International Journal of Adolescence and Youth,
Год журнала:
2024,
Номер
29(1)
Опубликована: Дек. 3, 2024
This
study
determined
the
Quality
of
life
Palestinian
university
students
and
its
associated
factors.
A
total
173
were
included
in
this
cross-sectional
study.
The
collected
data
were;
QoL,
lifestyle,
dietary
pattern,
demographic
data.
results
revealed,
physical
domain
was
with
younger
age,
screen
time
activity,
while
environmental
domain.
Students'
sleep
problems
significantly
lower
QoL
scores
both
psychological
domains.
Less
studying,
napping
during
days
more
family
income
improved
QoL.
In
conclusion,
sociodemographic
style
factors
students'
Exploring
that
influence
will
aid
development
supportive
programmes
policies
to
improve
QOL
shape
their
country's
future.
further
effort
is
needed
establish
promote
knowledge
about
lifestyle
among
students.
Abstract
Age-related
cognitive
impairment
and
dementia
pose
a
significant
global
health,
social,
economic
challenge.
While
Alzheimer’s
disease
(AD)
has
historically
been
viewed
as
the
leading
cause
of
dementia,
recent
evidence
reveals
considerable
impact
vascular
(VCID),
which
now
accounts
for
nearly
half
all
cases.
The
Mediterranean
diet—characterized
by
high
consumption
fruits,
vegetables,
whole
grains,
fish,
olive
oil—has
widely
recognized
its
cardiovascular
benefits
may
also
reduce
risk
decline
dementia.
To
investigate
protective
effects
diet
on
we
conducted
systematic
literature
review
using
PubMed,
Web
Science,
Google
Scholar,
focusing
studies
published
between
2000
2024.
included
in
meta-nalysis
examined
adherence
to
incidence
AD.
We
applied
random-effects
model
calculate
pooled
hazard
ratios
(HRs)
with
95%
confidence
intervals
(CIs)
assessed
heterogeneity
through
I
-square
statistics.
Forest
plots,
funnel
Z
-score
plots
were
used
visualize
study
outcomes.
Of
324
full-text
records
reviewed,
23
met
inclusion
criteria.
combined
HR
among
those
adhering
was
0.82
(95%
CI
0.75–0.89);
0.89
0.83–0.95);
AD,
0.70
0.60–0.82),
indicating
substantial
effects.
Significant
observed
across
studies,
though
suggested
sufficient
sample
sizes
support
reliable
conclusions
each
condition.
In
conclusion,
this
meta-analysis
confirms
that
is
associated
an
11–30%
reduction
age-related
disorders,
including
impairment,
These
findings
underscore
diet’s
potential
central
element
neuroprotective
public
health
strategies
mitigate
promote
healthier
aging.
Nutrients,
Год журнала:
2025,
Номер
17(3), С. 577 - 577
Опубликована: Фев. 5, 2025
Background/Objectives:
With
the
increasing
life
expectancy
and,
as
a
result,
aging
of
global
population,
there
has
been
rise
in
prevalence
chronic
conditions,
which
can
significantly
impact
individuals’
health-related
quality
life,
multidimensional
concept
that
comprises
an
individual’s
physical,
mental,
and
social
wellbeing.
While
balanced,
nutrient-dense
diet,
such
Mediterranean
is
widely
recognized
for
its
role
disease
prevention,
particularly
reducing
risk
cardiovascular
diseases
certain
cancers,
potential
benefits
extend
beyond
these
well-known
effects,
showing
promise
improving
physical
mental
wellbeing,
promoting
life.
Methods:
A
systematic
search
scientific
literature
electronic
databases
(Pubmed/Medline)
was
performed
to
identify
potentially
eligible
studies
reporting
on
relation
between
adherence
diet
published
up
December
2024.
Results:
total
28
were
included
this
review,
comprising
13
conducted
among
general
population
15
involving
various
types
patients.
