Unleashing the power of silk-based proteins as biomaterials for cutting-edge drug delivery: a comprehensive review DOI

Vishal Kumar Parida,

Kavita Kavita,

Rashmi Arora

и другие.

Journal of Biomaterials Science Polymer Edition, Год журнала: 2024, Номер unknown, С. 1 - 25

Опубликована: Сен. 4, 2024

Silk proteins, viz., sericin, fibroin and their modified forms etc., have been thoroughly researched as natural biopolymers for the development of varied nanomaterials exhibiting diverse biomedical applications. The silk proteins are extracted from cocoons by degumming treatment with soaps, followed dissolution dialysis against water. These exhibit distinct mechanical physicochemical characteristics including biocompatibility, controlled biodegradability, self-assembling traits, chemical modifiability, adaptability, thus making it an ideal drug delivery vehicle. In this regard, protein-derived systems reported efficient carrier to encapsulate stabilize wide variety pharmacological molecules, enzymes, vaccines, even DNA, allowing them remain active a longer period time. Further, different carriers employing these multitude applications include hydrogels, sponges, fibres, scaffolds particulate systems. Additionally, modification has further opened avenues other improved traits hence enormous potential in bioenhanced current article provides holistic information characteristics, types protein-based carriers, fabrication techniques, while emphasizing biomedicine delivery.

Язык: Английский

Synthesis, SAR, and application of JQ1 analogs as PROTACs for cancer therapy DOI
Soumik De, Raghaba Sahu, Shubhendu Palei

и другие.

Bioorganic & Medicinal Chemistry, Год журнала: 2024, Номер 112, С. 117875 - 117875

Опубликована: Авг. 16, 2024

Язык: Английский

Процитировано

2

Silk protein–based smart hydrogels for biomedical applications DOI
Prachi P. Agarwal, Akankshya Kar, Kirthanashri S. Vasanthan

и другие.

Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 265 - 296

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

1

Opportunities and Regulatory Challenges of Functional Foods and Nutraceuticals During COVID-19 Pandemic DOI
Jobin Jose,

Keyidaule Ndang,

Madhusoodhana Ballakkuraya Chethana

и другие.

Current Nutrition & Food Science, Год журнала: 2024, Номер 20(10), С. 1252 - 1271

Опубликована: Март 1, 2024

: The novel Coronavirus has brought global mortality, disruption, and a significant loss of life. A compromised immune system is known risk factor for all viral influenza infections. Due to the perceived “immune-boosting” properties nutraceutical products, sales dietary supplements have grown globally. In recent years, consumers increasingly demanded products rather than curative synthetic medicines preventive therapies coronavirus disease outbreak 2019 (COVID-19). Healthy foods nutraceuticals become daily diet plans consumers. Although there been an increase in demand, no such regulation harmonized process, which stands as barrier approval these products. Therefore, many misbranded spurious are entering market, may harm This article focuses on role functional management COVID-19 also different regulations each country compare similarities differences following countries: India, USA (United States America), EU (European Union), China. comparative study USA, Europe, China shows that difference regarding regulations; however, despite differences, it observed same underlying objective, i.e., ensuring safety by maintaining product quality.

Язык: Английский

Процитировано

1

The Potential of Natural Carotenoids-Containing Sericin of the Domestic Silkworm Bombyx mori DOI Open Access
Sirui Liu, Qing Zhang,

Hanyue Zhou

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(7), С. 3688 - 3688

Опубликована: Март 26, 2024

Sericin derived from the white cocoon of Bombyx mori has been attracting more attention for its utilization in food, cosmetics, and biomedicine. The potential health benefits natural carotenoids humans have also well-established. Some rare strains (B. mori) produce yellow-red cocoons, which endow a carotenoid-containing sericin. We hypothesized that sericin cocoons would exhibit better properties compared with To investigate physicochemical attributes sericin, we bred two silkworm one common ancestor, namely XS7 XS8, exhibited different colors as result inconsistent distribution lutein β-carotene. Compared interaction between molecules resulted unique fluorescence emission at 530, 564 nm. incorporation enhanced antibacterial effect, anti-cancer ability, cytocompatibility, antioxidant suggesting wide-ranging applications biomass material. found differences characteristics, antimicrobial effects, antioxidants XS8 Our work first time suggested application material than frequently used

Язык: Английский

Процитировано

1

Synthesis of melanin-like amino acid surfactant with enzymatic hydrolysates from silk degumming water DOI
Hong Zhou, Yi Tang, Mengqi Han

и другие.

Journal of Biotechnology, Год журнала: 2024, Номер 394, С. 85 - 91

Опубликована: Авг. 23, 2024

Язык: Английский

Процитировано

1

Synthesis, characterization and application of silk sericin-based silver nanocomposites for antibacterial and food coating solutions DOI Creative Commons

Shubhajit Shaw,

Rittick Mondal, Paulami Dam

и другие.

RSC Advances, Год журнала: 2024, Номер 14(45), С. 33068 - 33079

Опубликована: Янв. 1, 2024

The rising demand for fresh and safe food is driving advancements in preservation technologies, with nanoparticles offering a revolutionary solution.

Язык: Английский

Процитировано

1

Versatile Mixed Micellar Pluronic Formulations as Drug Delivery Carriers for Aripiprazole and Carbamazepine – A Comparative Study DOI
Jaspreet Kaur, Pankaj Singla,

Inderpreet Kaur

и другие.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2024, Номер unknown, С. 135997 - 135997

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

1

Development of Eco-Friendly Method for Degumming of Eri Cocoons DOI Creative Commons

Sreenivasa,

Naveen V. Padaki

Textile & Leather Review, Год журнала: 2023, Номер 6, С. 742 - 759

Опубликована: Ноя. 22, 2023

In this study, a new eco-friendly degumming technique was developed for Eri cocoons without any chemicals. A newly eco-Eri process tried at 110 °C, 120 130 °C and 140 temperatures 10, 20 30 min with soft hard water. The novel method compared the existing of viz. Soap-soda along enzymatic method. After degumming, weight loss per cent, changes in fibre surface morphology concerning SEM imaging properties tensile strength elongation were studied. using water removed maximum sericin content (degumming 15.7%) from cocoon shells had optimum efficiency. method, degummed uniformly softened. soap soda resulted 14.5% whereas 13% (12% dosage). Enzymatic significantly reduced but no results found silk fibres observed soap-soda methods. images indicated optimal smoother until damage fibrillation occurred also An condition is better to other methods used presently industry.

Язык: Английский

Процитировано

2

Trends in silk biomaterials DOI
Simone S. Silva, Rui L. Reis, Subhas C. Kundu

и другие.

Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 9 - 39

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0

Exploring the mechanistic role of silk sericin biological and chemical conjugates for effective acute and chronic wound repair and related complications DOI

Esham Nadeem Butt,

Shaukat Ali,

Muhammad Summer

и другие.

Drug Development and Industrial Pharmacy, Год журнала: 2024, Номер 50(7), С. 577 - 592

Опубликована: Июль 2, 2024

Objective The current review is designed to elaborate and reveal the underlying mechanism of sericin its conjugates drug delivery during wounds wound-related issues.

Язык: Английский

Процитировано

0