Expert Review of Medical Devices,
Год журнала:
2023,
Номер
20(7), С. 557 - 573
Опубликована: Май 25, 2023
Peri-implantitis
is
the
leading
cause
of
dental
implant
loss
and
initiated
by
a
polymicrobial
dysbiotic
biofilm
formation
on
surface.
The
destruction
peri-implant
tissue
host
immune
response
low
effectiveness
surgical
or
non-surgical
treatments
highlight
need
for
new
strategies
to
prevent,
modulate
and/or
eliminate
Currently,
several
surface
modifications
have
been
proposed
using
biomolecules,
ions,
antimicrobial
agents,
topography
alterations.Initially,
this
review
provides
an
overview
etiopathogenesis
host-
material-dependent
modulating
factors
disease.
In
addition,
critical
discussion
about
modification
mechanisms
techniques
employed
modify
titanium
material
provided.
Finally,
we
also
considered
future
perspectives
development
surfaces
narrow
bridge
between
idea
product
favor
clinical
application
possibility.Antimicrobial
demonstrated
effective
results;
however,
there
no
consensus
best
strategy
in-depth
information
safety
longevity
effect.
Modified
display
recurring
challenges
such
as
short-term
effectiveness,
burst
release
drugs,
cytotoxicity,
lack
reusability.
Stimulus-responsive
seem
be
promising
controlled
precise
effect,
research
should
focus
technology
study
it
from
models
that
better
mimic
conditions.
Abstract
Dental
implants
are
the
most
common
therapeutic
approach
for
resolving
tooth
loss
and
damage.
Despite
technical
advances
in
treatment,
implant
failure
rates
can
be
as
high
23%
with
major
cause
of
peri‐implantitis:
a
multi‐species
bacterial
infection.
With
an
annual
growth
rate
placements
8.78%
per
annum,
caused
by
infection
is
significant
oral
general
health
issue.
The
rise
antibiotic
resistance
bacteria
further
adds
pressure
to
failure;
thus,
there
need
adjunctive
therapy
improve
outcomes.
Due
broad
spectrum
activity
low
risk
inducing
resistance,
peptide
antibiotics
emerging
promising
coating
material
reduce/prevent
peri‐implantitis
dental
success
rates.
In
this
review,
we
summarised
current
strategies
antimicrobial
peptides
(AMPs)
onto
surfaces
multi‐functional
properties
enhance
osteoblast
prevent
infections.
This
review
compared
recent
reported
literature
on
AMPs,
which
will
provide
overview
using
AMPs
insights
future
clinical
applications.
Applied Sciences,
Год журнала:
2022,
Номер
12(7), С. 3250 - 3250
Опубликована: Март 23, 2022
Peri-implant
infections
are
the
most
common
complications
related
to
placement
of
dental
implants.
There
many
microbial
similarities
between
peri-implantitis
and
periodontitis
but
due
current
laboratory
techniques
there
just
as
differences.
This
review
was
performed
assess
changes
in
oral
microbiota
at
sites
with
peri-implant
disease,
according
state
art.
The
presents
a
lower
quality
than
periodontal
microbiota,
becoming
increasingly
complex
it
progresses
from
mucositis
peri-implantitis.
difference
detected
is
primarily
whole
bacterial
populations,
rather
specific
taxa.
use
probiotics
could
support
reduction
pockets,
association
mechanical
debridement,
their
mechanism
action
competitive
inhibition
for
adhesion
sites.
represents
qualitatively
inferior
quantitatively
superior
ecosystem
some
genera
compared
showing
that
progression
healthy
causes
composition
absence
disease-causing
bacteria.
Transcriptomics
provide
useful
information
prevention,
diagnosis,
therapy
pathology
through
knowledge
virulence
factors.
Microorganisms,
Год журнала:
2022,
Номер
10(12), С. 2413 - 2413
Опубликована: Дек. 6, 2022
The
oral
cavity
presents
a
highly
diverse
community
of
microorganisms
due
to
the
unique
environmental
conditions
for
microbial
adhesion
and
growth
[...].
Heliyon,
Год журнала:
2023,
Номер
9(6), С. e17457 - e17457
Опубликована: Июнь 1, 2023
In
recent
years,
the
application
of
lasers
for
modifying
surface
topography
dental
biomaterials
has
received
increased
attention.
