Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 197 - 217
Опубликована: Янв. 1, 2024
Язык: Английский
Advanced Drug Delivery Reviews, Год журнала: 2023, Номер 197, С. 114821 - 114821
Опубликована: Апрель 9, 2023
Язык: Английский
Процитировано
94
Journal of Controlled Release, Год журнала: 2024, Номер 366, С. 519 - 534
Опубликована: Янв. 11, 2024
Язык: Английский
Процитировано
45
Exploration, Год журнала: 2024, Номер 4(6)
Опубликована: Март 24, 2024
Abstract Photothermal therapy (PTT) has garnered significant attention in recent years, but the standalone application of PTT still faces limitations that hinder its ability to achieve optimal therapeutic outcomes. Nitric oxide (NO), being one most extensively studied gaseous molecules, presents itself as a promising complementary candidate for PTT. In response, various nanosystems have been developed enable simultaneous utilization and NO‐mediated gas (GT), with integration photothermal agents (PTAs) thermally‐sensitive NO donors prevailing approach. This combination seeks leverage synergistic effects GT while mitigating potential risks associated toxicity through use single laser irradiation. Furthermore, additional internal or external stimuli employed trigger release when combined different types PTAs, thereby further enhancing efficacy. comprehensive review aims summarize advancements gas‐assisted cancer treatment. It commences by providing an overview precursors, including those sensitive photothermal, light, ultrasound, reactive oxygen species, glutathione. These precursors are discussed context dual‐modal PTT/GT. Subsequently, incorporation other treatment modalities such chemotherapy (CHT), photodynamic (PDT), alkyl radical therapy, radiation immunotherapy (IT) creation triple‐modal nanoplatforms is presented. The explores tetra‐modal therapies, PTT/GT/CHT/PDT, PTT/GT/CHT/chemodynamic (CDT), PTT/GT/PDT/IT, PTT/GT/starvation (ST)/IT, PTT/GT/Ca 2+ overload/IT, PTT/GT/ferroptosis (FT)/IT, PTT/GT/CDT/IT. Finally, challenges future perspectives concerning these novel paradigms discussed. anticipated serve valuable resource studies focused on development innovative photothermal/NO‐based nanotheranostics.
Язык: Английский
Процитировано
42
Advanced Healthcare Materials, Год журнала: 2024, Номер 14(4)
Опубликована: Ноя. 6, 2024
Cancer remains one of the most challenging health issues globally, demanding innovative therapeutic approaches for effective treatment. Nanoparticles, particularly those composed gold, silver, and iron oxide, have emerged as promising candidates changing cancer therapy. This comprehensive review demonstrates landscape nanoparticle-based oncological interventions, focusing on remarkable advancements potentials oxide nanoparticles. Gold nanoparticles garnered significant attention their exceptional biocompatibility, tunable surface chemistry, distinctive optical properties, rendering them ideal various diagnostic strategies. Silver nanoparticles, renowned antimicrobial exhibit potential in therapy through multiple mechanisms, including apoptosis induction, angiogenesis inhibition, drug delivery enhancement. With magnetic properties offer unique diagnosis targeted opportunities. critically examines recent synthesis, functionalization, biomedical applications these Moreover, challenges are discussed, toxicity concerns, immunogenicity, translational barriers, ongoing efforts to overcome hurdles highlighted. Finally, insights into future directions regulatory considerations, provided aiming accelerate translation technologies from bench bedside.
Язык: Английский
Процитировано
15
Advanced Drug Delivery Reviews, Год журнала: 2024, Номер 206, С. 115188 - 115188
Опубликована: Янв. 23, 2024
Язык: Английский
Процитировано
10
Journal of Radioanalytical and Nuclear Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Янв. 6, 2025
Язык: Английский
Процитировано
2
Nanoscale, Год журнала: 2023, Номер 15(44), С. 17658 - 17697
Опубликована: Янв. 1, 2023
Camptothecin (CPT) is a cytotoxic alkaloid that attenuates the replication of cancer cells via blocking DNA topoisomerase 1.
Язык: Английский
Процитировано
20
Meme sağlığı dergisi/Meme sağlığı dergisi, Год журнала: 2025, Номер 21(1), С. 9 - 15
Опубликована: Янв. 2, 2025
Key Points •Topical therapies are localized treatments that target the breast tumour location specifically.• By limiting drug's exposure to rest of body, this strategy lowers possibility systemic adverse effects. •The efficacy therapy may be increased by direct application location.• These function directly targeting cancer cells through skin penetration, which can help minimise size and relieve symptoms.• To increase overall effectiveness treatment, topical frequently used in conjunction with other including radiation, surgery, or chemotherapy.
Язык: Английский
Процитировано
1
Journal of Materials Chemistry B, Год журнала: 2024, Номер unknown
Опубликована: Янв. 1, 2024
Photothermal therapy (PTT), a recently emerging method for eradicating tumors, utilizes hyperthermia induced by photo-absorbing materials to generate heat within cancer cells. Gold nanoparticles (AuNPs) have gained reliability
Язык: Английский
Процитировано
5
Drug Discovery Today, Год журнала: 2024, Номер 29(9), С. 104101 - 104101
Опубликована: Июль 16, 2024
Язык: Английский
Процитировано
4