Overall,
most
showed
significant
association
HRQoL,
with
results
retrieved
domains
suggesting
seems
play
relevant
both
people
affected
by
conditions
inflammatory
basis.
Conclusions:
Adherence
provides
preventing
managing
commonly
associated
populations.
Furthermore,
it
enhances
overall
health
individuals,
ultimately
supporting
more
effective
less
invasive
treatment
approaches
diseases.
Nanomaterials,
Год журнала:
2024,
Номер
14(2), С. 170 - 170
Опубликована: Янв. 12, 2024
Analytical
methods
for
the
early
detection
of
neurodegenerative
biomarker
Parkinson’s
disease
(PD),
α-synuclein,
are
time-consuming
and
invasive,
require
skilled
personnel
sophisticated
expensive
equipment.
Thus,
a
pain-free,
prompt
simple
α-synuclein
biosensor
in
plasma
is
highly
demanded.
In
this
paper,
an
electrochemical
based
on
hierarchical
polyglutamic
acid/ZnO
nanowires
decorated
by
gold
nanoparticles,
assembled
as
nanostars
(NSs),
determination
human
proposed.
ZnO
NSs
were
prepared
chemical
bath
deposition
(CBD)
with
electrodeposited
Au
nanoparticles
(Au
NPs).
Then,
electro-polymerized
glutamic
acid
was
grown
functionalized
anti-α-synuclein.
A
synergistic
enhancement
electrode
sensitivity
observed
when
NPs
embedded
into
NSs.
The
analytical
performance
evaluated
cyclic
voltammetry
(CV)
impedance
spectroscopy
(EIS),
using
Fe(II)(CN)64−/Fe(III)(CN)63−
probe.
charge
transfer
resistance
after
recognition
found
to
be
linear,
concentration
range
0.5
pg·mL−1
10
pg·mL−1,
limit
0.08
good
reproducibility
(5%
variation)
stability
(90%).
also
shown
reliably
discriminate
between
healthy
PD
plasma.
These
results
suggest
that
proposed
provides
rapid,
quantitative
high-sensitivity
result
content
plasma,
represents
feasible
tool
capable
accelerating
non-invasive
identification
disease.
Abstract
Stroke
is
a
leading
cause
of
morbidity
and
mortality
worldwide,
dietary
patterns
have
emerged
as
significant
modifiable
factor
in
stroke
prevention.
The
Mediterranean
diet,
characterized
by
high
intake
fruits,
vegetables,
whole
grains,
nuts,
olive
oil,
fish,
has
been
widely
recognized
for
its
cardiovascular
benefits.
However,
specific
impact
on
risk
requires
further
elucidation.
We
conducted
comprehensive
meta-analysis
30
studies,
including
both
cohort
case–control
designs,
to
evaluate
the
relationship
between
adherence
diet
stroke.
A
systematic
search
was
performed
across
multiple
databases,
random-effects
model
used
estimate
pooled
hazard
ratios
(HRs)
with
95%
confidence
intervals
(CIs).
Heterogeneity
assessed
using
I
2
statistic,
publication
bias
examined
through
funnel
plots
Egger’s
regression
test.
Additionally,
trial
sequential
analysis
determine
adequacy
sample
size.
revealed
reduction
among
individuals
adhering
HR
0.88
(95%
CI:
0.84–0.91).
Notably,
heterogeneity
detected
(
=
34%).
Z-score
plot
from
confirmed
that
sizes
were
sufficient
draw
definitive
conclusions.
potential
identified.
studies
highly
effect
(HR
0.54,
0.4–0.73).
settings
hinted
at
presence
bias,
supported
Our
findings
provide
robust
evidence
supporting
protective
against
Despite
some
cumulative
suggests
promoting
could
serve
an
effective
public
health
strategy
Further
research
recommended
explore
underlying
mechanisms
assess
diet’s
diverse
populations.
