Antioxidants,
Год журнала:
2024,
Номер
13(9), С. 1129 - 1129
Опубликована: Сен. 18, 2024
spp.
are
often
used
as
food
and
in
traditional
medicine,
their
biological
activities
anti-inflammatory
diuretic,
for
wound
healing,
antimicrobial
agents
have
been
largely
reviewed.
The
aim
of
this
work
was
to
investigate
the
polyphenol
content
antioxidant
anti-tyrosinase
properties
extracts
from
Nutrients,
Год журнала:
2024,
Номер
16(15), С. 2550 - 2550
Опубликована: Авг. 3, 2024
Polyphenols
are
natural
compounds
which
plant-based
bioactive
molecules,
and
have
been
the
subject
of
growing
interest
in
recent
years.
Characterized
by
multiple
varieties,
polyphenols
mostly
found
fruits
vegetables.
Currently,
many
diseases
waiting
for
a
cure
or
solution
to
reduce
their
symptoms.
However,
drug
other
chemical
strategies
limitations
using
treatment
agent
still
detection
tool
diseases,
thus
researchers
need
investigate
preventive
improving
treatment.
Therefore,
it
is
elucidate
polyphenols,
bioactivity
effects,
supplementation,
consumption.
The
disadvantage
that
they
limited
bioavailability,
although
beneficial
outcomes
with
roles.
In
this
context,
several
different
developed
improve
particularly
liposomal
nanoparticles.
As
nutrition
one
most
important
factors
health,
inclusion
molecules
daily
diet
significant
continues
be
enthusiastically
researched.
Nutrition,
individuals
all
ages,
key
polyphenols.
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(14), С. 11751 - 11751
Опубликована: Июль 21, 2023
Grape
stems
have
emerged
as
a
promising
natural
ingredient
in
the
cosmetics
industry
due
to
their
abundance
of
phenolic
compounds,
known
for
antioxidant
and
anti-inflammatory
properties.
These
compounds
shown
great
potential
promoting
skin
health,
fighting
signs
aging,
shielding
against
environmental
stressors.
With
high
concentrations
resveratrol,
flavonoids,
tannins,
grape
garnered
attention
from
cosmetic
scientists.
Research
has
indicated
that
extracted
possess
potent
abilities,
effectively
combating
free
radicals
accelerate
aging.
Moreover,
these
demonstrated
capacity
shield
UV
damage,
boost
collagen
production,
enhance
elasticity.
Cosmetic
formulations
incorporating
stem
extracts
displayed
results
addressing
various
concerns,
including
reducing
wrinkles,
fine
lines,
age
spots,
leading
more
youthful
appearance.
Additionally,
exhibited
properties,
soothing
irritated
diminishing
redness.
Exploring
paves
way
sustainable
beauty
products.
By
harnessing
benefits
stems,
can
provide
effective
eco-friendly
solutions
consumers
seeking
alternatives.
Ongoing
research
holds
promise
innovative
stem-based
could
revolutionize
market,
fully
unlocking
extraordinary
botanical
treasures.
BMC Complementary Medicine and Therapies,
Год журнала:
2024,
Номер
24(1)
Опубликована: Апрель 8, 2024
Gels
loaded
with
nanocarriers
offer
interesting
ways
to
create
novel
therapeutic
approaches
by
fusing
the
benefits
of
gel
and
nanotechnology.
Clinical
studies
indicate
that
lavender
oil
(Lav-O)
has
a
positive
impact
on
accelerating
wound
healing
properly
based
its
antimicrobial
anti-inflammatory
effects.
Initially
Lav-O
Solid
Lipid
Nanoparticles
(Lav-SLN)
were
prepared
incorporating
cholesterol
lecithin
natural
lipids
SLNs
characterized.
Next,
3%
SLN
containing
topical
(Lav-SLN-G)
was
formulated
using
Carbopol
940.
Both
Lav-SLN
Lav-SLN-G
assessed
in
terms
antibacterial
effects
against
S.
aureus.
Lav-SLNs
revealed
particle
size
19.24
nm,
zeta
potential
-21.6
mv
EE%
75.46%.
Formulated
presented
an
acceptable
pH
texture
properties.
Minimum
Inhibitory/Bactericidal
Concentration
(MIC/MBC)
aureus
for
LAv-O,
0.12
0.24
mgml
Cosmetics,
Год журнала:
2024,
Номер
11(5), С. 157 - 157
Опубликована: Сен. 12, 2024
The
burgeoning
interest
in
natural
components
personal
care
products
has
led
to
significant
research
and
development
of
ingredients
such
as
plant
extracts,
antioxidants,
peptides,
probiotics.
These
have
been
recognized
for
their
potential
enhance
skin
health
through
various
mechanisms,
addressing
consumer
demand
that
are
both
effective
benign.
Plant
known
rich
composition
bioactive
compounds,
offer
a
myriad
benefits
including
antioxidant,
anti-inflammatory,
antimicrobial
properties,
making
them
invaluable
formulations.
