Journal of Controlled Release, Год журнала: 2024, Номер 375, С. 331 - 345
Опубликована: Сен. 17, 2024
Язык: Английский
Journal of Controlled Release, Год журнала: 2024, Номер 375, С. 331 - 345
Опубликована: Сен. 17, 2024
Язык: Английский
Journal of Materials Chemistry C, Год журнала: 2023, Номер 12(5), С. 1609 - 1624
Опубликована: Дек. 22, 2023
In recent years, bismuth-based semiconductors have become a research hotspot in the new semiconductor field due to their unique optical and electronic properties.
Язык: Английский
Процитировано
25Journal of Colloid and Interface Science, Год журнала: 2024, Номер 662, С. 171 - 182
Опубликована: Фев. 8, 2024
Язык: Английский
Процитировано
13Advanced Healthcare Materials, Год журнала: 2024, Номер unknown
Опубликована: Сен. 5, 2024
Abstract Sonodynamic therapy (SDT) represents a promising, noninvasive, and precise treatment modality for tumors, demonstrating significant potential in clinical applications. However, the efficiency of sonosensitizers generating reactive oxygen species (ROS) is often limited by rapid electron‐hole recombination. In this study, BiF 3 @BiOI synthesized via co‐precipitation method, followed in‐situ reduction to decorate it with Pt nanoparticles, resulting @BiOI@Pt‐PVP (BBP) nanocomposite enhancing SDT efficacy. The formation heterojunction enhances charge separation ability. decoration nanoparticles narrows bandgap alters band positions Fermi level BBP, which can effectively mitigate recombination pairs facilitate cascade reaction ROS, thereby improving ROS generation ultrasound excitation. Additionally, bismuth ions BBP generated holes consume glutathione, exacerbating cellular oxidative damage, triggering PANoptosis ferroptosis. Furthermore, demonstrate peroxidase‐like activity, catalyzing endogenous hydrogen peroxide oxygen. These functions are helpful against tumors alleviating hypoxic conditions, reshaping microenvironment, modulating immune cell infiltration capacity, efficacy immunotherapy. dual strategy forming heterojunctions sensitization noble metals sono‐catalytic therapy‐induced activation tumor treatment.
Язык: Английский
Процитировано
10Coordination Chemistry Reviews, Год журнала: 2024, Номер 523, С. 216282 - 216282
Опубликована: Окт. 22, 2024
Язык: Английский
Процитировано
10Inorganics, Год журнала: 2025, Номер 13(3), С. 71 - 71
Опубликована: Фев. 26, 2025
As a non-invasive modality, sonodynamic therapy (SDT) offers several advantages in cancer treatment, including deep tissue penetration and precise spatiotemporal control, resulting from the interplay between low-intensity ultrasound sonosensitizers. Piezoelectric materials, known for their remarkable capacity of interconversion mechanical electrical energy, have garnered considerable attention biomedical applications, which can serve as pivotal sonosensitizers SDT. These materials generate internal electric fields via ultrasound-induced deformation, modulates alteration charge carriers, thereby initiating surface redox reactions to reactive oxygen species (ROS) realizing therapeutic efficacy This review provides an in-depth exploration piezoelectric utilized SDT, with particular emphasis on recent innovations, elucidation underlying mechanisms, optimization strategies advanced materials. Furthermore, incorporation immunotherapy, photodynamic, chemodynamic, chemotherapy is explored, emphasizing potential enhance outcomes. By examining basic principles effect its contributions this sheds light promising applications oncology. It also highlights future directions improving these expanding clinical utility tumor therapy.
Язык: Английский
Процитировано
2Journal of Colloid and Interface Science, Год журнала: 2024, Номер 679, С. 214 - 223
Опубликована: Сен. 29, 2024
Язык: Английский
Процитировано
7Advanced Science, Год журнала: 2025, Номер unknown
Опубликована: Фев. 8, 2025
Hydrogen therapy has shown new potential in cancer treatment, particularly high-pressure and hypoxic areas, where it demonstrates the ability to alter tumor microenvironment regulate metabolism. disrupts mitochondrial function of cells, interferes with their energy metabolism, ultimately leads depletion apoptosis. In this study, a sonocatalyst (BPM), is designed generate hydrogen oxygen situ within tumors, further enhancing therapeutic efficacy. The mesocrystalline structure BPM, composed bismuth fluoride, polyoxometalates, molybdenum carbide, significantly improves charge separation electron transfer efficiency under ultrasound irradiation, resulting an efficient water-splitting reaction. By simultaneously generating depleting glutathione, BPM effectively triggers oxidative stress alleviates hypoxia, thereby disrupting inhibiting metabolism cells. Additionally, enhances antitumor immune responses by promoting dendritic cell maturation, activating T lymphocytes, polarizing macrophages toward M1 phenotype, reversing immunosuppressive state microenvironment. results indicate that holds for gas-immunotherapy combination treatments, offering multifunctional strategy improve outcomes.
Язык: Английский
Процитировано
1Nano Letters, Год журнала: 2025, Номер unknown
Опубликована: Март 6, 2025
Biofilms significantly impede the efficacy of conventional antimicrobial agents, particularly in multidrug-resistant (MDR) infections. In this work, we developed a size-adaptive, bismuth-based nanomicrobicide encapsulated with neutrophil membranes (Bi2S3/SNP@CM), designed to selectively generate nitric oxide (NO) within acidic biofilms under near-infrared (NIR) irradiation. The nanomicrobicide's adaptive size ensures deeper biofilm penetration and accumulation, while membrane coating enhances biocompatibility targeting at infection sites. Upon NIR irradiation, localized heating NO release synergistically eradicate MDR biofilms. Furthermore, interactions between glutathione, as well reactions ROS, disrupt intracellular redox balance, further amplifying antibacterial efficacy. This innovative design affords promising for effectively treating
Язык: Английский
Процитировано
1Nano Today, Год журнала: 2025, Номер 62, С. 102714 - 102714
Опубликована: Март 15, 2025
Язык: Английский
Процитировано
1Journal of environmental chemical engineering, Год журнала: 2025, Номер unknown, С. 116428 - 116428
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
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