Multi‐Functional Bio‐HJzyme Engineered Polyetheretherketone Implant with Cascade‐Amplification Therapeutic Capabilities Toward Intractable Implant‐Associated Infections DOI Open Access
Jing Gong,

Shuangquan Lai,

Shuting Zhang

и другие.

Small, Год журнала: 2024, Номер unknown

Опубликована: Дек. 31, 2024

Intractable implant-associated infections (IAIs) are the primary cause of prosthetic implant failure, particularly in context diabetes mellitus. There is an urgent need to design and construct versatile engineered implants integrated with cascade amplification therapeutic modality significantly improve treatment diabetic IAIs. To address this issue, a multi-functional MXene/Ag

Язык: Английский

Biophysical-driven piezoelectric and aligned nanofibrous scaffold promotes bone regeneration by re-establishing physiological electrical microenvironment DOI

Aoao Wang,

Xinbo Ma, Yafeng Yang

и другие.

Nano Research, Год журнала: 2024, Номер 17(8), С. 7376 - 7393

Опубликована: Май 7, 2024

Язык: Английский

Процитировано

12
Stimuli‐Responsive NO Delivery Platforms for Bacterial Infection Treatment DOI
Yanling Hu, Meng Ding, Xinyi Lv

и другие.

Advanced Healthcare Materials, Год журнала: 2024, Номер 13(31)

Опубликована: Авг. 22, 2024

The prevalence of drug-resistant bacterial infections has emerged as a grave threat to clinical treatment and global human health, presenting one the foremost challenges in medical care. Thus, there is an urgent imperative develop safe efficacious novel antimicrobial strategies. Nitric oxide (NO) recognized endogenous signaling molecule, which plays pivotal role numerous pathological processes. Currently, NO garnered significant interest antibacterial agent due its capability eradicate bacteria, disrupt biofilms, facilitate wound healing, all while circumventing emergence drug resistance. However, inherently unstable characteristic therapeutic gas renders controlled administration gases exceedingly challenging. Hence, this review, current challenge infection discussed; then it briefly elucidated mechanism comprehensively delineate recent advancements stimulus-responsive delivery platforms, along with their merits, obstacles, prospective avenues for application. This review offers guidance future NO-medicated anti-infection therapy hoped.

Язык: Английский

Процитировано

8
An emodin-mediated multifunctional nanoplatform with augmented sonodynamic and immunoregulation for osteomyelitis therapy DOI
Zehao Li, Ying Lu, Jianbo Song

и другие.

Journal of Colloid and Interface Science, Год журнала: 2025, Номер 684, С. 122 - 137

Опубликована: Янв. 13, 2025

Язык: Английский

Процитировано

1
Recent advances in sonodynamic-derived synergistic strategies against bacterial infections DOI

Mengmeng Cheng,

Ling Zhou, Lili Zhang

и другие.

Chemical Engineering Journal, Год журнала: 2025, Номер 508, С. 160962 - 160962

Опубликована: Фев. 25, 2025

Язык: Английский

Процитировано

1
Dual-functional acridine-based coatings with anti-bacterial adhesion and durable photocatalytic antibacterial DOI

Linfeng Kang,

Houqian Peng,

Mingyuan Yang

и другие.

Progress in Organic Coatings, Год журнала: 2024, Номер 194, С. 108593 - 108593

Опубликована: Июнь 8, 2024

Язык: Английский

Процитировано

6
Sono-promoted piezocatalysis and low-dose drug penetration for personalized therapy via tumor organoids DOI

Zhiyi Gong,

Yiqian Mao,

Yichao Liu

и другие.

Journal of Colloid and Interface Science, Год журнала: 2024, Номер 675, С. 192 - 206

Опубликована: Июль 3, 2024

Язык: Английский

Процитировано

5
Surface modification strategies to reinforce the soft tissue seal at transmucosal region of dental implants DOI Creative Commons
Siqi Jin,

Yameng Yu,

Ting Zhang

и другие.

Bioactive Materials, Год журнала: 2024, Номер 42, С. 404 - 432

Опубликована: Сен. 10, 2024

Язык: Английский

Процитировано

5
Interface/Dipole Polarized Antibiotics‐Loaded Fe3O4/PB Nanoparticles for Non‐Invasive Therapy of Osteomyelitis Under Medical Microwave Irradiation DOI
Liguo Jin,

Hanpeng Liu,

Chaofeng Wang

и другие.

Advanced Materials, Год журнала: 2024, Номер unknown

Опубликована: Сен. 30, 2024

Abstract Due to their poor light penetration, photothermal therapy and photodynamic are ineffective in treating deep tissue infections, such as osteomyelitis caused by Staphylococcus aureus ( S. ). Here, a microwave (MW)‐responsive magnetic targeting composite system consisting of ferric oxide (Fe 3 O 4 )/Prussian blue (PB) nanoparticles, gentamicin (Gent), biodegradable poly(lactic‐co‐glycolic acid) (PLGA) is reported. The PLGA/Fe /PB/Gent complex used combination with MW thermal (MTT), dynamic (MDT), chemotherapy (CT) treat acute infected ‐infected. powerful antibacterial effect the determined synergistic effects heat reactive oxygen species (ROS) generation Fe /PB nanoparticles under irradiation effective release Gent at infection site via targeting. mechanism analyzed using bacterial transcriptome RNA sequencing. ROS reduce activity protein transporters on membrane, along transport various ions acceleration phosphate metabolism, which can lead increased permeability damage ribosome DNA, accompany internal efflux bacteria, thus effectively killing bacteria.

Язык: Английский

Процитировано

5
Piezotronic effect enhanced catalytic sterilization: mechanisms and practical applications DOI
Xiaoyu Zhang, Zhongwei Yang, Jian Zhang

и другие.

Nano Energy, Год журнала: 2024, Номер 131, С. 110346 - 110346

Опубликована: Окт. 10, 2024

Язык: Английский

Процитировано

4
Exogenous Electron Generation Techniques for Biomedical Applications: Bridging Fundamentals and Clinical Practice DOI
Yufei Tang, Shuqi Feng, Keyi Yao

и другие.

Biomaterials, Год журнала: 2025, Номер 317, С. 123083 - 123083

Опубликована: Янв. 5, 2025

Язык: Английский

Процитировано

0