A systematic review of the effects of nanoplastics on fish DOI Creative Commons
Asok K. Dasmahapatra,

Joydeep Chatterjee,

Paul B. Tchounwou

и другие.

Frontiers in Toxicology, Год журнала: 2025, Номер 7

Опубликована: Май 30, 2025

The global concern about plastics has been amplified due to their widespread contamination in the environment and ability cross biological barriers living organisms. However, our understanding of bioaccumulation, toxicity, interaction with other environmental pollutants remains limited. Plastics are classified into three categories: macro-(MAP > 5 mm), micro-(MIP, <5 nanoplastics (NAP≤ 100 nm). Among these, NAPs have superior sorption capacity, a large surface area, greater release co-contaminants tissues, resulting more complex harmful effects compared MAPs MIPs. To assess toxic NAPs, particularly genotoxicity fish, we carried out bibliographic search PubMed using terms “nanoplastics” “fish,” which yielded 233 articles. These studies focused on various polymers including polyamide (PA), polycarbonate (PC), polyethylene (PE), terephthalate (PET), polymethylmethacrylate (PMMA), polypropylene (PPP), polystyrene (PS), polyvinyl chloride (PVC). We further refined by fish species such as common carp, fathead minnows, medaka, tilapia, trout, zebrafish selected 114 articles for review. This article provides comprehensive overview current state knowledge fishes, emphasizing metals, polycyclic aromatic hydrocarbons, pharmaceuticals, pesticides, antibiotics, plastic additives, endocrine disruptors found aquatic environments. Our findings indicate that among species, (∼68%) is most frequently studied, while PS (∼89%) commonly encountered NAP ecosystems. Despite substantial experimental variability, systematic review highlights accumulate tissues skin, muscle, gill, gut, liver, heart, gonads, brain across all developmental stages, from embryos adults. exposure leads significant adverse increased oxidative stress, decreased locomotor foraging activities, altered growth, immunity, lipid metabolism, induced neurotoxicity. Furthermore, modulates estrogen–androgen–thyroid–steroidogenesis (EATS) pathways shows potential intergenerational effects. Although USEPA EU aware impacts pollution, prolonged persistence continues pose risk both life human health.

Язык: Английский

Effects of microplastics and nanoplastics in shrimp: Mechanisms of plastic particle and contaminant distribution and subsequent effects after uptake DOI Creative Commons
Anil Timilsina, Kaushik Adhikari, Amit Kumar Yadav

и другие.

The Science of The Total Environment, Год журнала: 2023, Номер 894, С. 164999 - 164999

Опубликована: Июнь 20, 2023

To date, previous studies have reported the adverse effects of microplastics (MPs) and nanoplastics (NPs) on both freshwater marine organisms. However, information MPs' NPs' shrimp species is scarce. In addition, factors influencing distribution these particles in aquatic systems been explained, yet mechanisms behind MPs NPs consumption, specifically to crustaceans shrimp, not elucidated detail. The as well plastic-carried contaminants pathogens are critical production subsequent human consumption. Recent findings required review discuss open up new avenues for emerging Shrimp crustacean research sustainability. This summarizes fate along with identifies potential risks health. transport influenced by their plastic properties, hydrodynamics, water properties. Additionally, a surface (plastisphere) regulated contaminant Pathogens thriving surfaces adsorbed can reach organisms directly or indirectly after release an environment. be absorbed through gills mouth accumulate internal organs. Innate immunity degree survival rate, tissue damage, alteration gut microbiota, increased oxidative stress caused accumulation. still sufficient understand how from various parts body plastics inside body.

Язык: Английский

Процитировано

50
The invisible Threat: Assessing the reproductive and transgenerational impacts of micro- and nanoplastics on fish DOI Creative Commons

Jia Yi,

Yilei Ma,

Jing Ruan

и другие.

