Mapping evolution and trends of cell membrane-coated nanoparticles: A bibliometric analysis and scoping review DOI Creative Commons
Chong Li, Jing Hu,

Jing He

и другие.

Nanotechnology Reviews, Год журнала: 2024, Номер 13(1)

Опубликована: Янв. 1, 2024

Abstract The limitations of traditional drug therapy have driven the creation and development novel cell membrane-coated nanoparticle (CMNP) platforms. Since introduction CMNP concept method in 2011, an increasing number studies focusing on this field been widely conducted. Despite growing body literature, comprehensive bibliometric analysis is still lacking. This study conducted a CMNP-related publications sourced from Web Science Core Collection database, covering period January 1, to December 31, 2023. included co-authorships, co-citations, co-occurrences countries, institutions, authors, references, keywords. Visualized tools such as Citespace, VOSviewer, R Package Bibliometrix were employed present data. A total 780 included, with China contributing highest (75.64%, n = 590). annual increased consistently 2011 2023, indicating global interest field. Prof. Liangfang Zhang United States recognized founder leading figure area. top three academic journals field, based publication volume, are ACS Nano (32 publications, IF 2022 17.1), Applied Materials Interfaces 9.5), Advanced Functional (31 19) among 185 scholarly journals. Reference keyword revealed that erythrocytes macrophage membranes significant research hotspots. primary diseases targeted by cancer pulmonary inflammation. In addition, CMNPs frequently studied conjunction photothermal photodynamic therapy. Furthermore, also summarized timelines for various membrane coating methods three-step preparation process CMNP. provides valuable insights guide future highlighting importance clinical application. Research nanomaterials, particularly those related inflammation, expected remain focal point. there need further other potential nanomaterials. serves resource researchers quickly comprehensively understand current hotspots emerging frontiers

Язык: Английский

Smart Hydrogels for Bone Reconstruction via Modulating the Microenvironment DOI Creative Commons

Weikai Chen,

Hao Zhang,

Qirong Zhou

и другие.

Research, Год журнала: 2023, Номер 6

Опубликована: Янв. 1, 2023

Rapid and effective repair of injured or diseased bone defects remains a major challenge due to shortages implants. Smart hydrogels that respond internal external stimuli achieve therapeutic actions in spatially temporally controlled manner have recently attracted much attention for therapy regeneration. These can be modified by introducing responsive moieties embedding nanoparticles increase their capacity repair. Under specific stimuli, smart variable, programmable, controllable changes on demand modulate the microenvironment promoting healing. In this review, we highlight advantages summarize materials, gelation methods, properties. Then, overview recent advances developing biochemical signals, electromagnetic energy, physical including single, dual, multiple types enable physiological pathological modulating microenvironment. discuss current challenges future perspectives regarding clinical translation hydrogels.

Язык: Английский

Процитировано

58
Physical strategies to engineer supramolecular composite hydrogels for advanced biomedical applications DOI

Sravan Baddi,

Auphedeous Y. Dang-i,

Fengli Gao

и другие.

Progress in Materials Science, Год журнала: 2025, Номер 151, С. 101428 - 101428

Опубликована: Янв. 9, 2025

Язык: Английский

Процитировано

2
Bone‐Targeted Biomimetic Nanogels Re‐Establish Osteoblast/Osteoclast Balance to Treat Postmenopausal Osteoporosis DOI
Yongzhi Cui,

Bin Lv,

Zhongying Li

и другие.

Small, Год журнала: 2023, Номер 20(6)

Опубликована: Окт. 4, 2023

Abstract Insufficient bone formation and excessive resorption caused by estrogen deficiency are the major factors resulting in incidence of postmenopausal osteoporosis (PMOP). The existing drugs usually fail to re‐establish osteoblast/osteoclast balance from both sides generate side‐effects owing lack bone‐targeting ability. Here, engineered cell‐membrane‐coated nanogels PNG@mR&C capable scavenging receptor activator nuclear factor‐κB ligand (RANKL) responsively releasing therapeutic PTH 1–34 microenvironment prepared RANK CXCR4 overexpressed mesenchymal stem cell (BMSC) membrane‐coated chitosan biopolymers. on coated‐membranes confer ability, abundant effectively absorb RANKL inhibit osteoclastogenesis. Meanwhile, release triggered osteoclast‐mediated acid promote osteogenesis. In addition, dose frequency greatly reduced due smart property, prolonged circulation time, bone‐specific accumulation. Thus, exhibits satisfactory effects ovariectomized (OVX) mouse model. This study provides a new paradigm re‐establishing metabolic homeostasis multitargets shows great promise for treatment PMOP.

Язык: Английский

Процитировано

33
Biomimetic cell membrane-coated nanocarriers for targeted siRNA delivery in cancer therapy DOI
Xin Huang, Haoyu Guo, Lutong Wang

и другие.

Drug Discovery Today, Год журнала: 2023, Номер 28(4), С. 103514 - 103514

Опубликована: Фев. 2, 2023

Язык: Английский

Процитировано

27
Targeting ferroptosis unveils a new era for traditional Chinese medicine: a scientific metrology study DOI Creative Commons
Siyang Cao, Yihao Wei, Yaohang Yue

и другие.

