Signaling pathways governing glioma cancer stem cells behavior

Cellular Signalling, Год журнала: 2022, Номер 101, С. 110493 - 110493

Опубликована: Окт. 11, 2022

Язык: Английский

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Functional roles of lncRNA-TUG1 in hepatocellular carcinoma

Life Sciences, Год журнала: 2022, Номер 308, С. 120974 - 120974

Опубликована: Сен. 17, 2022

Язык: Английский

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Long Non-Coding RNAs in Colorectal Cancer: Navigating the Intersections of Immunity, Intercellular Communication, and Therapeutic Potential

Biomedicines, Год журнала: 2023, Номер 11(9), С. 2411 - 2411

Опубликована: Авг. 28, 2023

This comprehensive review elucidates the intricate roles of long non-coding RNAs (lncRNAs) within colorectal cancer (CRC) microenvironment, intersecting domains immunity, intercellular communication, and therapeutic potential. lncRNAs, which are significantly involved in pathogenesis CRC, immune evasion, treatment response to have crucial implications inflammation serve as promising candidates for novel strategies biomarkers. scrutinizes interaction lncRNAs with Consensus Molecular Subtypes (CMSs) their complex interplay tumor stroma affecting immunity inflammation, conveyance via extracellular vesicles, particularly exosomes. Furthermore, we delve into relationship between other RNAs, including microRNAs circular mediating cell-to-cell communication CRC microenvironment. Lastly, propose potential manipulate enhance anti-tumor thereby underlining significance devising innovative interventions CRC.

Язык: Английский

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LncRNA MALAT1-related signaling pathways in osteosarcoma

Clinical & Translational Oncology, Год журнала: 2022, Номер 25(1), С. 21 - 32

Опубликована: Июль 6, 2022

Язык: Английский

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Crosstalk between long non-coding RNAs and p53 signaling pathway in colorectal cancer: A review study

Pathology - Research and Practice, Год журнала: 2023, Номер 249, С. 154756 - 154756

Опубликована: Авг. 10, 2023

Язык: Английский

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Potential roles of lncRNA-XIST/miRNAs/mRNAs in human cancer cells

Clinical & Translational Oncology, Год журнала: 2023, Номер 25(7), С. 2015 - 2042

Опубликована: Фев. 28, 2023

Язык: Английский

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Regulation of immune-mediated chemoresistance in cancer by lncRNAs: an in-depth review of signaling pathways

Naunyn-Schmiedeberg s Archives of Pharmacology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 9, 2025

Язык: Английский

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The pathogenic roles of lncRNA-Taurine upregulated 1 (TUG1) in colorectal cancer

Cancer Cell International, Год журнала: 2022, Номер 22(1)

Опубликована: Ноя. 4, 2022

Abstract Colorectal cancer (CRC) is a gastrointestinal tumor that develops from the colon, rectum, or appendix. The prognosis of CRC patients especially those with metastatic lesions remains unsatisfactory. Although various conventional methods have been used for treatment CRC, early detection and identification molecular mechanisms associated necessary. scientific literature reports altered expression long non-coding RNAs (lncRNAs) contributed to pathogenesis cells. LncRNA TUG1 was reported target miRNAs signaling pathways mediate cell proliferation, migration, metastasis. Therefore, might be potent predictive/prognostic biomarker diagnosis CRC.

Язык: Английский

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Astragaloside IV inhibits epithelial-mesenchymal transition and pulmonary fibrosis via lncRNA-ATB/miR-200c/ZEB1 signaling pathway

Gene, Год журнала: 2023, Номер 897, С. 148040 - 148040

Опубликована: Дек. 6, 2023

Язык: Английский

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LncRNA THUMPD3-AS1 promotes invasion and EMT in gastric cancer by regulating the miR-1297/BCAT1 pathway

iScience, Год журнала: 2023, Номер 26(9), С. 107673 - 107673

Опубликована: Авг. 18, 2023

Long noncoding RNA (lncRNA) plays crucial roles in the development of gastric cancer (GC); however, studies their mechanisms action are needed to determine clinical value. The aim this study is explore effects and THUMPD3-AS1 GC. Elevated levels were observed GC demonstrated a significant positive correlation with poor prognosis. Functionally, promoted cell proliferation, migration, invasion, epithelial-mesenchymal transition (EMT) induced tumor growth vivo. exerts its regulatory function on BCAT1 through competitive binding miR-1297. Further investigations confirmed that both miR-1297 interact BCAT1. These findings suggest promotes invasion EMT by regulating miR-1297/BCAT1 pathway, indicating may serve as biomarker therapeutic target for

Язык: Английский

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