Environment & Health,
Год журнала:
2025,
Номер
3(4), С. 425 - 435
Опубликована: Янв. 29, 2025
Conventional
metrics
for
tracking
infectious
diseases,
including
case
and
outbreak
data
syndromic
surveillance,
can
be
resource-intensive,
misleading,
comparatively
slow
with
prolonged
collection,
analysis
authentication.
This
study
examined
the
2022–2023
Respiratory
Syncytial
Virus
(RSV)
season
in
a
contiguous
metropolitan
area
connected
by
an
active
international
land
border,
affording
opportunity
comparison
of
respiratory
virus
spanning
two
independent
public
health
jurisdictions.
Time-lagged
cross
correlation
qualitative
examination
wastewater
signals
showed
that
peak
Detroit
(MI,
USA)
RSV
predated
Windsor
(ON,
Canada)
approximately
5
weeks.
A
strong
positive
relationship
was
observed
between
N-gene
concentrations
hospitalization
rates
Windsor-Essex
(Kendall's
τ
=
0.539,
p
≤
0.001,
Spearman's
ρ
0.713,
0.001)
as
well
0.739,
0.888,
0.001).
demonstrated
surveillance
reveal
regional
differences
infection
dynamics
communities
provide
measure
prevalence
RSV,
underreported
disease.
These
findings
support
use
cost-effective
tool
monitoring
to
enhance
existing
systems
better
inform
disease
mitigation
strategies.
Emerging Microbes & Infections,
Год журнала:
2023,
Номер
12(2)
Опубликована: Июнь 6, 2023
Severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
has
been
detected
in
wastewater.
Wastewater-based
epidemiology
(WBE)
is
a
practical
and
cost-effective
tool
for
the
assessment
controlling
of
pandemics
probably
examining
SARS-CoV-2
presence.
Implementation
WBE
during
outbreaks
not
without
limitations.
Temperature,
suspended
solids,
pH,
disinfectants
affect
stability
viruses
Due
to
these
limitations,
instruments
techniques
have
utilized
detect
SARS-CoV-2.
sewage
using
various
concentration
methods
computer-aided
analyzes.
RT-qPCR,
ddRT-PCR,
multiplex
PCR,
RT-LAMP,
electrochemical
immunosensors
employed
low
levels
viral
contamination.
Inactivation
crucial
preventive
measure
against
disease
2019
(COVID-19).
To
better
assess
role
wastewater
as
transmission
route,
detection,
quantification
need
be
refined.
In
this
paper,
latest
improvements
quantification,
inactivation
are
explained.
Finally,
limitations
future
research
recommendations
thoroughly
described.
Journal of Water and Health,
Год журнала:
2022,
Номер
20(9), С. 1284 - 1313
Опубликована: Авг. 12, 2022
Abstract
Wastewater-based
epidemiology
(WBE)
is
an
unobtrusive
method
used
to
observe
patterns
in
illicit
drug
use,
poliovirus,
and
severe
acute
respiratory
syndrome
coronavirus-2
(SARS-CoV-2).
The
pandemic
need
for
surveillance
measures
have
led
the
rapid
acceleration
of
WBE
research
development
globally.
With
infrastructure
available
monitor
SARS-CoV-2
from
wastewater
58
countries
globally,
there
potential
expand
targets
applications
public
health
protection,
such
as
other
viral
pathogens,
antimicrobial
resistance
(AMR),
pharmaceutical
consumption,
or
exposure
chemical
pollutants.
Some
been
explored
academic
but
are
not
inform
decision-making.
We
reflect
on
current
knowledge
these
identify
barriers
opportunities
expanding
beyond
SARS-CoV-2.
This
paper
critically
reviews
identifies
important
gaps
be
a
useful
tool
health.
It
considers
possible
uses
pathogenic
viruses,
AMR,
chemicals.
summarises
evidence
following:
(1)
presence
markers
stool
urine;
(2)
environmental
factors
influencing
persistence
wastewater;
(3)
methods
sample
collection
storage;
(4)
prospective
detection
quantification;
(5)
reducing
uncertainties;
(6)
further
considerations
use.
Water,
Год журнала:
2024,
Номер
16(9), С. 1220 - 1220
Опубликована: Апрель 25, 2024
Background:
Wastewater-based
epidemiology
(WBE)
has
become
crucial
for
early
microbial
outbreak
detection
and
public
health
surveillance
globally,
underscored
by
the
COVID-19
pandemic.
However,
despite
advancements
in
sampling
analyses,
interpreting
results
estimating
infection
rates
pose
challenges.
Enhancements
sewer
system
engineering,
understanding
wastewater
environment,
addressing
impact
of
environment
on
accuracy
are
needed.
Objective:
This
scoping
review
aims
to
identify
engineering
knowledge
gaps
WBE
guide
future
study
designs.
Design:
Research
“wastewater-based
epidemiology”
involving
“engineering”,
published
between
2015
2023,
was
extracted
from
Scopus
database.
Results:
examines
elements
influencing
WBE’s
precision
reliability,
especially
identifying
measuring
SARS-CoV-2
RNA.
It
identifies
significant
effects
analytical
practices,
wastewater’s
composition
performance.
Conclusions:
calls
further
investigation
into
economical
evaluation
methods
these
factors
enhance
data
normalization
interpretation,
utilizing
existing
treatment
plant
used
control,
which
could
be
a
cost-effective
approach
over
more
expensive
population
biomarkers.
approach,
aside
SARS-CoV-2,
holds
potential
application
broader
number
types
diseases,
as
well
consumption
habits.
