Environmental Science & Technology,
Год журнала:
2024,
Номер
58(42), С. 18940 - 18949
Опубликована: Окт. 9, 2024
Tire
wear
particles
(TWPs)
released
during
vehicle
driving
can
enter
water
bodies,
leading
to
leaching
of
tire
additives
(TAs)
in
aquatic
environments.
However,
the
transformation
behavior
and
related
ecological
impacts
TAs
their
products
(TPs)
remain
unclear.
In
this
study,
laboratory-based
simulation
experiments
field
investigations
were
conducted
explore
mechanisms
risks
TAs.
After
being
placed
river
for
24
h,
about
7–95%
12
investigated
TWPs
leached.
Forty-eight
TPs
from
eight
tentatively
identified
along
with
different
pathways
via
suspect
screening
by
high-resolution
mass
spectrometry.
Semiquantitative
results
indicated
that
derived
N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylene-diamine
(6PPD)
predominant
leachates,
while
aryl
hydrolysis
quinone
main
pathways.
Field
on
urban
surface
samples
16
sites
Hong
Kong
revealed
occurrence
17
1
TP,
concentrations
ranging
13.9
2230
ng/L
(median
±
standard
deviation:
226
534
ng/L).
Sixteen
six
additionally
screening.
It
is
estimated
6PPD-quinone
seven
could
pose
medium
high
risk,
N-(1,3-dimethylbutyl)-N′-phenyl-p-quinonediimine,
a
frequently
detected
was
as
persistent-bioaccumulative-toxic
substance.
Environmental Pollution,
Год журнала:
2024,
Номер
348, С. 123835 - 123835
Опубликована: Март 21, 2024
Plastic
pollution,
including
micro-
and
nanoplastics,
is
a
growing
concern.
Tyre-wear
particles
(TWPs)
are
the
second
largest
source
of
microplastics
in
ocean
following
abrasion
synthetic
fibres.
In
addition
to
themselves,
TWPs
contain
many
harmful
chemicals,
6PPD.
This
chemical
reacts
with
atmospheric
ozone
forms
toxic
compound
6PPD-quinone
(6PPDq),
which
poses
danger
aquatic
life.
There
knowledge
gap
understanding
risks
associated
combined
toxicity
nanoplastics
(NPs)
6PPDq.
The
present
study
aimed
investigate
NPs
6PPDq
on
adult
zebrafish
using
phenotypic
(behaviour,
histology)
transcriptomic
endpoints.
Zebrafish
were
exposed
four
treatments:
control
(contaminant-free),
50
μg/L
6PPDq,
3
mg/L
polystyrene
(PS)-NPs,
combination
PS-NPs.
We
did
not
observe
locomotory
dysregulation
NPs.
However,
we
found
significant
hyperlocomotion
this
effect
was
even
more
substantial
after
co-exposure
explores
molecular
mechanisms
behind
these
effects,
identifying
genes
neurotransmitters
fatty
acid
metabolism
that
dysregulated
by
co-exposure.
Transcriptomic
analysis
further
showed
both
PS-NPs
impacted
cellular
processes
sterol
biosynthesis,
cholesterol
metabolism,
muscle
tissue
development.
effects
stronger
co-exposed
zebrafish,
indicating
heightened
risk
integrity
mitochondrial
dysfunction.
These
results
highlight
significance
mixture
when
studying
chemicals
like