This
review
paper
aims
to
provide
an
overview
current
status
on
utilization
as
a
potential
tool
modification
such
implants,
ceramics,
and
other
materials
used
restorative
purposes.
A
literature
search
was
done
articles
related
use
in
English
language
published
between
October
2000
March
2023
Scopus,
Pubmed
web
science,
relevant
were
reviewed.Lasers
have
been
mainly
implant
(71%),
especially
titanium
its
alloys,
promote
osseointegration.
laser
texturing
also
emerged
promising
technique
reduce
bacterial
adhesion
surfaces.
Currently,
are
being
widely
modifications
improve
osseointegration
peri-implant
inflammation
ceramic
implants
enhance
retention
restorations
tooth.
The
studies
considered
this
seem
suggest
be
more
proficient
than
conventional
methods
modification.
Lasers
can
alter
characteristics
by
creating
innovative
patterns
without
significantly
affecting
their
bulk
properties.
With
advances
technology
availability
newer
wavelengths
modes,
is
field,
with
excellent
future
research.
ACS Biomaterials Science & Engineering,
Год журнала:
2023,
Номер
9(6), С. 2970 - 2990
Опубликована: Май 15, 2023
Implant
surface
modification
can
improve
osseointegration
and
reduce
peri-implant
inflammation.
surfaces
are
modified
with
metals
because
of
their
excellent
mechanical
properties
significant
functions.
Metal
is
divided
into
metal
ions
nanoparticle
modification.
These
two
methods
function
by
adding
a
finishing
to
the
implant,
both
play
role
in
promoting
osteogenic,
angiogenic,
antibacterial
properties.
Based
on
this,
nanostructural
changes
confer
stronger
cellular
affinity
implant
surface.
The
current
paper
reviews
forms,
mechanisms,
applications
nanoparticles
ion
modifications
provide
foundation
for
implants.
Journal of Materials Research and Technology,
Год журнала:
2024,
Номер
29, С. 5464 - 5472
Опубликована: Март 1, 2024
Surface
texturing
is
widely
investigated
for
the
modulation
of
surface
properties
and
biological
response
implantable
materials.
Laser
a
green
technology
obtainment
specific
patterns
without
employment
toxic
chemicals.
In
present
research,
picosecond
laser
treatment
was
applied
to
commercially
pure
titanium
Ti6Al4V
alloy
aligned
grooves
characterized
by
micrometric
width
spacing
but
submicrometric
depth
promote
fibroblast
alignment
discourage
bacterial
adhesion.
topography
roughness
laser-textured
surfaces
were
using
confocal
microscopy,
contact
profiler,
Scanning
Electron
Microscopy.
Zeta
potential
titration
curves
angle
measurements
used
investigation
charge
wettability,
while
X-Ray
Diffraction
employed
crystallographic
characterization.
Finally,
(fibroblast
adhesion
adhesion)
assessed.
Similar
results
obtained
on
Ti
Ti6Al4V.
Grooves
with
designed
features
(about
15
μm
spaced
0.2μ
deep)
treated
had
complex
micro-
nano-scale
morphology
which
reduced
wettability.
No
evident
chemical
modification
occurred.
The
biocompatible
guidance
effect
human
fibroblasts.
anti-adhesive
action
bacteria
(Staphylococcus
aureus).
Coatings,
Год журнала:
2024,
Номер
14(3), С. 256 - 256
Опубликована: Фев. 21, 2024
During
surgery
and
after,
pathogens
can
contaminate
indwelling
implanted
medical
devices,
resulting
in
serious
infections.
Microbial
colonization,
infection,
later
biofilm
formation
are
major
complications
associated
with
the
use
of
implants
represent
risk
factors
implant
failure.
Despite
fact
that
aseptic
antimicrobial
medications
lower
systemic
antibiotic
result
a
loss
efficacy,
increased
tissue
toxicity,
development
drug-resistant
diseases.
This
work
explores
advancements
coatings
for
head-related
implantable
addressing
critical
issue
infection
prevention.
It
emphasizes
significance
these
reducing
microbial
colonization
highlights
various
techniques
materials
used
creating
effective
surfaces.
Moreover,
this
article
presents
comprehensive
overview
current
strategies
future
directions
coating
research,
aiming
to
improve
patient
outcomes
by
preventing
implant-associated