Nutrients,
Год журнала:
2025,
Номер
17(8), С. 1351 - 1351
Опубликована: Апрель 15, 2025
Vitamin
D
plays
a
crucial
role
in
the
regulation
of
immune
system,
with
immunomodulatory
effects
that
are
key
prevention
colorectal
cancer
(CRC).
Over
past
decades,
research
has
shown
this
steroid
hormone
impacts
much
more
than
bone
health,
significantly
influencing
responses.
enhances
organ
functions
such
as
spleen
and
lymph
nodes,
boosts
T-cell
activity,
which
is
essential
defending
body
against
tumors.
Additionally,
vitamin
mitigates
inflammatory
responses
closely
linked
to
development,
reducing
inflammation
contributes
CRC.
It
acts
via
receptors
(VDRs)
expressed
on
cells,
modulating
Adequate
levels
influence
gene
expression
related
cell
proliferation,
inhibiting
tumor
development.
also
activates
mechanisms
suppress
survival,
migration,
metastasis.
Low
have
been
associated
an
increased
risk
CRC,
deficiency
correlating
higher
disease
incidence.
Lifestyle
factors,
diet
high
red
meat
calories
but
low
fiber,
fruits,
vegetables,
well
physical
inactivity,
contribute
CRC
risk.
Insufficient
calcium
intake
occurrence
poorer
clinical
outcomes.
Maintaining
optimal
adequate
dietary
preventing
improving
patient
prognosis.
This
review
explores
summarizes
findings
from
randomized
trials
assessing
supplementation
Abstract
Colorectal
cancer
(CRC)
is
a
major
global
health
concern
and
represents
significant
public
challenge
in
Hungary,
where
it
exhibits
some
of
the
highest
morbidity
mortality
rates
European
Union.
The
Mediterranean
diet
has
been
suggested
to
reduce
incidence
CRC,
but
comprehensive
evidence
from
diverse
study
designs
needed
substantiate
this
effect.
A
systematic
literature
search
was
conducted
PubMed,
ClinicalTrials.gov,
CENTRAL,
Web
Science
identify
randomized
controlled
trials
human
clinical
2008
2024
relevant
studies.
Statistical
analysis
performed
using
https://metaanalysisonline.com
web
application
random
effects
model
estimate
pooled
hazard
(HRs).
Forest
plots,
funnel
Z
-score
plots
were
utilized
visualize
results.
We
identified
15
9
case–control
studies,
encompassing
total
2,217,404
subjects.
indicated
that
adherence
significantly
reduced
prevalence
CRC
(HR
=
0.84,
95%
CI
0.78–0.91,
p
<
0.01).
This
protective
effect
consistent
across
sexes,
with
HRs
0.85
(95%
0.75–0.97,
0.01)
for
males
0.88
0.79–0.99,
0.03)
females.
Case–control
studies
specifically
showed
substantial
0.51,
0.38–0.68,
Notable
heterogeneity
observed
yet
priori
information
size
substantially
below
cumulative
sample
size,
ensuring
sufficient
data
reliable
conclusions.
findings
meta-analysis
reinforce
role
against
CRC.
results
will
inform
dietary
interventions
designed
mitigate
risk,
which
are
within
framework
Semmelweis
Study,
an
ongoing
cohort
at
University,
explore
multifaceted
causes
unhealthy
aging
Hungary.
These
aim
practical
patterns
reducing
among
Hungarian
population.
Nutrition Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Май 17, 2024
Abstract
Context
Childhood
and
adolescence
are
periods
of
critical
importance
in
the
development
mental
health
disorders.
The
Mediterranean
diet
(MD)
has
been
linked
to
multiple
positive
outcomes,
including
reduced
incidence
disorders
fewer
psychiatric
symptoms.
Objective
This
study
aimed
investigate
association
between
adherence
an
MD
outcomes
children
adolescents.
Methods
A
systematic
literature
review
was
conducted
original
research
that
explored
relationship
symptoms
or
MD.
search
on
PubMed,
Scopus,
Web
Science,
MEDES,
Dialnet,
Latindex
from
inception
November
2022,
Newcastle-Ottawa
Scale
used
evaluate
quality
studies.
