Frontiers in Bioengineering and Biotechnology,
Год журнала:
2024,
Номер
11
Опубликована: Янв. 11, 2024
Increasing
bacterial
resistance
and
the
negative
impact
of
currently
used
antibacterial
agents
have
produced
need
for
novel
anticancer
drugs.
In
this
regard,
nanotechnology
could
provide
safer
more
efficient
therapeutic
agents.
The
main
methods
nanoparticle
production
are
chemical
physical
approaches
that
often
costly
environmentally
unsafe.
current
study,
Pluchea
indica
leaf
extract
was
biosynthesis
bimetallic
selenium–gold
nanoparticles
(Se-Au
BNPs)
first
time.
Phytochemical
examinations
revealed
P.
includes
90.25
mg/g
dry
weight
(DW)
phenolics,
275.53
DW
flavonoids,
26.45
tannins.
X-ray
diffraction
(XRD),
transmission
electron
microscopy
(TEM),
Fourier-transform
infrared
(FTIR)
spectroscopy,
dynamic
light
scattering
(DLS),
scanning
(SEM),
energy-dispersive
spectroscopy
(EDX)
techniques
were
employed
to
characterize
Se-Au
BNPs.
Based
on
UV-vis
spectra,
absorbance
BNPs
peaked
at
238
374
nm.
SEM
imaging,
emerged
as
bright
particles,
both
Au
Se
uniformly
distributed
throughout
extract.
XRD
analysis
average
size
45.97
showed
properties
against
Escherichia
coli
,
Pseudomonas
aeruginosa
Staphylococcus
aureus
Bacillus
subtilis
with
minimum
inhibitory
concentrations
(MICs)
31.25,
15.62,
3.9
μg/mL,
respectively.
Surprisingly,
a
cytotoxicity
assay
IC
50
value
toward
Wi
38
normal
cell
line
116.8
implying
all
MICs
described
above
be
safely.
More
importantly,
shown
higher
efficacy
human
breast
cancer
cells
(MCF7),
an
13.77
μg/mL.
conclusion,
paper
is
data
effective
utilization
in
biologically
active
Polymers,
Год журнала:
2022,
Номер
14(16), С. 3352 - 3352
Опубликована: Авг. 17, 2022
Traditional
cancer
treatments
include
surgery,
radiation,
and
chemotherapy.
According
to
medical
sources,
chemotherapy
is
still
the
primary
method
for
curing
or
treating
today
has
been
a
major
contributor
recent
decline
in
mortality.
Nanocomposites
based
on
polymers
metal
nanoparticles
have
recently
received
attention
of
researchers.
In
current
study,
nanocomposite
was
fabricated
carboxymethyl
cellulose
silver
(CMC-AgNPs)
their
antibacterial,
antifungal,
anticancer
activities
were
evaluated.
The
antibacterial
results
revealed
that
CMC-AgNPs
promising
activity
against
Gram-negative
(Klebsiella
oxytoca
Escherichia
coli)
Gram-positive
bacteria
(Bacillus
cereus
Staphylococcus
aureus).
Moreover,
exhibited
antifungal
filamentous
fungi
such
as
Aspergillus
fumigatus,
A.
niger,
terreus.
Concerning
HepG2
hepatocellular
cell
line,
lowest
IC50
values
(7.9
±
0.41
µg/mL)
recorded
CMC-AgNPs,
suggesting
strong
cytotoxic
effect
liver
cells.
As
result,
our
findings
suggest
antitumor
these
CMC-Ag
due
induction
apoptosis
necrosis
hepatic
cells
via
increased
caspase-8
-9
diminished
levels
VEGFR-2.
conclusion,
activities,
which
can
be
used
pharmaceutical
fields.
Applied Biochemistry and Biotechnology,
Год журнала:
2023,
Номер
196(1), С. 85 - 98
Опубликована: Апрель 26, 2023
Abstract
New
and
creative
methodologies
for
the
fabrication
of
silver
nanoparticles
(Ag-NPs),
which
are
exploited
in
a
wide
range
consumer
items,
significant
interest.
