The Effect of Maturity Stage on Polyphenolic Composition, Antioxidant and Anti-Tyrosinase Activities of Ficus rubiginosa Desf. ex Vent. Extracts DOI Creative Commons

Ghaid W. A. Abualzulof,

Samir Scandar, Ina Varfaj

и другие.

Antioxidants, Год журнала: 2024, Номер 13(9), С. 1129 - 1129

Опубликована: Сен. 18, 2024

spp. are often used as food and in traditional medicine, their biological activities anti-inflammatory diuretic, for wound healing, antimicrobial agents have been largely reviewed. The aim of this work was to investigate the polyphenol content antioxidant anti-tyrosinase properties extracts from

Язык: Английский

Cancer treatment therapies: traditional to modern approaches to combat cancers DOI
Rasanpreet Kaur, Alok Bhardwaj, Saurabh Gupta

и другие.

Molecular Biology Reports, Год журнала: 2023, Номер 50(11), С. 9663 - 9676

Опубликована: Окт. 12, 2023

Язык: Английский

Процитировано

123

Polyphenols: Secondary Metabolites with a Biological Impression DOI Open Access
Ecem Bolat, Sümeyye Sarıtaş, Hatice Duman

и другие.

Nutrients, Год журнала: 2024, Номер 16(15), С. 2550 - 2550

Опубликована: Авг. 3, 2024

Polyphenols are natural compounds which plant-based bioactive molecules, and have been the subject of growing interest in recent years. Characterized by multiple varieties, polyphenols mostly found fruits vegetables. Currently, many diseases waiting for a cure or solution to reduce their symptoms. However, drug other chemical strategies limitations using treatment agent still detection tool diseases, thus researchers need investigate preventive improving treatment. Therefore, it is elucidate polyphenols, bioactivity effects, supplementation, consumption. The disadvantage that they limited bioavailability, although beneficial outcomes with roles. In this context, several different developed improve particularly liposomal nanoparticles. As nutrition one most important factors health, inclusion molecules daily diet significant continues be enthusiastically researched. Nutrition, individuals all ages, key polyphenols.

Язык: Английский

Процитировано

19

Revealing the Beauty Potential of Grape Stems: Harnessing Phenolic Compounds for Cosmetics DOI Open Access
Monica C. Serra, Ana Casas, J. A. Teixeira

и другие.

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(14), С. 11751 - 11751

Опубликована: Июль 21, 2023

Grape stems have emerged as a promising natural ingredient in the cosmetics industry due to their abundance of phenolic compounds, known for antioxidant and anti-inflammatory properties. These compounds shown great potential promoting skin health, fighting signs aging, shielding against environmental stressors. With high concentrations resveratrol, flavonoids, tannins, grape garnered attention from cosmetic scientists. Research has indicated that extracted possess potent abilities, effectively combating free radicals accelerate aging. Moreover, these demonstrated capacity shield UV damage, boost collagen production, enhance elasticity. Cosmetic formulations incorporating stem extracts displayed results addressing various concerns, including reducing wrinkles, fine lines, age spots, leading more youthful appearance. Additionally, exhibited properties, soothing irritated diminishing redness. Exploring paves way sustainable beauty products. By harnessing benefits stems, can provide effective eco-friendly solutions consumers seeking alternatives. Ongoing research holds promise innovative stem-based could revolutionize market, fully unlocking extraordinary botanical treasures.

Язык: Английский

Процитировано

21

Development and characterization of a topical gel, containing lavender (Lavandula angustifolia) oil loaded solid lipid nanoparticles DOI Creative Commons

Faeze Fahimnia,

Mehran Nemattalab, Zahra Hesari

и другие.

BMC Complementary Medicine and Therapies, Год журнала: 2024, Номер 24(1)

Опубликована: Апрель 8, 2024

Gels loaded with nanocarriers offer interesting ways to create novel therapeutic approaches by fusing the benefits of gel and nanotechnology. Clinical studies indicate that lavender oil (Lav-O) has a positive impact on accelerating wound healing properly based its antimicrobial anti-inflammatory effects. Initially Lav-O Solid Lipid Nanoparticles (Lav-SLN) were prepared incorporating cholesterol lecithin natural lipids SLNs characterized. Next, 3% SLN containing topical (Lav-SLN-G) was formulated using Carbopol 940. Both Lav-SLN Lav-SLN-G assessed in terms antibacterial effects against S. aureus. Lav-SLNs revealed particle size 19.24 nm, zeta potential -21.6 mv EE% 75.46%. Formulated presented an acceptable pH texture properties. Minimum Inhibitory/Bactericidal Concentration (MIC/MBC) aureus for LAv-O, 0.12 0.24 mgml

Язык: Английский

Процитировано

6

Revolutionizing Cosmetic Ingredients: Harnessing the Power of Antioxidants, Probiotics, Plant Extracts, and Peptides in Personal and Skin Care Products DOI Creative Commons

Hye Yung Choi,

Yun Jung Lee, Chul Min Kim

и другие.

