Therapeutic Delivery,
Journal Year:
2023,
Volume and Issue:
14(5), P. 357 - 381
Published: May 1, 2023
Breast
cancer
(BC)
is
among
the
most
frequent
malignancies
women
face
around
globe.
Nanotherapeutics
are
constantly
evolving
to
overcome
limitations
of
conventional
diagnostic
and
therapeutic
approaches.
Nanotechnology-based
nanocarriers
have
a
higher
entrapment
efficiency,
low
cytotoxicity,
greater
stability
improved
half-life
than
therapy.
Nano-drug
delivery
systems
pharmacokinetics
pharmacodynamics
parameters
because
nanomeric
size.
Currently,
various
nano-formulations
in
preclinical
clinical
settings
for
breast
cancer,
like
polymeric
nanoparticles,
micelles,
nanobodies,
magnetic
liposomes,
niosomes,
gold-nanoparticles,
dendrimers
carbon-nanotubes.
This
review
highlights
recent
advancement
developing
nano-drug
BC
treatment.
will
open
gateway
researchers
understand
current
approaches
nano-formulation
improving
problems
associated
with
Frontiers in Pharmacology,
Journal Year:
2019,
Volume and Issue:
10
Published: Oct. 25, 2019
In
recent
years,
various
nanomaterials
have
emerged
as
an
exciting
tool
in
cancer
theranostics
applications
due
to
their
multifunctional
property
and
intrinsic
molecular
aiding
effective
diagnosis,
imaging,
successful
therapy.
However,
chemically
synthesized
nanoparticles
several
issues
related
the
cost,
toxicity
effectiveness.
this
context,
bio-inspired
(NPs)
held
edges
over
conventionally
low
easy
synthesis
toxicity.
present
review
article,
a
detailed
overview
of
has
been
provided.
This
includes
examples
liposomes,
lipid
nanoparticles,
protein
inorganic
viral
nanoparticles.
Finally,
challenges
future
scopes
these
NPs
therapy
diagnostics
are
highlighted.
Molecules,
Journal Year:
2020,
Volume and Issue:
25(20), P. 4613 - 4613
Published: Oct. 10, 2020
Polyphenols
are
micronutrients
that
widely
present
in
human
daily
diets.
Numerous
studies
have
demonstrated
their
potential
as
antioxidants
and
anti-inflammatory
agents,
for
cancer
prevention,
heart
protection
the
treatment
of
neurodegenerative
diseases.
However,
due
to
vulnerability
environmental
conditions
low
bioavailability,
application
food
medical
fields
is
greatly
limited.
Nanoformulations,
excellent
drug
delivery
systems,
can
overcome
these
limitations
maximize
pharmacological
effects
polyphenols.
In
this
review,
we
summarize
biological
activities
polyphenols,
together
with
systems
delivery,
including
phospholipid
complexes,
lipid-based
nanoparticles,
protein-based
niosomes,
polymers,
micelles,
emulsions
metal
nanoparticles.
The
polyphenol
nanoparticles
medicine
also
discussed.
Although
loading
into
solves
main
limitation
polyphenolic
compounds,
there
some
concerns
about
toxicological
safety
after
entry
body.
It
therefore
necessary
conduct
toxicity
residue
analysis
on
carrier.
RSC Advances,
Journal Year:
2021,
Volume and Issue:
11(40), P. 24722 - 24746
Published: Jan. 1, 2021
Bioinspired
metallic
nanoparticles
(BMN)
have
revolutionized
the
biomedical
domain
and
are
still
developing
rapidly.
Hence,
this
review
on
BMN
elaborates
properties,
biosynthesis,
applications,
its
role
in
combating
SARS-CoV-2.
Nanomaterials,
Journal Year:
2022,
Volume and Issue:
12(7), P. 1102 - 1102
Published: March 27, 2022
Nanoparticles
are
currently
used
for
cancer
theranostics
in
the
clinical
field.
Among
nanoparticles,
gold
nanoparticles
(AuNPs)
attract
much
attention
due
to
their
usability
and
high
performance
imaging
techniques.
The
wide
availability
of
biological
precursors
plant-based
synthesized
AuNPs
allows
development
large-scale
production
a
greener
manner.
Conventional
therapies,
such
as
surgery
chemotherapy,
have
significant
limitations
frequently
fail
produce
satisfying
results.
prolonged
circulation
time,
allow
easy
modification
with
ligands
detected
via
cell
surface
receptors,
increase
uptake
through
receptor-mediated
endocytosis.
To
exploit
these
unique
features,
studies
been
carried
out
on
use
contrast
agents
X-ray-based
techniques
(i.e.,
computed
tomography).
As
nanocarriers,
by
nontoxic
biocompatible
plants
deliver
therapeutic
biomolecules
could
be
stride
forward
effective
treatment
various
cancers.
Fluorescent-plant-based
markers,
including
AuNPs,
fabricated
using
Medicago
sativa,
Olax
Scandens,
H.
ambavilla,
lanceolatum,
detecting
Moreover,
green
extracts
applied
different
types
solid
tumors.
However,
cytotoxicity
primarily
depends
size,
reactivity,
area.
In
this
review,
benefits
materials
therapy
firstly
explained.
Then,
considering
valuable
position
medicine,
application
detection
is
highlighted
an
emphasis
faced
NPs
drug
delivery
platforms.
Journal of Functional Biomaterials,
Journal Year:
2021,
Volume and Issue:
12(4), P. 70 - 70
Published: Dec. 3, 2021
Gold
nanoparticles
(AuNPs)
are
extremely
promising
objects
for
solving
a
wide
range
of
biomedical
problems.
The
gold
production
by
biological
method
(“green
synthesis”)
is
eco-friendly
and
allows
minimization
the
amount
harmful
chemical
toxic
byproducts.
This
review
devoted
to
AuNPs
biosynthesis
peculiarities
using
various
living
organisms
(bacteria,
fungi,
algae,
plants).
participation
biomolecules
in
synthesis
influence
size,
shapes,
capping
agents
on
functionalities
described.
proposed
action
mechanisms
target
cells
highlighted.
activities
“green”
(antimicrobial,
anticancer,
antiviral,
etc.)
possibilities
their
further
application
also
discussed.
Frontiers in Oncology,
Journal Year:
2022,
Volume and Issue:
12
Published: April 22, 2022
Colorectal
cancer
(CRC)
is
one
of
the
most
common
and
reoccurring
diseases,
as
well
world's
second
largest
cause
mortality.
Despite
existing
preventative,
diagnostic,
treatment
methods,
such
chemotherapy,
number
instances
rises
year
after
year.
As
a
result,
new
effective
medications
targeting
specific
checkpoints
should
be
developed
to
combat
CRC.
Natural
compounds,
curcumin,
have
shown
significant
anti-colorectal
characteristics
among
that
can
used
treat
These
chemicals
are
phenolic
compounds
belong
curcuminoids
category.
Curcumin
exerts
its
anti-proliferative
properties
against
CRC
cell
lines
in
vitro
vivo
via
variety
mechanisms,
including
suppression
intrinsic
extrinsic
apoptotic
signaling
pathways,
stoppage
cycle,
activation
autophagy.
also
has
anti-angiogenesis
properties.
Thus,
this
review
aimed
at
emphasizing
biological
effect
mode
action
curcumin
on
Furthermore,
critical
role
these
substances
chemoprevention
was
emphasized.