Hence,
this
research
emphasizes
biological
approach
Ag-NPs
through
Egyptian
henna
leaves
(
Lawsonia
inermis
Linn.)
extracts
analysis
prepared
Ag-NPs.
Plant
extract
components
were
identified
by
gas
chromatography
mass
spectrometry
(GC-mass).
The
analyses
carried
out
UV–visible
(UV–Vis),
X-ray
diffraction
(XRD),
transmission
electron
microscope
(TEM),
scanning
(SEM),
Fourier
transform
infrared
(FTIR)
analysis.
UV–Vis
reveals
that
have
maximum
peak
at
460
nm
visible
light.
Structural
characterization
recorded
peaks
corresponded
to
Bragg’s
diffractions
nano-crystal,
with
average
crystallite
sizes
varying
from
28
60
nm.
Antibacterial
activities
examined,
it
is
observed
all
microorganisms
very
sensitive
biologically
synthesized
Journal of Functional Biomaterials,
Год журнала:
2022,
Номер
13(3), С. 112 - 112
Опубликована: Авг. 2, 2022
In
the
current
study,
prickly
pear
peel
waste
(PPPW)
extract
was
used
for
biosynthesis
of
selenium
nanoparticles
through
a
green
and
eco-friendly
method
first
time.
The
biosynthesized
SeNPs
were
characterized
using
UV-Vis,
XRD,
FTIR,
TEM,
SEM,
EDX,
mapping.
Characterization
results
revealed
that
spherical,
polydisperse,
highly
crystalline,
had
sizes
in
range
10-87.4
nm.
Antibacterial,
antifungal,
insecticidal
activities
evaluated.
Results
exhibited
promising
antibacterial
against
Gram
negative
(E.
coli
P.
aeruginosa)
positive
(B.
subtilis
S.
aureus)
bacteria
where
MICs
125,
62.5,
15.62
µg/mL,
respectively.
Moreover,
showed
potential
antifungal
activity
toward
Candida
albicans
Cryptococcus
neoformans
3.9
7.81
Furthermore,
tested
crud
severely
induced
larvicidal
mosquitoes
with
LC50
LC90
219.841,
950.087
mg/L
75.411,
208.289
mg/L,
fecundity
hatchability
C.
pipiens
mosquito
significantly
decreased
as
applied
concentrations
increased
either
crude
or
fabricated
extracts.
conclusion,
have
antibacterial,
activities,
which
can
be
biomedical
environmental
applications.
Biomass Conversion and Biorefinery,
Год журнала:
2023,
Номер
14(17), С. 20345 - 20357
Опубликована: Апрель 6, 2023
Abstract
In
the
last
two
decades,
nanomaterials
have
received
much
attention
for
treatment
of
multidrug-resistant
microbes
that
threaten
human
health.
current
study,
novelty
and
scientific
significance
concentrated
on
biogenic
synthesis
bimetallic
silver-zinc
oxide
nanoparticles
(Ag-ZnO
NPs)
using
pomegranate
peel
extract
(PPE)
first
time.
The
new
constructed
Ag-ZnO
NPs
possessed
synergistic
activity
at
a
low
concentration
to
avoid
toxicity
elevate
superior
potential.
UV-Vis.
characterization
illustrated
were
small
in
size
(15.8
nm),
which
was
observed
395.0
nm.
SEM
image
NPs,
incorporated
with
PPE,
exhibited
uniform
NP
surfaces
clear
surface
appearance.
It
can
be
detected
isolated
typically
as
rounded
particle
across
showed
brilliant
combined
stabilized
prepared
PPE.
Results
also
revealed
potential
antibacterial
toward
Escherichia
coli
,
Pseudomonas
aeruginosa
Bacillus
subtilis
Staphylococcus
aureus
Enterococcus
faecalis
where
minimum
inhibitory
concentrations
(MICs)
62.5,
125,
15.62,
250
µg/ml.