Cosmetics, Год журнала: 2024, Номер 11(5), С. 157 - 157

Опубликована: Сен. 12, 2024

The burgeoning interest in natural components personal care products has led to significant research and development of ingredients such as plant extracts, antioxidants, peptides, probiotics. These have been recognized for their potential enhance skin health through various mechanisms, addressing consumer demand that are both effective benign. Plant known rich composition bioactive compounds, offer a myriad benefits including antioxidant, anti-inflammatory, antimicrobial properties, making them invaluable formulations. Antioxidants, derived from plants other sources, play pivotal role protecting the oxidative damage, thereby preventing premature aging promoting vitality. Bioactive peptides garnered attention owing multifunctional activities include collagen synthesis, inhibiting enzymes responsible degradation, reducing inflammation, contributing regeneration anti-aging. Probiotics expanded utility beyond gut care, where they help maintaining microbiome balance, thus enhancing barrier function potentially mitigating disorders. purpose this review is explore individual roles probiotics products, while emphasizing synergistic effects when combined. By integrating these components, paper aims highlight developing innovative skincare formulations not only address specific concerns but also contribute overall health, aligning with increasing preference holistic solutions.

Язык: Английский

Процитировано

6

Anti-melanogenic effects of hydroxyethyl chrysin through the inhibition of tyrosinase activity: in vitro and in silico approaches DOI Creative Commons
Yuna Lee, Ha-Yeon Song,

Eui‐Baek Byun

и другие.

Heliyon, Год журнала: 2025, Номер 11(2), С. e41718 - e41718

Опубликована: Янв. 1, 2025

The suppression of tyrosinase (TYR), a key enzyme in melanogenesis, has been suggested as an effective strategy for preventing melanin accumulation. We previously discovered the novel chrysin derivative hydroxyethyl (HE-chrysin) through irradiation technique, which exerted higher anti-inflammatory and anti-cancer activities than original chrysin. In present study, we explored whether HE-chrysin antioxidant anti-melanogenic capacity using vitro B16F10 murine melanoma cells silico molecular docking. exhibited enhanced DPPH, ABTS, FRAP assays, it decreased cellular H2O2-stimulated reactive oxygen species levels comparison to At 2.5 μM, reduced 3-isobutyl-1-methylxanthine-stimulated production significantly by suppressing intracellular TYR activity without cytotoxicity. Furthermore, docking showed that inhibited interacting with residues (Glu256 Asn260) chelating Cu+ ions at active site, binding free energy -7.00 kcal/mol compared arbutin (-5.12 kcal/mol). Our findings show is candidate potential use dermatologic therapy.

Язык: Английский

Процитировано

0

Enhancement of wound healing by a bilayer hydrogel and nanofiber scaffold infused with Calophyllum inophyllum oil and Platostoma palustre aqueous extract DOI Creative Commons
Anh Hue Luong, Wei‐Chih Lin

Biomaterials Advances, Год журнала: 2025, Номер 172, С. 214247 - 214247

Опубликована: Фев. 27, 2025

Язык: Английский

Процитировано

0

Polyphenol Microneedles for Dermatological Therapy DOI
Chunlei Liu,

Jinhui Ran,

Xie Zhi-ping

и другие.

Macromolecular Bioscience, Год журнала: 2025, Номер unknown

Опубликована: Фев. 28, 2025

Abstract Dermatological diseases represent one of the most prevalent health concerns globally, with associated care and treatment costs having consistently increased over past decade. Current therapeutic modalities, including topical medications, oral pharmaceuticals, physical therapies, frequently face challenges such as inadequate drug absorption substantial adverse effects. Microneedles, recognized minimally invasive delivery systems, effectively penetrate cutaneous barrier to enhance permeability efficacy. Polyphenols—abundant in botanical marine sources—demonstrate diverse pharmacological properties encompassing anti‐inflammatory antioxidant activities. The integration polyphenols microneedle technology has emerged a promising strategy for dermatological conditions, demonstrating significant clinical potential. This review examines multifunctional capabilities polyphenol‐incorporated microneedles elucidates their mechanisms action managing disorders. Furthermore, it synthesizes recent progress polyphenol‐based applications various pathologies, acne vulgaris, psoriasis, atopic dermatitis. Finally, current is discussed proposed future research directions optimizing polyphenol systems therapeutics.

Язык: Английский

Процитировано

0

Analysis of anti-aging activity of Chinese perfume (Aglaia odorata) and Indian camphorweed (Pluchea indica) leaves using Saccharomyces cerevisiae model system DOI Open Access
Woro Anindito Sri Tunjung,

Lovy Perdani,

Nudia Mufidah Azasi

и другие.

Journal of Research in Pharmacy, Год журнала: 2025, Номер 29(1), С. 396 - 406

Опубликована: Март 3, 2025

This study examined the anti-aging effect of Chinese perfume (Aglaia odorata) and Indian camphorweed (Pluchea indica) leaf extracts on Saccharomyces cerevisiae as a model system. Investigation antioxidant activity bioactive compounds using GC–MS qualitative spot tests were performed to determine effects. In addition, quantitative test was conducted high-throughput chronological lifespan analysis. The results showed that enzyme activities SOD, APX, CAT in leaves 393.96 units/min/g FW, 215 µmoles H2O2/min/g 5.6 H2O2 decomposed/min/g respectively; values 717.57 48 12.33 µmole respectively. 577.2 µg/mL 348.86 µg/mL. extract included n-hexadecanoic acid, β turmerone, 2-propenoic 3-phenyl-, methyl ester (methyl cinnamate) those from acid neophytadiene. Treatment with both prolonged life yeast after 15 days incubation. stress conditions, yeasts better growth addition extracts. revealed demonstrate promising potential ingredients for cosmetics.

Язык: Английский

Процитировано

0

Current knowledge on selected stilbenes and their promising applications DOI

Marta Sharafan,

Magdalena Anna Malinowska, M. Drew Ferrier

и другие.

Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 225 - 288

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0