Environment International, Год журнала: 2024, Номер 183, С. 108432 - 108432

Опубликована: Янв. 1, 2024

Micro- and nanoplastics (MNPs), emerging as pervasive environmental pollutants, present multifaceted threats to diverse ecosystems. This review critically examines the ability of MNPs traverse biological barriers in fish, leading their accumulation gonadal tissues subsequent reproductive toxicity. A focal concern is potential transgenerational harm, where offspring not directly exposed exhibit toxic effects. Characterized by extensive specific surface areas marked hydrophobicity, readily adsorb concentrate other contaminants, potentially intensifying comprehensive analysis aims provide profound insights into repercussions on fish health progeny, highlighting intricate interplay between pollutants. We delve mechanisms MNPs-induced toxicity, including histopathologic alterations, oxidative stress, disruptions hypothalamic-pituitary-gonadal axis. The also underscores urgency for future research explore size-specific dynamics long-term implications chronic exposure. Understanding these aspects crucial assessing ecological risks posed formulating strategies safeguard aquatic life.

Язык: Английский

Процитировано

22
Biological uptake, distribution and toxicity of micro(nano)plastics in the aquatic biota: A special emphasis on size-dependent impacts DOI Open Access
Wanjing Liu,

Hongping Liao,

Maochun Wei

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 170, С. 117477 - 117477

Опубликована: Дек. 6, 2023

Язык: Английский

Процитировано

41
Toxicity of microplastics and nanoplastics: invisible killers of female fertility and offspring health DOI Creative Commons

Yuli Geng,

Zhuo Liu,

Runan Hu

и другие.

Frontiers in Physiology, Год журнала: 2023, Номер 14

Опубликована: Авг. 28, 2023

Microplastics (MPs) and nanoplastics (NPs) are emergent pollutants, which have sparked widespread concern. They can infiltrate the body via ingestion, inhalation, cutaneous contact. As such, there is a general worry that MPs/NPs may an impact on human health in addition to environmental issues they engender. The threat of liver, gastrointestinal system, inflammatory levels been thoroughly documented previous research. With detection fetal compartment prevalence infertility, increasing number studies put emphasis their reproductive toxicity female. Moreover, potential interact with other contaminants, thus enhancing or diminishing combined toxicity. This review summarizes deleterious effects co-exposure pollutants female throughout reproduction period various species, spanning from failure cross-generational developmental disorders progenies. Although these impacts not be directly extrapolated humans, do provide framework for evaluating mechanisms underlying MPs/NPs.

Язык: Английский

Процитировано

29
Combined Effects of Polystyrene Nanosphere and Homosolate Exposures on Estrogenic End Points in MCF-7 Cells and Zebrafish DOI Creative Commons
Rongyi Ye, Zhiming Li,

Hongyi Xian

и другие.

Environmental Health Perspectives, Год журнала: 2024, Номер 132(2)

Опубликована: Фев. 1, 2024

Micro- and nanoplastics (MNPs) homosalate (HMS) are ubiquitous emerging environmental contaminants detected in human samples. Despite the well-established endocrine-disrupting effects (EDEs) of HMS, interaction between MNPs HMS its impact on HMS-induced EDEs remain unclear.

Язык: Английский

Процитировано

16
Exposure to polystyrene nanoplastics induces abnormal activation of innate immunity via the cGAS-STING pathway DOI Creative Commons
Lihui Xuan, Yin Wang,

Can Qu

и другие.

Ecotoxicology and Environmental Safety, Год журнала: 2024, Номер 275, С. 116255 - 116255

Опубликована: Март 28, 2024

Endogenous immune defenses provide an intrinsic barrier against external entity invasion. Microplastics in the environment, especially those at nanoscale (nanoplastics or NPs), may pose latent health risks through direct exposure. While links between nanoplastics and inflammatory processes have been established, detailed insights into how they perturb innate mechanisms remain uncharted. Employing murine macrophage (RAW264.7) cellular models subjected to polystyrene (PS-NPs), our investigative approach encompassed array of techniques: Cell Counting Kit-8 assays, flow cytometric analysis, acridine orange/ethidium bromide (AO/EB) fluorescence staining, cell transfection, cycle scrutiny, genetic manipulation, messenger RNA expression profiling via quantitative real-time PCR, protein evaluation western blotting. The results showed that PS-NPs caused RAW264.7 apoptosis, leading arrest, activated cGAS-STING pathway. This resulted NF-κB signaling activation increased pro-inflammatory mediator expression. Importantly, PS-NPs-induced its downstream cascade were markedly diminished after silencing STING gene. Our findings highlight critical role pathway immunotoxic effects induced by PS-NPs. We outline a new mechanism whereby trigger dysregulated responses cGAS/STING

Язык: Английский

Процитировано

15
Behavioral Studies of Zebrafish Reveal a New Perspective on the Reproductive Toxicity of Micro- and Nanoplastics DOI Creative Commons
Baihui Wu,

Haiyang Yu,

Jia Yi

и другие.

