International Journal for Research in Applied Science and Engineering Technology,
Год журнала:
2024,
Номер
12(3), С. 2179 - 2184
Опубликована: Март 25, 2024
Abstract:
Worldwide,
edible
mushrooms
are
prized
for
their
medical
and
nutraceutical
qualities.
Because
of
high
protein
content,
low
fat
cholesterol
levels,
low-calorie
abundance
vital
vitamins,
they
acknowledged
as
the
new
superfood
future.
This
is
considered
that
only
vegetarian
source
vitamin
D
because
contain
amount
ergosterol
fat-soluble
vitamins.
Limited
information
exists
regarding
composition
fiber,
although
polysaccharides
such
β-glucans
increase
nutritional
value
mushrooms.
Mushrooms
a
fantastic
food
many
pharmacological
qualities,
has
been
noted.
Shiitake
nutrient-dense,
widely
farmed
fungal
plants
possess
various
properties.
The
purpose
this
review
to
compile
most
recent
on
health
advantages
medicinal
uses
shiitake
Frontiers in Materials,
Год журнала:
2024,
Номер
11
Опубликована: Июль 15, 2024
The
escalating
accumulation
of
toxic
wastes
and
biowastes
constitutes
a
critical
environmental
crisis
that
demands
immediate
effective
solutions.
Traditional
waste
treatment
methods,
predominantly
chemical
physical,
are
increasingly
viewed
as
unsustainable,
burdened
by
high
operational
costs
the
risk
generating
secondary
pollutants.
Against
this
backdrop,
bioremediation
emerges
crucial
sustainable
alternative,
utilizing
natural
detoxifying
capabilities
microorganisms.
This
review
article
focuses
on
use
fungal
bacterial
strategies
in
bioremediation,
emphasizing
their
vital
role
degradation,
stabilization,
or
detoxification
We
provide
an
in-depth
analysis
mechanisms
which
fungi
bacteria
break
down
various
contaminants,
presenting
current
snapshot
field’s
state
knowledge.
highlights
recent
innovative
advancements
improve
effectiveness
expand
applicability
technologies.
Moreover,
it
discusses
practical
challenges
scaling
these
solutions
to
meet
global
needs
suggests
directions
for
future
research
implementation.
synthesis
not
only
underscores
significance
microbial
addressing
pressing
problems
but
also
acts
call
action
continued
innovation
management
hazardous
wastes.
Fermentation,
Год журнала:
2024,
Номер
10(6), С. 275 - 275
Опубликована: Май 23, 2024
It
is
widely
known
that
mushrooms
present
several
properties
with
applications
in
the
medicinal
and
pharmaceutical
sectors,
including
antimicrobial,
immunomodulatory,
antioxidant,
hypotensive,
neuroprotective,
anti-inflammatory
activities.
This
article
aims
to
review
examples
of
bioactive
metabolites
responsible
for
those
activities,
such
as
polysaccharides,
phenols
polyphenols,
terpenes,
peptides,
alkaloids,
steroids,
which
are
produced
by
relevant
mushroom
species.
also
discusses
their
production
through
solid-state
fermentation
submerged
fermentation,
well
processes
obtention
extracts
considerations
on
stability
aiming
industrial
applications.
In
addition,
examines
patent
landscape
surrounding
mushroom-derived
bioactives,
shedding
light
intellectual
property
history
innovations
driving
this
field
forward.
Examples
recently
deposited
patents
highlighted,
main
depositors.
China
United
States
major
depositor
countries
(52%
35%
patents,
respectively),
principal
compounds
polysaccharides
alkaloids.
The
provides
insights
into
current
market
landscape,
showcasing
products
available
consumers.
From
dietary
supplements
skincare
formulations,
offerings
reflect
growing
interest
harnessing
health
benefits
bioactives.
RSC Advances,
Год журнала:
2024,
Номер
14(33), С. 23744 - 23771
Опубликована: Янв. 1, 2024
Introduction:
Pharmacotherapeutic
targets
for
breast
cancer
include
the
estrogen
receptor
(ER),
progesterone
(PR),
and
human
epidermal
growth
factor
(EGFR).
Inhibitors
of
these
receptors
could
be
interesting
therapeutic
candidates
treatment
management
(BC).
Aim:
This
study
used
GC-MS
HPLC
to
identify
bioactive
compounds
in
Pleurotus
ostreatus
(P.
ostreatus)
extracts
applied
silico
methods
potent
EGFR,
ER,
PR
inhibitors
from
as
potential
drug
candidates.
Method:
were
chemicals
P.
aqueous
(PO-A),
methanol
(PO-M),
ethanol
(PO-E),
chloroform
(PO-C),
n-hexane
(PO-H).
The
PR,
EGFR
model
optimization
molecular
docking
compounds/control
binding
pocket
simulated
using
AutoDock
Vina
PyRx.
drug-likeness,
pharmacokinetic,
pharmacodynamic
features
prospective
leads
all
anticipated.
Result:
results
indicated
existence
29
PO-A,
36
PO-M
PO-E,
42
PO-C,
22
PO-H
extracts.
With
only
o-tolylamino-acetic
acid
(4-nitro-benzylidene)-hydrazide
(-7.5
kcal
mol-1)
ethanolic
extract
bind
receptor.
on
other
hand,
identified
several
with
higher
affinities
than
control.
Ergotaman-3',6',18-trione
(-8.1
mol-1),
5,10-diethoxy-2,3,7,8-tetrahydro-1H,6H-dipyrrolo[1,2-a:1',2'-d]pyrazine
(-7.8
extract;
(-8.4
had
better
affinity
compared
(-7.7
mol-1).
Likewise,
ergotaman-3',6',18-trione
(-9.7
phenol,
2,4-bis(1,1-dimethyl
ethyl)
(-8.2
control,
gefitinib
(-7.9
regards
EGFR.
None
or
outperformed
control
any
proteins.
Phenols
flavonoids
such
quercetin,
luteolin,
rutin,
chrysin,
apigenin,
ellagic
acid,
naringenin
their
Conclusion:
class
phenols
lead
molecules
due
ability
strongly
proteins'
receptors.
These
showed
promising
drug-like
properties;
they
safe
new
creating
anticancer
medicines.
