Revista Digital Universitaria,
Год журнала:
2023,
Номер
24(5)
Опубликована: Сен. 13, 2023
En
las
últimas
décadas,
el
consumo
de
fructosa
en
México
se
ha
incrementado
dramáticamente.
Este
azúcar
utiliza
como
endulzante
refrescos,
jugos
embotellados,
cereales,
panadería,
lácteos
y
caramelos.
Su
diario
está
asociado
con
desarrollo
síndrome
metabólico,
diabetes,
obesidad
efectos
dañinos
cerebro,
que
alteran
apetito,
ciclo
sueño-vigilia,
la
neurogénesis,
aprendizaje
memoria.
El
objetivo
este
artículo
es
describir
gran
variedad
nocivos
para
salud
generados
por
excesivo
fructosa.
Frontiers in Physiology,
Год журнала:
2023,
Номер
14
Опубликована: Июль 3, 2023
Chronic
intake
of
high
amounts
fructose
has
been
linked
to
the
development
metabolic
disorders,
which
attributed
almost
complete
clearance
by
liver.
However,
direct
measurement
hepatic
uptake
is
complicated
fact
that
portal
vein
difficult
access.
Here
we
present
a
new,
non-invasive
method
measure
and
metabolism
with
use
deuterium
imaging
(DMI)
upon
administration
[6,6’-
2
H
]fructose.
Using
both
]glucose
]fructose,
determined
differences
in
glucose
mouse
liver
dynamic
DMI.
The
deuterated
compounds
were
administered
either
fast
intravenous
(IV)
bolus
injection
or
slow
IV
infusion.
Directly
after
more
than
two-fold
higher
initial
subsequent
2.5-fold
faster
decay
was
observed
as
compared
]glucose.
In
contrast,
infusion
fructose,
fructose/glucose
signal
maximum
spectra
lower
glucose.
With
protocols,
labeling
water
These
observations
are
line
extraction
turnover
liver,
DMI
]fructose
could
potentially
contribute
better
understanding
healthy
human
aberrations
diseases.
Terapevticheskii arkhiv,
Год журнала:
2024,
Номер
96(5), С. 447 - 452
Опубликована: Июнь 3, 2024
This
article
examines
the
role
of
uric
acid
(UA)
in
cognitive
changes
and
neurodegeneration,
focusing
on
its
functions
as
an
antioxidant
prooxidant.
Research
suggests
that
serum
UA
levels
may
be
associated
with
development
or
delay
impairment,
especially
context
neurodegenerative
diseases
such
Alzheimer's
disease.
It
was
revealed
there
is
a
relationship
between
level
dynamics
functions,
indicating
potential
neuroprotective
properties
UA.
Particular
attention
paid
to
balance
prooxidant
UA,
which
play
key
protecting
neurons
from
damage.
However,
research
results
are
not
clear-cut,
highlighting
need
for
further
more
fully
understand
processes.
Determining
optimal
important
step
developing
strategies
prevention
treatment
impairment
neurodegeneration.
Overall,
these
studies
advance
understanding
mechanisms
underlying
interaction
metabolism
brain
health.
Current Medical Research and Opinion,
Год журнала:
2024,
Номер
unknown, С. 1 - 15
Опубликована: Окт. 28, 2024
Objective
This
study
aims
to
evaluate
the
diagnostic
significance
of
serum
uric
acid
(UA),
glutathione
(GSH),
and
amyloid-β1-42
(Aβ1-42)
levels
in
relation
disease
progression
cognitive
impairment
patients
with
Parkinson's
(PD).
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(21), С. 11689 - 11689
Опубликована: Окт. 30, 2024
Diabetes
is
a
major
risk
factor
for
Alzheimer's
disease
(AD).
Amino
acid
compound
2
(AAC2)
improves
glycemic
and
cognitive
functions
in
diabetic
mouse
models
through
mechanisms
distinct
from
insulin.
Our
goal
was
to
compare
the
effects
of
AAC2,
insulin,
their
nanofiber-forming
combination
on
early
asymptomatic
AD
pathogenesis
APP/PS1
mice.
Insulin,
but
not
AAC2
or
treatment
(administered
intraperitoneally
every
48
h
120
days),
increased
seizure-related
mortality,
altered
brain
fat-to-lean
mass
ratio,
improved
specific
NanoString
pathway
analysis
cerebral
gene
expression
revealed
dysregulated
synaptic
mechanisms,
with
upregulation
Revista Digital Universitaria,
Год журнала:
2023,
Номер
24(5)
Опубликована: Сен. 13, 2023
En
las
últimas
décadas,
el
consumo
de
fructosa
en
México
se
ha
incrementado
dramáticamente.
Este
azúcar
utiliza
como
endulzante
refrescos,
jugos
embotellados,
cereales,
panadería,
lácteos
y
caramelos.
Su
diario
está
asociado
con
desarrollo
síndrome
metabólico,
diabetes,
obesidad
efectos
dañinos
cerebro,
que
alteran
apetito,
ciclo
sueño-vigilia,
la
neurogénesis,
aprendizaje
memoria.
El
objetivo
este
artículo
es
describir
gran
variedad
nocivos
para
salud
generados
por
excesivo
fructosa.