Toxics, Год журнала: 2024, Номер 12(3), С. 178 - 178

Опубликована: Фев. 26, 2024

The escalating prevalence of microplastics and nanoplastics in aquatic environments is a major challenge affecting the behavior reproductive health organisms while posing potential risks to human ecosystems. This review focuses on neurobehavioral changes toxicity MNPs zebrafish their relationships. At same time, caused by were studied, synergistic effects interaction these pollutants with other environmental contaminants explored. In addition, zebrafish, as model organism, provide valuable insights into subtle but important behavior, which critical for understanding success, suggesting that behavioral can serve an early biomarker toxicity. based classical endocrine disruptor models research methods, current status was reviewed, further indicated parameters be used effective rapid tool evaluate MNPs. However, methods rapidly assessing are still area exploration. To address limitations challenges scope research, this outlines future directions aim improving our impacts work aims inform targeted policies advance public strategies growing pollution.

Язык: Английский

Процитировано

14
Gender-specific effects of polystyrene nanoplastic exposure on triclosan-induced reproductive toxicity in zebrafish (Danio rerio) DOI
Zhiming Li,

Hongyi Xian,

Rongyi Ye

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 932, С. 172876 - 172876

Опубликована: Апрель 29, 2024

Язык: Английский

Процитировано

14
Strategies for the Remediation of Micro- and Nanoplastics from Contaminated Food and Water: Advancements and Challenges DOI Creative Commons
Manikant Tripathi, Pankaj Singh,

Sukriti Pathak

и другие.

Journal of Xenobiotics, Год журнала: 2025, Номер 15(1), С. 30 - 30

Опубликована: Фев. 9, 2025

Micro- and nanoplastic (MNP) pollution is a significant concern for ecosystems worldwide. The continuous generation extensive utilization of synthetic plastics have led to the widespread contamination water food resources with MNPs. These pollutants originate from daily-use products industrial waste. Remediation such essential protect human health since these ubiquitous contaminants pose serious biological environmental hazards by contaminating chains, sources, air. Various remediation techniques, including physical, chemical, sophisticated filtration, microbial bioremediation, adsorption employing novel materials, provide encouraging avenues tackling this worldwide issue. biotechnological approaches stand out as effective, eco-friendly, sustainable solutions managing toxic pollutants. However, complexity MNP presents challenges in its management regulation. Addressing requires cross-disciplinary research efforts develop implement more efficient, sustainable, scalable techniques mitigating pollution. This review explores various sources micro- resources, their impacts, strategies—including advanced approaches—and treating alleviate effects on health.

Язык: Английский

Процитировано

2
The impact of microplastics on female reproduction and early life DOI Creative Commons
J Yang, Jorke H. Kamstra, Juliette Legler

и другие.

Animal Reproduction, Год журнала: 2023, Номер 20(2)

Опубликована: Янв. 1, 2023

Plastic pollution in our environment is one of the most important global health concerns right now. Micro- and nanoplastics (MNPs) are taken up by both humans animals, mainly via food water, can pass epithelial barriers. Indications plastics blood circulation have recently been shown farm but standardized methods to quantify exact levels MNPs which we exposed currently lacking. Potential hazards being investigated very recently, including impact that may on reproduction. However, studies mammalian reproduction scarce, a wealth data from aquatic species indicates reproductive effects MNPs. The first rodent models demonstrate reach gonads after oral exposure offspring maternal during gestational period. These arise particles themselves or presence plastic contaminants leach plastics. contamination has detected human placentas, fetal fluid meconium newborns, indicating start life. Currently there lack investigate MNP periconception embryonic period, whereas this an extremely sensitive period needs considerable attention with growing amount environment.

Язык: Английский

Процитировано

20