A Review of Fabrication Techniques and Optimization Strategies for Microbial Biosensors DOI Open Access
Eze Frank Ahuekwe,

A.F. Akinyele,

Adam Benson

и другие.

IOP Conference Series Earth and Environmental Science, Год журнала: 2024, Номер 1342(1), С. 012015 - 012015

Опубликована: Май 1, 2024

Abstract Challenges of stability and specificity associated with early generation sensors necessitate the fabrication optimization microbial biosensors. More so, global biosensors market size currently valued at USD25.5 billion in 2021 is expected to grow a compound annual growth rate (CAGR) 7.5% USD36.7 2026. Microbial are bioanalytical systems that integrate microorganisms physical transducer generate signals, thus, aiding identification analytes. The fabricated through series steps comprising microbe selection, immobilization onto matrix, microfabrication, calibration, validation. transducers integrated quantifiable enabling real-time monitoring diversity analytes within food samples. strategies scrutinized, particular focus on integration sundry nanoparticles, such as magnetic, gold, quantum-dot which enhance sensor performance. Distinct advantages offered by promise revolutionize quality assessment via cost-effectiveness, rapid sample testing, ability provide access data. Literature have highlighted certain limitations including interference from complex matrices, instability microorganisms, lifespan. In assessing their economic importance, comparative analysis presented against conventional analytical methods like ELISA, PCR, HPLC; highlighting unique strengths future perspectives potential technology addressing need for continuous challenges, research further improvements biocompatibility processes long-term reusability.

Язык: Английский

Recent Inventions in Additive Manufacturing: Holistic Review DOI Creative Commons
Ismail Fidan,

Orkhan Huseynov,

Mohammad Alshaikh Ali

и другие.

Inventions, Год журнала: 2023, Номер 8(4), С. 103 - 103

Опубликована: Авг. 11, 2023

This general review paper presents a condensed view of recent inventions in the Additive Manufacturing (AM) field. It outlines factors affecting development and commercialization via research collaboration discusses breakthroughs materials AM technologies their integration with emerging technologies. The explores impact across various sectors, including aerospace, automotive, healthcare, food, construction industries, since 1970s. also addresses challenges future directions, such as hybrid manufacturing bio-printing, along socio-economic environmental implications. collaborative study provides concise understanding latest AM, offering valuable insights for researchers, practitioners, decision makers diverse industries institutions.

Язык: Английский

Процитировано

87

Printing the Future Layer by Layer: A Comprehensive Exploration of Additive Manufacturing in the Era of Industry 4.0 DOI Creative Commons

Cristina-Florena Banică,

Alexandru Sover, Daniel-Constantin Anghel

и другие.

Applied Sciences, Год журнала: 2024, Номер 14(21), С. 9919 - 9919

Опубликована: Окт. 30, 2024

In the era of Industry 4.0, 3D printing, or additive manufacturing (AM), has revolutionized product design and across various sectors. This review explores evolution printing technology its impact on industrial innovation, highlighting advancements in aeronautics, automotive industry, biomedicine. Various AM processes, such as binder jetting, direct energy deposition, powder bed fusion, materials like metals, polymers, ceramics, composites, are discussed. Innovations high-speed sintering, continuous liquid interface production, bioprinting demonstrate ongoing advancements. The potential personalized medical applications is emphasized due to flexibility geometry materials. Despite progress, challenges standardization, material quality, recycling, sustainability, economic feasibility hinder widespread adoption. Overcoming these crucial for optimizing technologies, ensuring high-quality, efficient, affordable production. also addresses future prospects 4D 5D technologies their industries. overview underscores printing’s role shaping within context 5.0, emphasizing human–machine collaboration sustainability.

Язык: Английский

Процитировано

18

Application of 3D- printed hydrogels in wound healing and regenerative medicine DOI Creative Commons
Milena Deptuła, Małgorzata Zawrzykraj, Justyna Sawicka

и другие.