Antioxidants,
derived
from
plants
other
sources,
play
pivotal
role
protecting
the
oxidative
damage,
thereby
preventing
premature
aging
promoting
vitality.
Bioactive
peptides
garnered
attention
owing
multifunctional
activities
include
collagen
synthesis,
inhibiting
enzymes
responsible
degradation,
reducing
inflammation,
contributing
regeneration
anti-aging.
Probiotics
expanded
utility
beyond
gut
care,
where
they
help
maintaining
microbiome
balance,
thus
enhancing
barrier
function
potentially
mitigating
disorders.
purpose
this
review
is
explore
individual
roles
probiotics
products,
while
emphasizing
synergistic
effects
when
combined.
By
integrating
these
components,
paper
aims
highlight
developing
innovative
skincare
formulations
not
only
address
specific
concerns
but
also
contribute
overall
health,
aligning
with
increasing
preference
holistic
solutions.
Heliyon,
Год журнала:
2025,
Номер
11(2), С. e41718 - e41718
Опубликована: Янв. 1, 2025
The
suppression
of
tyrosinase
(TYR),
a
key
enzyme
in
melanogenesis,
has
been
suggested
as
an
effective
strategy
for
preventing
melanin
accumulation.
We
previously
discovered
the
novel
chrysin
derivative
hydroxyethyl
(HE-chrysin)
through
irradiation
technique,
which
exerted
higher
anti-inflammatory
and
anti-cancer
activities
than
original
chrysin.
In
present
study,
we
explored
whether
HE-chrysin
antioxidant
anti-melanogenic
capacity
using
vitro
B16F10
murine
melanoma
cells
silico
molecular
docking.
exhibited
enhanced
DPPH,
ABTS,
FRAP
assays,
it
decreased
cellular
H2O2-stimulated
reactive
oxygen
species
levels
comparison
to
At
2.5
μM,
reduced
3-isobutyl-1-methylxanthine-stimulated
production
significantly
by
suppressing
intracellular
TYR
activity
without
cytotoxicity.
Furthermore,
docking
showed
that
inhibited
interacting
with
residues
(Glu256
Asn260)
chelating
Cu+
ions
at
active
site,
binding
free
energy
-7.00
kcal/mol
compared
arbutin
(-5.12
kcal/mol).
Our
findings
show
is
candidate
potential
use
dermatologic
therapy.
Macromolecular Bioscience,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 28, 2025
Abstract
Dermatological
diseases
represent
one
of
the
most
prevalent
health
concerns
globally,
with
associated
care
and
treatment
costs
having
consistently
increased
over
past
decade.
Current
therapeutic
modalities,
including
topical
medications,
oral
pharmaceuticals,
physical
therapies,
frequently
face
challenges
such
as
inadequate
drug
absorption
substantial
adverse
effects.
Microneedles,
recognized
minimally
invasive
delivery
systems,
effectively
penetrate
cutaneous
barrier
to
enhance
permeability
efficacy.
Polyphenols—abundant
in
botanical
marine
sources—demonstrate
diverse
pharmacological
properties
encompassing
anti‐inflammatory
antioxidant
activities.
The
integration
polyphenols
microneedle
technology
has
emerged
a
promising
strategy
for
dermatological
conditions,
demonstrating
significant
clinical
potential.
This
review
examines
multifunctional
capabilities
polyphenol‐incorporated
microneedles
elucidates
their
mechanisms
action
managing
disorders.
Furthermore,
it
synthesizes
recent
progress
polyphenol‐based
applications
various
pathologies,
acne
vulgaris,
psoriasis,
atopic
dermatitis.
Finally,
current
is
discussed
proposed
future
research
directions
optimizing
polyphenol
systems
therapeutics.
Journal of Research in Pharmacy,
Год журнала:
2025,
Номер
29(1), С. 396 - 406
Опубликована: Март 3, 2025
This
study
examined
the
anti-aging
effect
of
Chinese
perfume
(Aglaia
odorata)
and
Indian
camphorweed
(Pluchea
indica)
leaf
extracts
on
Saccharomyces
cerevisiae
as
a
model
system.
Investigation
antioxidant
activity
bioactive
compounds
using
GC–MS
qualitative
spot
tests
were
performed
to
determine
effects.
In
addition,
quantitative
test
was
conducted
high-throughput
chronological
lifespan
analysis.
The
results
showed
that
enzyme
activities
SOD,
APX,
CAT
in
leaves
393.96
units/min/g
FW,
215
µmoles
H2O2/min/g
5.6
H2O2
decomposed/min/g
respectively;
values
717.57
48
12.33
µmole
respectively.
577.2
µg/mL
348.86
µg/mL.
extract
included
n-hexadecanoic
acid,
β
turmerone,
2-propenoic
3-phenyl-,
methyl
ester
(methyl
cinnamate)
those
from
acid
neophytadiene.
Treatment
with
both
prolonged
life
yeast
after
15
days
incubation.
stress
conditions,
yeasts
better
growth
addition
extracts.
revealed
demonstrate
promising
potential
ingredients
for
cosmetics.