Perspectives in Ecology and Conservation,
Год журнала:
2024,
Номер
22(3), С. 250 - 259
Опубликована: Июль 1, 2024
Among
the
several
noxious
characteristics
of
Persistent
Organic
Pollutants
(POPs)
is
a
low
environmental
degradation
rate,
as
they
remain
in
environment
for
decades.
One
measures
adopted
to
mitigate
contamination
imposition
bans
and
restrictions
chemical
compounds.
But
are
being
efficient
reduce
amount
such
chemicals
environment?
In
this
systematic
review,
we
analyzed
efficacy
banning
POPs
using
bats
biomonitors
terrestrial
habitats.
Although
provide
relevant
ecosystem
services,
these
animals
highly
exposed
organic
pollutants
due
their
feeding
behavioral
habits.
POP
concentrations
were
observed
biological
tissues
genus
Myotis
(United
States),
with
levels
decreasing
over
years
since
ban.
We
also
noticed
shortage
studies
neotropical
regions,
where
information
gap
on
tropical
systems
still
concern
terms
history
intensive
use
toxic
chemicals.
Few
found
emerging
or
recently
included
Stockholm
Convention.
Besides,
specimens
analyses
reviewed
not
separated
by
sex
age,
which
may
conceal
potential
risk
conservation
bat
populations.
recommend
that
future
research
extends
beyond
chronic
include
assessment
trials,
wild
populations
be
affected
long-term,
well
role
economy,
requiring
long-term
studies.
JMIR Public Health and Surveillance,
Год журнала:
2025,
Номер
11, С. e62939 - e62939
Опубликована: Янв. 9, 2025
Background
Although
agricultural
health
has
gained
importance,
to
date,
much
of
the
existing
research
relies
on
traditional
epidemiological
approaches
that
often
face
limitations
related
sample
size,
geographic
scope,
temporal
coverage,
and
range
events
examined.
To
address
these
challenges,
a
complementary
approach
involves
leveraging
reusing
data
beyond
its
original
purpose.
Administrative
databases
(AHDs)
are
increasingly
reused
in
population-based
digital
public
health,
especially
for
populations
such
as
farmers,
who
distinct
environmental
risks.
Objective
We
aimed
explore
reuse
AHDs
addressing
issues
within
farming
by
summarizing
current
landscape
AHD-based
identifying
key
areas
interest,
gaps,
unmet
needs.
Methods
conducted
scoping
review
bibliometric
analysis
using
PubMed
Web
Science.
Building
upon
previous
reviews
research,
we
comprehensive
literature
search
72
terms
population
AHDs.
identify
hot
spots,
directions,
used
keyword
frequency,
co-occurrence,
thematic
mapping.
also
explored
profile
exposome
mapping
co-occurrences
between
factors
outcomes.
Results
Between
1975
April
2024,
296
publications
across
118
journals,
predominantly
from
high-income
countries,
were
identified.
Nearly
one-third
associated
with
well-established
cohorts,
Agriculture
Cancer
Agricultural
Health
Study.
The
most
frequently
included
disease
registers
(158/296,
53.4%),
electronic
records
(124/296,
41.9%),
insurance
claims
(106/296,
35.8%),
(95/296,
32.1%),
hospital
discharge
(41/296,
13.9%).
Fifty
(16.9%)
studies
involved
>1
million
participants.
broad
exposure
proxies
used,
(254/296,
85.8%)
relied
proxies,
which
failed
capture
specifics
tasks.
Research
remains
underexplored,
predominant
focus
specific
external
exposome,
particularly
pesticide
exposure.
A
limited
have
been
examined,
primarily
cancer,
mortality,
injuries.
Conclusions
increasing
use
holds
major
potential
advance
populations.
However,
substantial
gaps
persist,
low-income
regions
among
underrepresented
subgroups,
women,
children,
contingent
workers.
Emerging
issues,
including
per-
polyfluoroalkyl
substances,
biological
agents,
microbiome,
microplastics,
climate
change,
warrant
further
research.
Major
persist
understanding
various
conditions,
cardiovascular,
reproductive,
ocular,
sleep-related,
age-related,
autoimmune
diseases.
Addressing
overlooked
is
essential
comprehending
risks
faced
communities
guiding
policies.
Within
this
context,
promoting
conjunction
other
sources
(eg,
mobile
social
data,
wearables)
artificial
intelligence
approaches,
represents
promising
avenue
future
exploration.
Cells,
Год журнала:
2024,
Номер
13(10), С. 803 - 803
Опубликована: Май 8, 2024
Recent
evidence
indicates
that
exposure
to
environmental
toxins,
both
short-term
and
long-term,
can
increase
the
risk
of
developing
neurological
disorders,
including
neurodegenerative
diseases
(i.e.,
Alzheimer's
disease
other
dementias)
acute
brain
injury
stroke).
For
stroke,
latest
systematic
analysis
revealed
ambient
particulate
matter
is
second
most
frequent
stroke
after
high
blood
pressure.
However,
preclinical
clinical
investigations
on
deleterious
consequences
pollutants
are
scarce.
This
review
examines
recent
how
absorbed
along
digestive
tract
or
inhaled
through
lungs,
affect
host
cellular
response.
We
particularly
address
toxins
immune
response
microbiome
at
gut
lung
barrier
sites.
Additionally,
this
highlights
findings
showing
potential
contribution
an
increased
stroke.
A
better
understanding
biological
mechanisms
underlying
has
mitigate
disorders.
Brain Sciences,
Год журнала:
2024,
Номер
14(2), С. 158 - 158
Опубликована: Фев. 4, 2024
Astrocytes
displaying
reactive
phenotypes
are
characterized
by
their
ability
to
remodel
morphologically,
molecularly,
and
functionally
in
response
pathological
stimuli.
This
process
results
the
loss
of
typical
astrocyte
functions
acquisition
neurotoxic
or
neuroprotective
roles.
A
growing
body
research
indicates
that
these
astrocytes
play
a
pivotal
role
pathogenesis
amyotrophic
lateral
sclerosis
(ALS),
involving
calcium
homeostasis
imbalance,
mitochondrial
dysfunction,
abnormal
lipid
lactate
metabolism,
glutamate
excitotoxicity,
etc.
review
summarizes
characteristics
astrocytes,
ALS,
recent
advancements
astrocyte-targeting
strategies.
