Frontiers in Neurology,
Год журнала:
2021,
Номер
12
Опубликована: Янв. 27, 2021
At
its
best,
human-centric
lighting
considers
the
visual
and
non-visual
effects
of
light
in
support
positive
human
outcomes.
worst,
it
is
a
marketing
phrase
used
to
healthwash
products
or
design
solutions.
There
no
doubt
that
environmental
contributes
health,
but
how
might
one
practice
given
both
credible
potential
implausible
hype?
Marketing
literature
filled
with
promises.
Technical
societies
have
summarized
science
not
yet
offered
guidance.
Meanwhile,
designers
are
middle,
attempting
distinguish
knowledge
from
which
dubious
make
decisions
affect
people
directly.
This
article
intended
to:
(1)
empower
reader
fundamental
understandings
ways
affects
health;
(2)
provide
process
for
can
dovetail
decision-making
already
part
designer's
workflow.
PLoS Biology,
Год журнала:
2022,
Номер
20(3), С. e3001571 - e3001571
Опубликована: Март 17, 2022
Ocular
light
exposure
has
important
influences
on
human
health
and
well-being
through
modulation
of
circadian
rhythms
sleep,
as
well
neuroendocrine
cognitive
functions.
Prevailing
patterns
do
not
optimally
engage
these
actions
for
many
individuals,
but
advances
in
our
understanding
the
underpinning
mechanisms
emerging
lighting
technologies
now
present
opportunities
to
adjust
promote
optimal
physical
mental
performance.
A
newly
developed,
international
standard
provides
a
SI-compliant
way
quantifying
influence
intrinsically
photosensitive,
melanopsin-expressing,
retinal
neurons
that
mediate
effects.
The
report
recommendations
lighting,
based
an
expert
scientific
consensus
expressed
easily
measured
quantity
(melanopic
equivalent
daylight
illuminance
(melaponic
EDI))
defined
within
this
standard.
are
supported
by
detailed
analysis
sensitivity
circadian,
neuroendocrine,
alerting
responses
ocular
provide
straightforward
framework
inform
design
practice.
Annual Review of Nutrition,
Год журнала:
2019,
Номер
39(1), С. 291 - 315
Опубликована: Июнь 10, 2019
Molecular
clocks
are
present
in
almost
every
cell
to
anticipate
daily
recurring
and
predictable
changes,
such
as
rhythmic
nutrient
availability,
adapt
cellular
functions
accordingly.
At
the
same
time,
nutrient-sensing
pathways
can
respond
acute
imbalance
modulate
orient
metabolism
so
cells
optimally
a
declining
or
increasing
availability
of
nutrients.
Organismal
circadian
rhythms
coordinated
by
behavioral
activity-rest
feeding-fasting
cycles
temporally
orchestrate
sequence
physiological
processes
optimize
metabolism.
Basic
research
has
largely
focused
on
functioning
self-sustaining
molecular
oscillator,
while
nutrition
science
yielded
insights
into
responses
caloric
deprivation
specific
macronutrients.
Integration
these
two
fields
actionable
new
concepts
timing
food
intake
led
emerging
practice
time-restricted
eating.
In
this
paradigm,
is
restricted
consistent
window
8-12
h.
This
paradigm
pervasive
benefits
multiple
organ
systems.
European Journal of Neuroscience,
Год журнала:
2018,
Номер
51(1), С. 531 - 550
Опубликована: Ноя. 7, 2018
The
circadian
system
regulates
physiology
and
behavior.
Acute
challenges
to
the
system,
such
as
those
experienced
when
traveling
across
time
zones,
will
eventually
result
in
re-synchronization
local
environmental
cues,
but
this
is
oftentimes
accompanied
by
adverse
short-term
consequences.
When
are
chronically,
adaptation
may
not
be
achieved,
for
example
case
of
rotating
night
shift
workers.
transient
chronic
disturbance
most
frequently
referred
"circadian
disruption",
many
other
terms
have
been
proposed
used
refer
similar
situations.
It
now
beyond
doubt
that
contributes
health
disease,
emphasizing
need
clear
terminology
describing
their
goal
review
provide
an
overview
describe
disruption
discuss
quantifications
experimental
observational
settings
with
a
focus
on
human
research,
highlight
limitations
currently
available
tools.
For
research
advance
translational
science,
clear,
operationalizable,
scalable
key,
they
enable
improved
assessment
reproducibility
results,
ideally
ranging
from
mechanistic
settings,
including
animal
large-scale
randomized
clinical
trials.
