Reviews in Cardiovascular Medicine, Год журнала: 2023, Номер 24(8), С. 238 - 238
Опубликована: Авг. 18, 2023
Relative-tachycardia (RT), a phenomenon of unproportionately high heart-rate elevation in response to fever, has been previously attributed unfavourable outcomes severe-inflammatory-response-syndrome (SIRS). Relative body-temperature ratio (RHR) and its prognostic associations patients with severe critical coronavirus disease 2019 (COVID-19) have not investigated.
Язык: Английский
Nature Reviews Neurology, Год журнала: 2024, Номер 20(2), С. 99 - 113
Опубликована: Янв. 11, 2024
Язык: Английский
Процитировано
20
Healthcare, Год журнала: 2023, Номер 11(8), С. 1095 - 1095
Опубликована: Апрель 11, 2023
Coronavirus disease 2019 (COVID-19) sequelae (or long COVID) has become a clinically significant concern. Several studies have reported the relationship between heart rate variability (HRV) parameters and COVID-19. This review investigates long-term association COVID-19 HRV parameters. Four electronic databases were searched up to 29 July 2022. We included observational comparing (measurement durations: 1 min or more) in participants with without history of used assessment tools developed by National Heart, Lung, Blood Institute group evaluate methodological quality studies. Eleven cross-sectional compared individuals who recovered from acute infection controls (n = 2197). Most standard deviation normal-to-normal intervals (SDNN) root mean square successive differences. The was not optimal. generally found decreased SDNN parasympathetic activity post-COVID-19 individuals. Compared controls, decreases observed had COVID. emphasized inhibition conditions. Due limitations measuring parameters, findings should be further validated robust prospective longitudinal
Язык: Английский
Процитировано
27
Frontiers in Cardiovascular Medicine, Год журнала: 2023, Номер 10
Опубликована: Сен. 1, 2023
Long COVID is characterized by persistent signs and symptoms that continue or develop for more than 4 weeks after acute COVID-19 infection. Patients with experience a cardiovascular autonomic imbalance known as dysautonomia. However, the underlying pathophysiological mechanisms behind this remain unclear. Current hypotheses include neurotropism, cytokine storms, inflammatory persistence. Certain immunological factors indicate autoimmune dysfunction, which can be used to identify patients at higher risk of COVID. Heart rate variability imbalances in individuals suffering from COVID, measurement non-invasive low-cost method assessing modulation. Additionally, biochemical markers are diagnosing monitoring These improve understanding driving response its effects on sympathetic parasympathetic pathways nervous system. Autonomic may result lower heart variability, impaired vagal activity, substantial sympathovagal imbalance. New research subject must encouraged enhance long-term risks cause
Язык: Английский
Процитировано
27
Mechanisms of Ageing and Development, Год журнала: 2024, Номер 218, С. 111915 - 111915
Опубликована: Фев. 13, 2024
Язык: Английский
Процитировано
5
International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(4), С. 2296 - 2296
Опубликована: Фев. 15, 2024
Autoimmune autonomic ganglionopathy (AAG) is a disease of failure caused by ganglionic acetylcholine receptor (gAChR) autoantibodies. Although the detection autoantibodies important for distinguishing from other neuropathies that present with dysfunction, factors are accurate diagnosis. Here, we provide comprehensive review clinical features AAG, highlighting differences in course, presentation, and laboratory findings presenting symptoms. The first step diagnosing AAG careful history taking, which should reveal whether mode onset acute or chronic, followed an examination time course progression, including presentation extra-autonomic neuropathy be differentiated when patient presents dysfunction. Immune-mediated neuropathies, such as sensory neuropathy, sometimes difficult to differentiate, therefore, well understood. Other non-neuropathic conditions, postural orthostatic tachycardia syndrome, chronic fatigue long COVID, also symptoms similar those AAG. often challenging, efforts made differentiate among candidates.
Язык: Английский
Процитировано
4
Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 437 - 457
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
PeerJ, Год журнала: 2025, Номер 13, С. e19089 - e19089
Опубликована: Март 10, 2025
Background Coronavirus disease 2019 (COVID-19) is a multisystem infectious which affected 5.7 million people in Portugal. A subgroup of patients experienced long-term effects from the infection, now referred to as long COVID. Long COVID can considerably reduce quality life (QoL) patients. This study aimed evaluate impact on QoL and work performance among healthcare workers (HCWs) Methods cross-sectional correlational survey was performed 348 HCWs employed either hospitals, or non-hospital health facilities Participants completed an online using Google Forms between May June 2024, consisted multiple-choice questions took less than 10 min fill out. considered present if defined symptoms started at least 3 months after primary infection COVID-19, persisted for 2 months. The outcome measures were QoL. Performance measured seven-point Likert scale evaluated Satisfaction with Life Scale (SWLS). Data analyzed SPSS. Results total 277 participants (79.6%) had history SARS-CoV-2 223 (64.1%) reported Extreme fatigue by 158 (57.0%), cognitive dysfunction 118 (42.6%), shortness breath 76 (27.4%), persistent cough 168 (60.6%). In multivariate analysis, significantly associated lower SWLS scores indicating that negatively impacted Having two more chronic diseases showed trend towards performance, extreme strong negative associations performance. Discussion Based national sample (348 individuals), high percentage These results suggest Portugal have prevalence similar worldwide population. Concerning work, having well dysfunction. Interestingly, we found association being clinical secretary SWLS. might be explained specific challenges stressors faced secretaries, could their conclusion, prevalent studied strongly suggests need targeted care group. this guide authorities addressing important consequences should rehabilitation programs post-COVID-19 recovery.
Язык: Английский
Процитировано
0
BioScience Trends, Год журнала: 2023, Номер 17(2), С. 85 - 116
Опубликована: Март 13, 2023
Over three years have passed since the COVID-19 pandemic started. The dangerousness and impact of should definitely not be ignored or underestimated. Other than symptoms acute infection, long-term associated with SARS-CoV-2 which are referred to here as "sequelae long COVID (LC)", also a conspicuous global public health concern. Although such sequelae were well-documented, understanding insights regarding LC-related remain inadequate due limitations previous studies (the follow-up, methodological flaws, heterogeneity among studies, etc.). Notably, robust evidence diagnosis treatment certain LC insufficient has been stumbling block better management these patients. This awkward situation motivated us conduct this review. Here, we comprehensively reviewed updated information, particularly focusing on clinical issues. We attempt provide latest information by systematically reviewing involvement main organ systems. propose paths for future exploration based available knowledge authors' experience. believe that take-home messages will helpful gain into ultimately benefit practice in treating sequelae.
Язык: Английский
Процитировано
9
Annals of Allergy Asthma & Immunology, Год журнала: 2024, Номер 133(5), С. 522 - 530
Опубликована: Авг. 23, 2024
Язык: Английский
Процитировано
3
The Medical Journal of Australia, Год журнала: 2024, Номер 221(S9)
Опубликована: Ноя. 3, 2024
Immune dysregulation is a key aspect of post-acute sequelae coronavirus disease 2019 (PASC), also known as long COVID, with sustained activation immune cells, T cell exhaustion, skewed B profiles, and disrupted communication thereby resulting in autoimmune-related complications. The gut emerging critical link between microbiota, metabolism overall dysfunction, potentially sharing similarities other chronic fatigue conditions PASC. Immunothrombosis neurological signalling dysfunction emphasise the complex interplay system, blood clotting, central nervous system context severe acute respiratory syndrome 2 (SARS-CoV-2) infection. Clear research gaps design PASC studies, especially longitudinal research, stand out significant areas concern.
Язык: Английский
Процитировано
3