Cerium dioxide nanozyme doped hybrid hydrogel with antioxidant and antibacterial abilities for promoting diabetic wound healing

Chemical Engineering Journal, Год журнала: 2024, Номер 497, С. 154517 - 154517

Опубликована: Авг. 3, 2024

Язык: Английский

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Glucose and pH dual-responsive hydrogels with antibacterial, reactive oxygen species scavenging, and angiogenesis properties for promoting the healing of infected diabetic foot ulcers

Acta Biomaterialia, Год журнала: 2024, Номер unknown

Опубликована: Окт. 1, 2024

Язык: Английский

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Quaternized chitosan-based biomimetic nanozyme hydrogels with ROS scavenging, oxygen generating, and antibacterial capabilities for diabetic wound repair

Carbohydrate Polymers, Год журнала: 2024, Номер 348, С. 122865 - 122865

Опубликована: Окт. 18, 2024

Язык: Английский

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Algae-inspired chitosan-pullulan-based multifunctional hydrogel for enhanced wound healing

Carbohydrate Polymers, Год журнала: 2024, Номер 347, С. 122751 - 122751

Опубликована: Сен. 15, 2024

Язык: Английский

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Emerging strategies for nitric oxide production and their topical application as nanodressings to promote diabetic wound healing

Journal of Nanobiotechnology, Год журнала: 2025, Номер 23(1)

Опубликована: Янв. 29, 2025

The challenges associated with prolonged healing or non-healing of chronic diabetic wounds contribute significantly to the increased incidence lower limb amputation. A pivotal factor in impediment is reduced production endogenous nitric oxide (NO) due hyperglycemic microenvironment typical diabetes. While both and exogenous NO have been shown promote process wounds, direct application wound management limited its gaseous nature risk explosive release. This review summarizes recent advances nanodressings incorporating donors treatment detailing specific conditions under which these facilitate release, a focus on beneficial effects NO, strategies for supplementation, encountered clinical translation as clinically viable nanomedicine context improving healing.

Язык: Английский

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A biomimetic endothelial glycocalyx-like hydrogel armored non-glutaraldehyde bioprosthetic valve to resist the thrombosis, calcification and oxidative stress and modulate the immune responses

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 161010 - 161010

Опубликована: Фев. 1, 2025

Язык: Английский

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Advancements in Wound Management: Microenvironment-Sensitive Bioactive Dressings with On-Demand Regulations for Diabetic Wounds

Engineering, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

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Endogenous/exogenous stimuli‐responsive smart hydrogels for diabetic wound healing

Aggregate, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 6, 2024

Abstract Diabetes significantly impairs the body's wound‐healing capabilities, leading to chronic, infection‐prone wounds. These wounds are characterized by hyperglycemia, inflammation, hypoxia, variable pH levels, increased matrix metalloproteinase activity, oxidative stress, and bacterial colonization. complex conditions complicate effective wound management, prompting development of advanced diabetic care strategies that exploit specific characteristics such as acidic pH, high glucose stress trigger controlled drug release, thereby enhancing therapeutic effects dressings. Among solutions, hydrogels emerge promising due their stimuli‐responsive nature, making them highly for managing these The latest advancements in mono/multi‐stimuli‐responsive smart showcase superiority potential healthcare materials, highlighted relevant case studies. However, traditional dressings fall short meeting nuanced needs wounds, adjustable adhesion, easy removal, real‐time status monitoring, dynamic release adjustment according wound's conditions. Responsive represent a significant leap forward proficient sensing responding environment, offering more targeted approach treatment. This review highlights recent dressing, delivery, emphasizing role improving healing. It addresses ongoing challenges future directions, aiming guide clinical adoption.

Язык: Английский

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Antibacterial and antioxidant supramolecular nanocomposite hydrogel dressings with angiogenesis and photo-thermal effect for multidrug‐resistant bacterial infected wound healing

Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 156381 - 156381

Опубликована: Окт. 1, 2024

Язык: Английский

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Nanozymes meet hydrogels: Fabrication, progressive applications, and perspectives

Advances in Colloid and Interface Science, Год журнала: 2025, Номер 338, С. 103404 - 103404

Опубликована: Янв. 23, 2025

Язык: Английский

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