Frontiers in Pharmacology, Год журнала: 2024, Номер 15

Опубликована: Фев. 14, 2024

In the past 11 years, there has been a surge in studies exploring regulatory effect of Traditional Chinese Medicine (TCM) on ferroptosis. However, significant gap persists comprehensive scientometric analysis and scientific mapping research, especially tracking evolution, primary contributors, emerging research focal points. This study aims to comprehensively update advancements targeting ferroptosis with various TCMs during previous years. The data, covering period from 1 January 2012, 30 November 2023, were retrieved Web Science database. For in-depth visualized analyses, series advanced analytical instruments employed. findings highlight China’s predominant role, accounting for 71.99% total publications significantly shaping this domain. Noteworthy productivity was observed at institutions, including Guangzhou University Medicine, Chengdu Zhejiang University. Thomas Efferth emerged as foremost author within field, while Frontiers Pharmacology boasted highest publication count. pinpointed hepatocellular carcinoma, chemical drug-induced liver injury, mitochondrial diseases, acute kidney failure most critical disorders addressed realm. offers bibliometric evaluation, enhancing our understanding present status TCM therapy managing ferroptosis-related diseases. Consequently, it aids both seasoned researchers newcomers by accelerating access vital information fostering innovative concept extraction specialized field.

Язык: Английский

Процитировано

10
Bone-brain interaction: mechanisms and potential intervention strategies of biomaterials DOI Creative Commons
Jinfang Yu,

Luli Ji,

Yongxian Liu

и другие.

Bone Research, Год журнала: 2025, Номер 13(1)

Опубликована: Март 17, 2025

Abstract Following the discovery of bone as an endocrine organ with systemic influence, bone-brain interaction has emerged a research hotspot, unveiling complex bidirectional communication between and brain. Studies indicate that brain can influence each other’s homeostasis via multiple pathways, yet there is dearth systematic reviews in this area. This review comprehensively examines interactions across three key areas: bone-derived factors on function, effects brain-related diseases or injuries (BRDI) health, concept skeletal interoception. Additionally, discusses innovative approaches biomaterial design inspired by mechanisms, aiming to facilitate through materiobiological aid treatment neurodegenerative bone-related diseases. Notably, integration artificial intelligence (AI) highlighted, showcasing AI’s role expediting formulation effective targeted strategies. In conclusion, offers vital insights into mechanisms suggests advanced harness these clinical practice. These offer promising avenues for preventing treating impacting skeleton brain, underscoring potential interdisciplinary enhancing human health.

Язык: Английский

Процитировано

1
Crosstalk between ferroptosis and chondrocytes in osteoarthritis: a systematic review of in vivo and in vitro studies DOI Creative Commons
Siyang Cao, Yihao Wei,

Huihui Xu

и другие.

Frontiers in Immunology, Год журнала: 2023, Номер 14

Опубликована: Июль 14, 2023

Purpose Recent scientific reports have revealed a close association between ferroptosis and the occurrence development of osteoarthritis (OA). Nevertheless, precise mechanisms by which influences OA how to hobble progression inhibiting chondrocyte not yet been fully elucidated. This study aims conduct comprehensive systematic review (SR) address these gaps. Methods Following guidelines Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) 2020, we conducted search Embase, Ovid, ProQuest, PubMed, Scopus, Cochrane Library, Web Science databases identify relevant studies that investigate chondrocytes in OA. Our included published from inception until January 31st, 2023. Only met predetermined quality criteria were this SR. Results In SR, total 21 specified considered suitable current updated synthesis. The underlying its with involve various biological phenomena, including mitochondrial dysfunction, dysregulated iron metabolism, oxidative stress, crucial signaling pathways. Conclusion Ferroptosis has opened an entirely new chapter investigation OA, targeted regulation it is springing up as attractive promising therapeutic tactic registration https://inplasy.com/inplasy-2023-3-0044/ , identifier INPLASY202330044.

Язык: Английский

Процитировано

15
A bibliometric and visualized analysis of nanoparticles in musculoskeletal diseases (from 2013 to 2023) DOI
Siyang Cao, Yihao Wei, Zhi Yao

и другие.

Computers in Biology and Medicine, Год журнала: 2023, Номер 169, С. 107867 - 107867

Опубликована: Дек. 20, 2023

Язык: Английский

Процитировано

14
Cell membrane coated nanoparticles: cutting-edge drug delivery systems for osteoporosis therapy DOI Creative Commons

Jiewen Liao,

Li Lü, Xiangyu Chu

и другие.

Nanoscale, Год журнала: 2024, Номер 16(17), С. 8236 - 8255

Опубликована: Янв. 1, 2024

The review delves into exploring diverse cellular sources for coating nanoparticles to treat osteoporosis. Furthermore, it highlights the pivotal role of these in restoring immune microenvironment, offering promising avenues combating

Язык: Английский

Процитировано

4
Mapping the evolution and research landscape of ferroptosis-targeted nanomedicine: insights from a scientometric analysis DOI Creative Commons
Siyang Cao, Yihao Wei, Yaohang Yue

и другие.

Frontiers in Pharmacology, Год журнала: 2024, Номер 15

Опубликована: Сен. 25, 2024

Notable progress has been made in "ferroptosis-based nano drug delivery systems (NDDSs)" over the past 11 years. Despite ongoing absence of a comprehensive scientometric overview and up-to-date scientific mapping research, especially regarding evolution, critical research pathways, current landscape, central investigative themes, future directions.

Язык: Английский

Процитировано

4