakefulness. Recent when applied sleep, also be benefit, but way, by improving flow cerebrospinal fluid clearance toxic waste-products brain. In this review, we consider potential differential dependent arousal. We speculate cells systems depending whether it wakefulness may follow circadian rhythm. further arousal-dependent mediated through biophoton – ultra-weak emission network communication repair across

Language: Английский

Citations

35
Devices used for photobiomodulation of the brain—a comprehensive and systematic review DOI Creative Commons
Filipa Fernandes, Sofia Oliveira, Francisca Monteiro

et al.

Journal of NeuroEngineering and Rehabilitation, Journal Year: 2024, Volume and Issue: 21(1)

Published: April 10, 2024

Abstract A systematic review was conducted to determine the trends in devices and parameters used for brain photobiomodulation (PBM). The revised studies included clinical cadaveric approaches, which light stimuli were applied head and/or neck. PubMed, Scopus, Web of Science Google Scholar databases search. total 2133 records screened, from 97 this review. that extracted analysed each article device design, actuation area, site, wavelength, mode operation, power density, energy output, per session treatment time. To organize information, 11 categories defined, according their characteristics. most category laser handpieces, relate 21% all devices, while 28% not described. Studies cognitive function physiological characterisation are well defined ones with more tangible results. There is a lack consistency when reporting PBM studies, several articles under defining stimulation protocol, wide variety same health conditions (e.g., Alzheimer’s or Parkinson’s disease) resulting positive outcomes. Standardization report these warranted, as sham-controlled comparative have greatest effect on treatments different neurological conditions.

Language: Английский

Citations

8
Can transcranial photobiomodulation improve cognitive function? A systematic review of human studies DOI
Tsz‐lok Lee, Zihan Ding, Agnes S. Chan

et al.

Ageing Research Reviews, Journal Year: 2022, Volume and Issue: 83, P. 101786 - 101786

Published: Nov. 9, 2022

Language: Английский

Citations

27
A systematic review of the effects of transcranial photobiomodulation on brain activity in humans DOI
Marjorie Dole, Vincent Auboiroux,

Lilia Langar

et al.

Reviews in the Neurosciences, Journal Year: 2023, Volume and Issue: 34(6), P. 671 - 693

Published: March 17, 2023

Abstract In recent years, transcranial photobiomodulation (tPBM) has been developing as a promising method to protect and repair brain tissues against damages. The aim of our systematic review is examine the results available in literature concerning efficacy tPBM changing activity humans, either healthy individuals, or patients with neurological diseases. Four databases were screened for references containing terms encompassing photobiomodulation, activity, imaging, human. We also analysed quality included studies using validated tools. Results subjects showed that even after single session, can be effective influencing activity. particular, different approaches – focal stimulation helmet global seemed act at both vascular level by increasing regional cerebral blood flow (rCBF) neural neurons. addition, was sufficient induce change functional connectivity across networks. disease sparser; nevertheless, they indicated could improve rCBF several regions. Our highlighted heterogeneity methods generated, together need more randomised controlled trials summary, on function, but consistency needed order appreciate fully underlying mechanisms precise outcomes.

Language: Английский

Citations

15
Transcranial Photobiomodulation Improves Cognitive Performance in Young Healthy Adults: A Systematic Review and Meta-Analysis DOI
Farzad Salehpour, Alireza Majdi,

Mahdiyeh Pazhuhi

et al.

Photobiomodulation Photomedicine and Laser Surgery, Journal Year: 2019, Volume and Issue: 37(10), P. 635 - 643

Published: Sept. 24, 2019

Transcranial photobiomodulation (t-PBM) is a noninvasive modality that may improve cognitive function in both healthy and diseased subjects.

Language: Английский

Citations

37
Photobiomodulation as a promising new tool in the management of psychological disorders: A systematic review DOI
Alba Gutiérrez‐Menéndez,

Marta Marcos-Nistal,

Marta Méndez

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2020, Volume and Issue: 119, P. 242 - 254

Published: Oct. 15, 2020

Language: Английский

Citations

35
Effects of Photobiomodulation on Changes in Cognitive Function and Regional Cerebral Blood Flow in Patients with Mild Cognitive Impairment: A Pilot Uncontrolled Trial DOI
Ji Soo Baik, Tae Young Lee, Nam Gyun Kim

et al.

Journal of Alzheimer s Disease, Journal Year: 2021, Volume and Issue: 83(4), P. 1513 - 1519

Published: Aug. 17, 2021

Photobiomodulation (PBM) affects local blood flow regulation through nitric oxide generation, and various studies have reported on its effect improving cognitive function in neurodegenerative diseases. However, the of PBM areas vertebral arteries (VA) internal carotid (ICA), which are major blood-supplying to brain, has not been previously investigated.We aimed determine whether irradiating VA ICA, improved regional cerebral (rCBF) function.Fourteen patients with mild impairments were treated PBM. Cognitive assessment single-photon emission computed tomography implemented at baseline end PBM.Regarding rCBF, statistically significant trends found medial prefrontal cortex, lateral anterior cingulate occipital cortex. Based assessments, overall function, memory, frontal/executive function.We confirmed possibility that treatment ICA could positively affect by increasing rCBF. A study a larger sample size is needed validate potential

Language: Английский

Citations

28
Phototherapy of Alzheimer’s Disease: Photostimulation of Brain Lymphatics during Sleep: A Systematic Review DOI Open Access
Oxana Semyachkina‐Glushkovskaya, Thomas Penzel, М Г Полуэктов

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(13), P. 10946 - 10946

Published: June 30, 2023

The global number of people with Alzheimer’s disease (AD) doubles every 5 years. It has been established that unless an effective treatment for AD is found, the incidence will triple by 2060. However, pharmacological therapies have failed to show effectiveness and safety. Therefore, search alternative methods treating urgent problem in medicine. lymphatic drainage removal system brain (LDRSB) plays important role resistance progression AD. development augmentation LDRSB functions may contribute progress therapy. Photobiomodulation (PBM) considered be a non-pharmacological safe approach Here, we highlight most recent relevant studies PBM We focus on emerging evidence indicates potential benefits during sleep modulation natural activation at nighttime, providing metabolites, including amyloid-β, from brain, leading reduced Our review creates new niche therapy diseases sheds light smart technologies neurodegenerative diseases.

Language: Английский

Citations

13
Promising Strategies to Reduce the SARS-CoV-2 Amyloid Deposition in the Brain and Prevent COVID-19-Exacerbated Dementia and Alzheimer’s Disease DOI Creative Commons
Nikita Navolokin,

Viktoria Adushkina,

Daria Zlatogorskaya

et al.

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(6), P. 788 - 788

Published: June 16, 2024

The COVID-19 pandemic, caused by infection with the SARS-CoV-2 virus, is associated cognitive impairment and Alzheimer’s disease (AD) progression. Once it enters brain, virus stimulates accumulation of amyloids in brain that are highly toxic to neural cells. These may trigger neurological symptoms COVID-19. meningeal lymphatic vessels (MLVs) play an important role removal toxins mediate viral drainage from brain. MLVs considered a promising target prevent COVID-19-exacerbated dementia. However, there limited methods for augmentation MLV function. This review highlights new discoveries field COVID-19-mediated amyloid development strategies stimulate clearance through other pathways. based on innovative treating dysfunction induced infection, including use photobiomodulation, plasmalogens, medicinal herbs, which offer hope addressing challenges posed virus.

Language: Английский

Citations

5