Results
total
13
studies
(6
cross-sectional,
4
case-control,
2
randomized
clinical
trials,
1
longitudinal
cohort)
out
450
met
inclusion
criteria.
3058
adolescents
with
a
mean
age
range
8.6
16.2
years
were
included.
Among
reviewed
studies,
5
(71.42%)
those
looking
at
attention-deficit/hyperactivity
disorder,
(80%)
examining
depression,
(50%)
assessing
anxiety
found
significant
protective
association.
Seven
articles
(53.84%)
be
high
6
(46.15%)
moderate
quality.
Conclusion
Adherence
could
factor
for
child
adolescent
populations.
suggests
promoting
help
prevent
onset
symptoms,
reduce
symptom
severity,
improve
prognosis
young
patients.
Systematic
Review
Registration
PROSPERO
registration
no.
CRD42021276316.
Nutrients,
Год журнала:
2023,
Номер
15(14), С. 3219 - 3219
Опубликована: Июль 20, 2023
The
Mediterranean
diet
(MD)
is
considered
a
model
for
good
health,
and
promoted
worldwide
as
one
of
the
healthiest
dietary
patterns.
Despite
MD’s
health
benefits,
literature
suggests
that
adherence
to
MD
tends
be
in
decline
most
populations
worldwide,
including
those
region.
aim
this
study
was
investigate
MD,
its
main
sociodemographic
lifestyle
factors,
Slovenian
population.
Using
nationwide
cross-sectional
food
consumption
survey
(SI.Menu),
data
were
collected
from
general
questionnaire,
14-item
screener
(14-MEDAS
score),
questionnaire
on
habits
850
adults
elderly
people.
mean
MEDAS
score
total
sample
5.6
(SD
2.1),
indicating
low
among
higher
women
(OR
=
1.534;
95%
Cl
1.156–2.034),
with
university
degree
1.527;
1.098–2.125;
compared
no
degree),
who
lived
suburb
or
city
1.511;
1.016–2.249;
OR
1.568;
1.122–2.191;
village),
non-smokers
1.561;
1.380–1.830;
smokers),
western
part
Slovenia
1.558;
1.170–2.074;
eastern
Slovenia).
Adherence
population
low,
strongly
related
educational
level,
gender,
geographic
region,
place
residence,
smoking
status.
frequency
different
groups
also
closely
related.
Frontiers in Aging Neuroscience,
Год журнала:
2024,
Номер
15
Опубликована: Янв. 25, 2024
Purpose
To
evaluate
the
effect
of
repetitive
transcranial
magnetic
stimulation
(rTMS)
paired
with
cognitive
training
on
function
in
Alzheimer’s
Disease
(AD)
patients.
Methods
PubMed,
The
Cochrane
Library,
Embase,
CINAHL
Complete
(EBSCO),
China
National
Knowledge
Infrastructure
(CNKI)
and
WanFang
Database
were
searched.
risk
bias
was
appraised
through
collaboration
tool.
A
meta-analysis
conducted,
including
an
assessment
heterogeneity.
Results
Ten
studies
comprising
408
participants
included.
addition
rTMS
significantly
improved
overall
cognition
patients
compared
intervention
alone
(
p
<
0.05
for
all
tests).
treatment
also
had
some
continuity,
significant
improvements
within
weeks
after
ended
Conclusion
Repetitive
combined
(rTMS-CT)
is
a
valuable
technique
rehabilitation
AD
It
beneficial
to
improve
ability
restore
their
functional
state.
results
study
may
provide
basis
clinical
providers
implement
interventions
that
facilitate
design
more
rigorous
high-quality
interventions.
Limitations
number
sample
size
our
small.
We
did
not
explore
possible
interactions
between
medications
mood
improvement
due
inadequate
data.
Systematic
review
registration
This
registered
PROSPERO
CRD42023405615.