Biomedicine & Pharmacotherapy, Год журнала: 2023, Номер 167, С. 115416 - 115416

Опубликована: Сен. 6, 2023

Hydrogels are three-dimensional polymer networks with hydrophilic properties. The modifiable properties of hydrogels and the structure resembling living tissue allow their versatile application. Therefore, increasing attention is focused on use as bioinks for (3D) printing in engineering. Bioprinting involves fabrication complex structures from several types materials, cells, bioactive compounds. Stem cells (SC), such mesenchymal stromal (MSCs) frequently employed 3D constructs. SCs have desirable biological ability to differentiate into various high proliferative capacity. Encapsulating hydrogel constructs enhances reparative abilities improves likelihood reaching target tissues. In addition, created can simulate environment mimic signals. Importantly, immunogenicity scaffolds minimized through patient-specific biocompatibility biodegradability biopolymers. Regenerative medicine taking advantage aforementioned capabilities regenerating tissues- muscle, bones, nerves, heart, skin, cartilage.

Язык: Английский

Процитировано

39

Recent Developments in 3D Bio-Printing and Its Biomedical Applications DOI Creative Commons
Humira Assad,

Arvina Assad,

Ashish Kumar

и другие.

Pharmaceutics, Год журнала: 2023, Номер 15(1), С. 255 - 255

Опубликована: Янв. 11, 2023

The fast-developing field of 3D bio-printing has been extensively used to improve the usability and performance scaffolds filled with cells. Over last few decades, a variety tissues organs including skin, blood vessels, hearts, etc., have all produced in large quantities via bio-printing. These are not only able serve as building blocks for ultimate goal repair regeneration, but they can also be utilized vitro models pharmacokinetics, drug screening, other purposes. To further 3D-printing uses tissue engineering, research on novel, suitable biomaterials quick cross-linking capabilities is prerequisite. A wider acceptable 3D-printed materials still needed, well better printing resolution (particularly at nanoscale range), speed, biomaterial compatibility. aim this study provide expertise most prevalent new an introduction associated approaches that frequently considered by researchers. Furthermore, effort made convey pertinent implementations processes, such providing significant together comprehensive list material selection guidelines, constraints, future prospects.

Язык: Английский

Процитировано

28

The Progress in Bioprinting and Its Potential Impact on Health-Related Quality of Life DOI Creative Commons
Antoniya Yaneva, Dobromira Shopova, Desislava Bakova

и другие.

Bioengineering, Год журнала: 2023, Номер 10(8), С. 910 - 910

Опубликована: Авг. 1, 2023

The intensive development of technologies related to human health in recent years has caused a real revolution. transition from conventional medicine personalized medicine, largely driven by bioprinting, is expected have significant positive impact on patient's quality life. This article aims conduct systematic review bioprinting's potential health-related A literature search was conducted accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. comprehensive undertaken using PubMed, Scopus, Google Scholar, ScienceDirect databases between 2019 2023. We identified some most benefits bioprinting improve life: part production; saving millions lives; reducing rejection risks after transplantation; accelerating process skin tissue regeneration; homocellular model generation; precise fabrication accurate specifications; eliminating need organs donor, thus patient waiting time. In addition, these advances greatly benefit cancer treatment other research, offering medical solutions tailored each individual that could increase chance survival significantly their overall well-being. Although advancements are still research stage, encouraging results scientific studies suggest they verge being integrated into treatment. progress power revolutionize healthcare, promising profound improving life potentially transforming field healthcare.

Язык: Английский

Процитировано

26

Nanomaterials-Based Hybrid Bioink Platforms in Advancing 3D Bioprinting Technologies for Regenerative Medicine DOI
Dilip Kumar Chandra, Rui L. Reis, Subhas C. Kundu

и другие.

