BioNanoScience, Год журнала: 2024, Номер 14(3), С. 3355 - 3384
Опубликована: Май 21, 2024
Язык: Английский
Frontiers in Pharmacology, Год журнала: 2019, Номер 10
Опубликована: Окт. 25, 2019
In recent years, various nanomaterials have emerged as an exciting tool in cancer theranostics applications due to their multifunctional property and intrinsic molecular aiding effective diagnosis, imaging, successful therapy. However, chemically synthesized nanoparticles several issues related the cost, toxicity effectiveness. this context, bio-inspired (NPs) held edges over conventionally low easy synthesis toxicity. present review article, a detailed overview of has been provided. This includes examples liposomes, lipid nanoparticles, protein inorganic viral nanoparticles. Finally, challenges future scopes these NPs therapy diagnostics are highlighted.
Язык: Английский
Процитировано
184
Advanced Drug Delivery Reviews, Год журнала: 2022, Номер 188, С. 114445 - 114445
Опубликована: Июль 9, 2022
Язык: Английский
Процитировано
174
Seminars in Cancer Biology, Год журнала: 2021, Номер 76, С. 17 - 26
Опубликована: Июнь 25, 2021
Язык: Английский
Процитировано
162
Molecules, Год журнала: 2020, Номер 25(20), С. 4613 - 4613
Опубликована: Окт. 10, 2020
Polyphenols are micronutrients that widely present in human daily diets. Numerous studies have demonstrated their potential as antioxidants and anti-inflammatory agents, for cancer prevention, heart protection the treatment of neurodegenerative diseases. However, due to vulnerability environmental conditions low bioavailability, application food medical fields is greatly limited. Nanoformulations, excellent drug delivery systems, can overcome these limitations maximize pharmacological effects polyphenols. In this review, we summarize biological activities polyphenols, together with systems delivery, including phospholipid complexes, lipid-based nanoparticles, protein-based niosomes, polymers, micelles, emulsions metal nanoparticles. The polyphenol nanoparticles medicine also discussed. Although loading into solves main limitation polyphenolic compounds, there some concerns about toxicological safety after entry body. It therefore necessary conduct toxicity residue analysis on carrier.
Язык: Английский
Процитировано
153
RSC Advances, Год журнала: 2021, Номер 11(40), С. 24722 - 24746
Опубликована: Янв. 1, 2021
Bioinspired metallic nanoparticles (BMN) have revolutionized the biomedical domain and are still developing rapidly. Hence, this review on BMN elaborates properties, biosynthesis, applications, its role in combating SARS-CoV-2.
Язык: Английский
Процитировано
134
Nanomaterials, Год журнала: 2022, Номер 12(7), С. 1102 - 1102
Опубликована: Март 27, 2022
Nanoparticles are currently used for cancer theranostics in the clinical field. Among nanoparticles, gold nanoparticles (AuNPs) attract much attention due to their usability and high performance imaging techniques. The wide availability of biological precursors plant-based synthesized AuNPs allows development large-scale production a greener manner. Conventional therapies, such as surgery chemotherapy, have significant limitations frequently fail produce satisfying results. prolonged circulation time, allow easy modification with ligands detected via cell surface receptors, increase uptake through receptor-mediated endocytosis. To exploit these unique features, studies been carried out on use contrast agents X-ray-based techniques (i.e., computed tomography). As nanocarriers, by nontoxic biocompatible plants deliver therapeutic biomolecules could be stride forward effective treatment various cancers. Fluorescent-plant-based markers, including AuNPs, fabricated using Medicago sativa, Olax Scandens, H. ambavilla, lanceolatum, detecting Moreover, green extracts applied different types solid tumors. However, cytotoxicity primarily depends size, reactivity, area. In this review, benefits materials therapy firstly explained. Then, considering valuable position medicine, application detection is highlighted an emphasis faced NPs drug delivery platforms.
Язык: Английский
Процитировано
132
Journal of Functional Biomaterials, Год журнала: 2021, Номер 12(4), С. 70 - 70
Опубликована: Дек. 3, 2021
Gold nanoparticles (AuNPs) are extremely promising objects for solving a wide range of biomedical problems. The gold production by biological method (“green synthesis”) is eco-friendly and allows minimization the amount harmful chemical toxic byproducts. This review devoted to AuNPs biosynthesis peculiarities using various living organisms (bacteria, fungi, algae, plants). participation biomolecules in synthesis influence size, shapes, capping agents on functionalities described. proposed action mechanisms target cells highlighted. activities “green” (antimicrobial, anticancer, antiviral, etc.) possibilities their further application also discussed.
Язык: Английский
Процитировано
128
Journal of Drug Delivery Science and Technology, Год журнала: 2022, Номер 77, С. 103874 - 103874
Опубликована: Окт. 7, 2022
Язык: Английский
Процитировано
100
Photodiagnosis and Photodynamic Therapy, Год журнала: 2023, Номер 42, С. 103312 - 103312
Опубликована: Янв. 30, 2023
Язык: Английский
Процитировано
85
Frontiers in Oncology, Год журнала: 2022, Номер 12
Опубликована: Апрель 22, 2022
Colorectal cancer (CRC) is one of the most common and reoccurring diseases, as well world's second largest cause mortality. Despite existing preventative, diagnostic, treatment methods, such chemotherapy, number instances rises year after year. As a result, new effective medications targeting specific checkpoints should be developed to combat CRC. Natural compounds, curcumin, have shown significant anti-colorectal characteristics among that can used treat These chemicals are phenolic compounds belong curcuminoids category. Curcumin exerts its anti-proliferative properties against CRC cell lines in vitro vivo via variety mechanisms, including suppression intrinsic extrinsic apoptotic signaling pathways, stoppage cycle, activation autophagy. also has anti-angiogenesis properties. Thus, this review aimed at emphasizing biological effect mode action curcumin on Furthermore, critical role these substances chemoprevention was emphasized.
Язык: Английский
Процитировано
83