Bioconjugate Chemistry,
Год журнала:
2024,
Номер
35(7), С. 1015 - 1023
Опубликована: Июнь 21, 2024
Currently,
clinical
therapeutic
strategies
for
nasopharyngeal
carcinoma
(NPC)
confront
insurmountable
dilemmas
in
which
surgical
resection
is
incomplete
and
chemotherapy/radiotherapy
has
significant
side
effects.
Phototherapy
offers
a
maneuverable,
effective,
noninvasive
pattern
NPC
therapy.
Herein,
we
developed
lysosome-targeted
pH-responsive
nanophototheranostic
near-infrared
II
(NIR-II)
fluorescence
imaging-guided
photodynamic
therapy
(PDT)
photothermal
(PTT)
of
NPC.
A
S-D-A-D-S-type
NIR-II
phototheranostic
molecule
(IRFEM)
encapsulated
within
the
acid-sensitive
amphiphilic
DSPE-Hyd-PEG2k
to
form
IRFEM@DHP
nanoparticles
(NPs).
The
prepared
exhibits
good
accumulation
acidic
lysosomes
facilitating
release
IRFEM,
could
disrupt
lysosomal
function
by
generating
an
amount
heat
ROS
under
laser
irradiation.
Moreover,
guidelines
enhance
accuracy
PTT/PDT
avoid
damage
normal
tissues.
Remarkably,
enable
efficient
antitumor
effects
both
Coordination Chemistry Reviews,
Год журнала:
2023,
Номер
500, С. 215499 - 215499
Опубликована: Ноя. 1, 2023
The
recent
advances
in
nanomaterials
have
led
to
speculation
about
the
effectivity
of
carbon
quantum
dots
applied
as
electrocatalysts
for
water
splitting.
An
insufficient
amount
research
has
been
undergone
into
this
proposed
application,
although
CQDs
exhibit
great
potential
with
rapid
electron
transfer
rates,
long-term
stability
and
desirable
morphologies.
To
evaluate
various
materials
that
could
aid
their
application
splitting,
investigate
environmentally
conscious
synthesis
routes
determine
whether
be
considered
commercial
applications,
numerous
studies
articles
were
collated
obtain
a
comprehensive
strategy
processing
analysing
data.
Further,
investigating
not
only
but
metal
alloy
nanoparticles,
along
current
uses
other
supporting
they
conjugated
with,
contributes
significance
work.
Focusing
on
extrapolated
results
over
potentials,
densities
production
rates
both
hydrogen
oxygen
throughout
electrolysis
is
utmost
importance.
Notably,
exhibited
low
Tafel
slopes
(35–45
mV/dec),
crucial
traits
such
affirming
electrocatalysts.
Among
nanoparticles
investigated,
suitable
candidates
conjugation
identified.
Collectively,
data
suggests
CQD/metal
nanoparticle
enhance
splitting
process
particularly
underexplored
realm
production.
However,
it
remains
imperative
perform
experimental
procedures
substantiate
proposition
when
feasible.
C – Journal of Carbon Research,
Год журнала:
2024,
Номер
10(1), С. 7 - 7
Опубликована: Янв. 8, 2024
Graphene
quantum
dot
(GQD)
is
a
new
type
of
carbon
nanometer
material.
In
addition
to
the
excellent
properties
graphene,
it
superior
due
limit
effect
and
edge
effect.
Because
its
advantages
such
as
water
solution,
strong
fluorescent,
small
size,
low
biological
toxicity,
has
important
application
potential
in
various
fields,
especially
sensors
biomedical
areas,
which
are
mainly
used
optical
electrical
well
imaging
tumor
therapy.
addition,
GQDs
have
very
characteristics,
properties.
There
many
preparation
methods,
divided
into
top-down
bottom-up
different
disadvantages,
respectively.
modification
methods
include
heterogeneous
doping,
surface
heterogeneity,
etc.
still
challenges
developing
GQDs.
For
example,
synthesis
steps
hard
conduct,
but
inquiry
continues
deepen,
will
be
revolutionary
materials
future.
this
work,
literature
concerning
research
progress
on
been
reviewed
summarized,
while
key
their
pointed
out,
may
bring
insights
Nanomaterials,
Год журнала:
2025,
Номер
15(5), С. 376 - 376
Опубликована: Фев. 28, 2025
Methyl
orange
(MO)
is
an
organic
synthetic
dye
widely
used
in
laboratory
and
industrial
applications.
In
settings,
it
serves
as
acid-base
indicator
due
to
its
distinct
color
change
both
acidic
alkaline
environments.
Industrially,
primarily
utilized
the
textile
industry
for
ultraviolet
(UV)
absorption
properties.
However,
discharge
leakage
of
methyl
into
environment
can
cause
severe
ecological
damage
pose
potential
carcinogenic
teratogenic
risks
human
health.
Therefore,
detecting
quantifying
concentration
various
matrices
crucial.
This
study
reports
synthesis
graphene
quantum
dots
(GQDs)
from
peel
a
precursor,
using
ethanol
dimethylformamide
(DMF)
solvents.
Cyan
(c-GQDs)
yellow
(y-GQDs)
were
synthesized
through
bottom-up
hydrothermal
method.
The
difference
attributed
redshift
caused
by
varying
ratio
pyridine
nitrogen
pyrrole
nitrogen.
These
GQDs
exhibited
notable
optical
properties,
with
c-GQDs
emitting
cyan
fluorescence
y-GQDs
under
UV
light.
To
investigate
quenching
effects,
nine
commonly
dyes
tested,
all
found
quench
y-GQDs,
having
most
significant
effect.
peel-derived
presence
poor
dispersion
DMF
solution.
Additionally,
possess
high
specific
surface
area,
abundant
functional
groups,
excellent
electronic
conductivity,
which
contribute
their
effective
performance.
average
thickness
(the
vertical
dimension
substrate
upwards)
was
3.51
nm,
confirming
graphene-like
structure.
They
emitted
within
wavelength
range
450-530
nm.
Notably,
linear
correlation
between
intensity
(regression
coefficient
=
0.9954),
indicating
sensing
materials
pollutant
detection.
Abstract
Fluorescent
polymer
particles
have
witnessed
an
increasing
interest
in
recent
years,
owing
to
their
fascinating
physicochemical
properties
as
well
wide‐ranging
applications.
In
this
review,
the
state‐of‐the‐art
research
progress
of
fluorescent
past
five
years
is
summarized.
First,
synthesis
protocols
for
particles,
including
emulsion
polymerization,
precipitation
dispersion
suspension
nanoprecipitation,
self‐assembly,
and
post‐polymerization
modification,
are
presented
detail.
Then,
applications
resulting
beguiling
anticounterfeiting,
chemical
sensing,
biomedicine,
illustrated.
Finally,
challenges
opportunities
that
exist
field
pointed
out.
This
review
aims
offer
important
guidance
stimulate
more
attention
rapidly
developing
field.