ACS Biomaterials Science & Engineering, Год журнала: 2024, Номер 10(7), С. 4145 - 4174

Опубликована: Июнь 1, 2024

3D bioprinting is recognized as the ultimate additive biomanufacturing technology in tissue engineering and regeneration, augmented with intelligent bioinks bioprinters to construct tissues or organs, thereby eliminating stipulation for artificial organs. For of soft tissues, such kidneys, hearts, other human body parts, formulations bioink enhanced bioinspired rheological mechanical properties were essential. Nanomaterials-based hybrid have potential overcome above-mentioned problem require much attention among researchers. Natural synthetic nanomaterials carbon nanotubes, graphene oxides, titanium nanosilicates, nanoclay, nanocellulose, etc. their blended been used various benefitted bioprintability, biocompatibility, biodegradability. A limited number articles published, requirement pushed us write this review. We reviewed, explored, discussed nanocomposite-based technology, properties, natural, synthetic, nanomaterial-based bioinks, including applications challenges, limitations, ethical considerations, solution future perspective, technological advancement efficient cost-effective methods regeneration healthcare.

Язык: Английский

Процитировано

10

Engineered biomimetic micro/nano-materials for tissue regeneration DOI Creative Commons

Feng Han,

Qingchen Meng,

En Xie

и другие.

Frontiers in Bioengineering and Biotechnology, Год журнала: 2023, Номер 11

Опубликована: Июль 4, 2023

The incidence of tissue and organ damage caused by various diseases is increasing worldwide. Tissue engineering a promising strategy tackling this problem because its potential to regenerate or replace damaged tissues organs. biochemical biophysical cues biomaterials can stimulate induce biological activities such as cell adhesion, proliferation differentiation, ultimately achieve repair regeneration. Micro/nano materials are special type biomaterial that mimic the microstructure on microscopic scale due precise construction, further providing scaffolds with specific three-dimensional structures guide cells. study application biomimetic micro/nano-materials have greatly promoted development engineering. This review aims provide an overview different types micro/nanomaterials, their preparation methods in

Язык: Английский

Процитировано

22

Biologicalisation in manufacturing – Current state and future trends DOI
Konrad Wegener,

Oliver Damm,

Simon Harst

и другие.

CIRP Annals, Год журнала: 2023, Номер 72(2), С. 781 - 807

Опубликована: Янв. 1, 2023

Язык: Английский

Процитировано

19

Applications of 3D Bioprinting Technology to Brain Cells and Brain Tumor Models: Special Emphasis to Glioblastoma DOI Creative Commons
Ilkay Irem Ozbek, Hale Saybaşılı, Kutlu Ö. Ülgen

и другие.

ACS Biomaterials Science & Engineering, Год журнала: 2024, Номер 10(5), С. 2616 - 2635

Опубликована: Апрель 26, 2024

Primary brain tumor is one of the most fatal diseases. The malignant type among them, glioblastoma (GBM), has low survival rates. Standard treatments reduce life quality patients due to serious side effects. Tumor aggressiveness and unique structure render removal tumors development new therapies challenging. To elucidate characteristics examine their response drugs, realistic systems that mimic environment cellular crosstalk are desperately needed. In past decade, 3D GBM models have been presented as excellent platforms they allowed investigation phenotypes testing innovative therapeutic strategies. scope, bioprinting technology offers utilities such fabricating bioprinted structures in a layer-by-layer manner precisely controlled deposition materials cells, can be integrated with other technologies like microfluidics approach. This Review covers studies investigated models, especially using techniques essential parameters affect result study frequently used physical hydrogel, conditions, cross-linking methods, characterization techniques.

Язык: Английский

Процитировано

8

4D printing polymeric biomaterials for adaptive tissue regeneration DOI
Zhe Wang, Duo Ma, Juan Liu

и другие.

Bioactive Materials, Год журнала: 2025, Номер 48, С. 370 - 399

Опубликована: Фев. 22, 2025

Язык: Английский

Процитировано

1