Likewise,
appeared
antifungal
against
Candida
albicans
Cryptococcus
neoformans
Aspergillus
fumigatus
brasiliensis
MICs
7.81,
31.25,
62.5
µg/ml,
respectively.
Moreover,
anticancer
activities
MCF7
Caco2,
IC
50
104.9
52.4
Additionally,
these
are
safe
use
results
cytotoxicity
Vero
normal
cell
line
confirmed
155.1
Overall,
time,
successfully
biosynthesized
PPE;
also,
they
had
promising
antibacterial,
antifungal,
activities.
Molecules,
Год журнала:
2023,
Номер
28(15), С. 5812 - 5812
Опубликована: Авг. 1, 2023
In
the
current
study,
clove
oil
nanoemulsion
(CL-nanoemulsion)
and
emulsion
(CL-emulsion)
were
prepared
through
an
ecofriendly
method.
The
CL-nanoemulsion
CL-emulsion
characterized
using
dynamic
light
scattering
(DLS)
a
transmission
electron
microscope
(TEM),
where
results
illustrated
that
droplets
approximately
32.67
nm
in
size
spherical
shape,
while
225.8
with
shape.
antibacterial
activity
of
was
carried
out
microbroth
dilution
Results
revealed
preferred
had
minimal
MIC
values
between
0.31
5
mg/mL.
antibiofilm
efficacy
against
S.
aureus
significantly
decreased
development
biofilm
compared
CL-emulsion.
Furthermore,
showed
antifungal
higher
than
Moreover,
exhibited
outstanding
efficiency
toward
Candida
albicans,
Cryptococcus
neoformans,
Aspergillus
brasiliensis,
A.
flavus,
fumigatus
MICs
12.5,
3.12,
0.78,
1.56,
1.56
mg/mL,
respectively.
Additionally,
analyzed
for
its
antineoplastic
effects
modified
MTT
assay
evaluating
apoptotic
cytotoxic
HepG2
MCF-7
cell
lines.
breast
cancer
cells
lowest
IC50
(3.4-fold)
relative
to
Thus,
induces
apoptosis
by
inducing
caspase-8
-9
suppressing
VEGFR-2.
conclusion,
antibacterial,
antifungal,
as
well
anticancer
properties,
which
can
be
used
different
biomedical
applications
after
extensive
studies
vivo.
Reactions,
Год журнала:
2024,
Номер
5(1), С. 135 - 194
Опубликована: Фев. 1, 2024
Contemporary
technological
and
industrial
advancements
have
led
to
increased
reliance
on
chemicals
for
product
innovation,
leading
heightened
contamination
of
water
sources
by
traditional
pollutants
(organic
dyes,
heavy
metals)
disease-causing
microorganisms.
Wastewater
treatment
processes
now
reveal
“emerging
pollutants”,
including
pharmaceuticals,
endocrine
disruptors,
agricultural
chemicals.
While
some
are
benign,
certain
emerging
can
harm
diverse
organisms.
Researchers
seek
cost-effective
purification
methods
that
completely
degrade
without
generating
harmful
by-products.
Semiconductor-based
photocatalytic
degradation,
particularly
using
titanium
dioxide
(TiO2),
is
popular
addressing
pollution.
This
study
focuses
recent
applications
TiO2
nanostructures
in
photocatalysis
eliminating
various
pollutants.
Structural
modifications,
like
doping
nanocomposite
formation,
enhance
photocatalyst
performance.
The
emphasizes
elimination
mechanisms
comprehensively
discusses
factors
impacting
both
the
mechanism
performance
nano-TiO2-based
photocatalysts.
Characteristics
TiO2,
such
as
crystal
structure
energy
band-gap,
along
with
its
activity
mechanism,
presented.
review
covers
advantages
limitations
different
nanostructure
production
approaches
addresses
potential
toxicity
human
health
environment.
In
summary,
this
provides
a
holistic
perspective
applying
nano-TiO2
materials
mitigate
