Imaging Neuroscience,
Год журнала:
2024,
Номер
2, С. 1 - 15
Опубликована: Апрель 15, 2024
Abstract
During
states
of
anxiety,
fundamental
threat
circuitry
in
the
brain
can
increase
heart
rate
via
alterations
autonomic
balance
(increased
sympathetic
activity
and
parasympathetic
withdrawal)
may
serve
to
promote
interoceptive
integration
awareness
cardiac
signals.
Moreover,
evidence
indicates
pathological
anxiety
could
be
associated
with
increased
communication
between
heart.
Yet,
this
phenomenon
remains
not
well
understood.
For
instance,
studies
area
have
been
conducted
within
confines
tightly
controlled
experimental
paradigms.
Whether
impacts
brain-heart
outside
such
settings,
relatively
more
naturalistic
contexts,
is
less
clear.
Here,
we
used
a
suspenseful
movie
fMRI
paradigm
study
induced
(n
=
29
healthy
volunteers;
Caltech
Conte
dataset;
Kliemann
et
al.,
2022).
We
predicted
that
responses
across
an
anxiety-relevant
“defensive
response
network”
(amygdala,
hypothalamus,
periaqueductal
gray,
bed
nucleus
stria
terminalis,
dorsomedial
prefrontal
cortex,
ventromedial
subgenual
anterior
cingulate,
insula;
Abend
2022)
would
show
coherence
as
participants
watched
clip
compared
non-suspenseful
clip.
Counter
our
predictions,
found
decreased
during
namely
amygdala-prefrontal
circuitry.
suggest
these
underpinned
by
withdrawal
and/or
movie-watching.
Neuroscience & Biobehavioral Reviews,
Год журнала:
2024,
Номер
157, С. 105542 - 105542
Опубликована: Янв. 11, 2024
Coordinated
interactions
between
the
central
and
autonomic
nervous
systems
are
crucial
for
survival
due
to
inherent
propensity
human
behavior
make
errors.
In
our
ever-changing
environment,
when
individuals
mistakes,
these
errors
can
have
life-threatening
consequences.
response
errors,
specific
reactions
occur
in
both
brain
activity
heart
rate
detect
correct
Specifically,
there
two
brain-related
indicators
of
error
detection
awareness
known
as
error-related
negativity
positivity.
Conversely,
cardiac
deceleration
denotes
a
momentary
slowing
following
an
error,
signaling
response.
However,
what
is
connection
during
processing?
this
review,
we
discuss
functional
neuroanatomical
connections
markers
processing,
exploring
experimental
conditions
which
they
covary.
Given
current
limitations
available
data,
future
research
will
continue
investigate
neurobiological
factors
governing
brain-heart
interaction,
aiming
utilize
them
combined
assessing
cognitive
control
healthy
pathological
conditions.
Proceedings of the National Academy of Sciences,
Год журнала:
2024,
Номер
121(5)
Опубликована: Янв. 25, 2024
Emotions,
bodily
sensations
and
movement
are
integral
parts
of
musical
experiences.
Yet,
it
remains
unknown
i)
whether
emotional
connotations
structural
features
music
elicit
discrete
ii)
these
culturally
consistent.
We
addressed
questions
in
a
cross-cultural
study
with
Western
(European
North
American,
n
=
903)
East
Asian
(Chinese,
1035).
precented
participants
silhouettes
human
bodies
asked
them
to
indicate
the
regions
whose
activity
they
felt
changing
while
listening
pieces
varying
acoustic
qualities.
The
resulting
sensation
maps
(BSMs)
varied
as
function
qualities
songs,
particularly
limb,
chest,
head
regions.
Music-induced
emotions
corresponding
BSMs
were
replicable
across
subjects.
clustered
similarly
cultures,
cluster
structures
similar
for
self-reports
experience.
consistently
associated
emotion
ratings
music-induced
cultures.
These
results
highlight
importance
subjective
experience
demonstrate
consistent
associations
between
features,
emotions,
distant
Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Фев. 20, 2024
Abstract
Uncertainty
about
potential
future
threats
and
the
associated
anxious
anticipation
represents
a
key
feature
of
anxiety.
However,
neural
systems
that
underlie
subjective
experience
threat
under
uncertainty
remain
unclear.
Combining
an
uncertainty-variation
paradigm
allows
precise
modulation
level
momentary
arousal
during
functional
magnetic
resonance
imaging
(fMRI)
with
multivariate
predictive
modeling,
we
train
brain
model
accurately
predicts
intensity
test
it
across
9
samples
(total
n
=
572,
both
gender).
Using
publicly
available
datasets,
demonstrate
whole-brain
signature
specifically
is
not
sensitive
in
predicting
pain,
general
or
unspecific
emotional
autonomic
arousal.
The
also
functionally
spatially
distinguishable
from
representations
fear
negative
affect.
We
develop
sensitive,
generalizable,
specific
neuroimaging
marker
for
uncertain
can
facilitate
development.
The Journal of Physiology,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 8, 2025
The
intricate
role
of
the
autonomic
nervous
system
(ANS)
in
regulating
cardiac
physiology
has
long
been
recognized.
Aberrant
function
ANS
is
central
to
pathophysiology
cardiovascular
diseases.
It
stands
reason,
therefore,
that
neuroscience-based
therapeutics
hold
great
promise
treatment
diseases
humans.
A
decade
after
inaugural
edition,
this
White
Paper
reviews
current
state
understanding
human
neuroanatomy,
neurophysiology
and
specific
disease
conditions,
testing,
risk
stratification,
neuromodulatory
strategies
mitigate
progression
Imaging Neuroscience,
Год журнала:
2024,
Номер
2, С. 1 - 24
Опубликована: Апрель 1, 2024
Abstract
It
has
been
shown
that
cessation
of
intensive
sensory
stimulation
is
associated
with
a
transient
increase
in
functional
inhibition
the
cortical
areas.
However,
electrophysiological
correlates
this
post-stimulus
human
brain
have
not
thoroughly
investigated.
To
investigate
inhibition,
we
analyzed
magnetoencephalogram
(MEG)
recorded
at
rest
and
after
visual
varying
intensity
(high-contrast
gratings
drifting
slow,
medium,
or
high
rate)
25
healthy
women
aged
18–40
years.
We
condition-
intensity-related
changes
MEG
parameters
sensitive
to
inhibition:
periodic
alpha-beta
power,
peak
alpha
frequency
(PAF),
1/f
aperiodic
slope.
also
investigated
association
these
sensitivity
avoidance
assessed
by
questionnaire.
evaluate
influence
hormonal
status
on
studied
parameters,
participants
were
examined
twice,
during
follicular
luteal
phases
menstrual
cycle
(MC).
Regardless
MC
phase,
increasing
drift
rate
resulted
proportional
posterior
PAF,
negative
shift
(1/f)
slope
power
spectrum
high-frequency
range.
Compared
rest,
periods
characterized
higher
more
areas,
widespread
beta
power.
While
drift-rate-dependent
modulations
correlated,
PAF
did
correlate
either
them.
A
greater
intensity-dependent
predicted
subjective
sensitivity/avoidance,
suggesting
stronger
regulatory
top-down
modulation
cortex
individuals
heightened
sensitivity.
Our
results
show
several
concordantly
indicate
enhancement
preceding
stimulation.
may
share
some
common
mechanisms,
reflect
distinct
aspect
inhibitory
regulation.
inform
potential
inhibition-based
biomarkers
for
clinical
translational
research.
