Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Alzheimer’s disease

Pathology - Research and Practice, Год журнала: 2023, Номер 253, С. 155007 - 155007

Опубликована: Дек. 4, 2023

Язык: Английский

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The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance

Pathology - Research and Practice, Год журнала: 2023, Номер 251, С. 154880 - 154880

Опубликована: Окт. 11, 2023

Язык: Английский

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miRNAs as modulators of neuroinflammation and excitotoxicity: Implications for stroke therapeutics

Pathology - Research and Practice, Год журнала: 2024, Номер 253, С. 155093 - 155093

Опубликована: Янв. 1, 2024

Язык: Английский

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Deciphering signaling pathway interplay via miRNAs in malignant pleural mesothelioma

Pathology - Research and Practice, Год журнала: 2023, Номер 252, С. 154947 - 154947

Опубликована: Ноя. 13, 2023

Язык: Английский

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Decoding the role of miRNAs in oral cancer pathogenesis: A focus on signaling pathways

Pathology - Research and Practice, Год журнала: 2023, Номер 252, С. 154949 - 154949

Опубликована: Ноя. 18, 2023

Язык: Английский

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The emerging role of miRNAs in myocardial infarction: From molecular signatures to therapeutic targets

Pathology - Research and Practice, Год журнала: 2024, Номер 253, С. 155087 - 155087

Опубликована: Янв. 1, 2024

Язык: Английский

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Evaluation of the Antioxidant and Anti-Cancer Potential of Microwave-Assisted Opuntia humifusa (Korean Cheonnyencho) Aqueous Extract

Current Issues in Molecular Biology, Год журнала: 2025, Номер 47(2), С. 88 - 88

Опубликована: Янв. 31, 2025

O. humifusa (Korean Cheonnyencho), a prickly pear cactus species, has garnered increased attention owing to its rich phytochemical composition and potential health benefits. In this study, the antioxidant anti-cancer activities of microwave-assisted aqueous extract derived from were investigated, content was characterized. High-performance liquid chromatography (HPLC) used identify various bioactive compounds, including polyphenols, flavonoids, other antioxidants known for their health-promoting properties. Furthermore, individual compounds in flavonoids separated using HPLC fractionation technique. The evaluated 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity. results demonstrated significant activity extract, as evidenced by ability scavenge free radicals effectively reduce oxidized molecules. experiments involved treating colon cancer cells with varying concentrations (25 125 mg/mL) over 24-h period, resulting remarkable dose-dependent inhibition cell growth. Notably, inhibitory effect absent HDFa cells, highlighting selectivity targeting cells.

Язык: Английский

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Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Parkinson’s disease

Pathology - Research and Practice, Год журнала: 2023, Номер 253, С. 155023 - 155023

Опубликована: Дек. 10, 2023

Язык: Английский

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The potential relevance of long non-coding RNAs in colorectal cancer pathogenesis and treatment: A review focus on signaling pathways

Pathology - Research and Practice, Год журнала: 2023, Номер 253, С. 155044 - 155044

Опубликована: Дек. 20, 2023

Язык: Английский

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MicroRNA-98: the multifaceted regulator in human cancer progression and therapy

Cancer Cell International, Год журнала: 2024, Номер 24(1)

Опубликована: Июнь 13, 2024

MicroRNA-98 (miR-98) stands as an important molecule in the intricate landscape of oncology. As a subset microRNAs, these small non-coding RNAs have accompanied new era cancer research, underpinning their significant roles tumorigenesis, metastasis, and therapeutic interventions. This review provides comprehensive insight into biogenesis, molecular properties, physiological undertakings miR-98, highlighting its double-edged role progression-acting both tumor promoter suppressor. Intriguingly, miR-98 has profound implications for various aspects progression, modulating key cellular functions, including proliferation, apoptosis, cell cycle. Given expression patterns, potential diagnostic prognostic biomarker, especially liquid biopsies tissues, is explored, emphasizing hurdles translating findings clinically. The concludes by evaluating avenues to modulate expression, addressing challenges therapy resistance, assessing efficacy In conclusion, while miR-98's involvement showcases promising avenues, future research should pivot towards understanding tumor-stroma interactions, immune modulation, metabolic regulation, thereby unlocking novel strategies management.

Язык: Английский

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