Airborne Nanoplastics Exposure Inducing Irreversible Glucose Increase and Complete Hepatic Insulin Resistance DOI
Ziye Yang,

Huajiang Dong,

Yifei Gao

и другие.

Environmental Science & Technology, Год журнала: 2024, Номер unknown

Опубликована: Фев. 6, 2024

As an emerging type of pollutant, microplastics have become a global environmental problem. Approximately, fifth the burden 2 diabetes can be attributed to air particulate pollution. However, scientific knowledge remains limited about effects airborne nanoplastics (NPs) exposure on metabolic diseases. In this experiment, whole-body system was used simulate real atmospheric environment, and three concentrations combined with actual concentration were selected explore NPs Based histological analyses, studies, gene expression, metabolites, molecular signaling mice exposed observed show phenotype systemic inflammation complete insulin resistance featuring excessive drinking eating, weight loss, elevated blood glucose, decreased triglyceride levels. After exposure, intolerant glucose tolerant insulin. addition, could result in long-term irreversible hyperglycemia. Together, research findings provide strong basis for understanding hazards nanopollution disorders.

Язык: Английский

Raman Microspectroscopy evidence of microplastics in human semen DOI Creative Commons
Luigi Montano, Elisabetta Giorgini, Valentina Notarstefano

и другие.

The Science of The Total Environment, Год журнала: 2023, Номер 901, С. 165922 - 165922

Опубликована: Июль 31, 2023

The presence of microplastics (MPs) in human fluids and organs is a great concern, since, as highlighted by recent studies on animal models, they could cause alterations several physiological functions, including reproduction. In this study, semen samples collected from men living polluted area the Campania Region (Southern Italy), were analyzed to assess MPs. N. 16 pigmented microplastic fragments (ranging 2 6 μm size) with spheric or irregular shapes found six out ten samples. All detected MPs characterized terms morphology (size, colour, shape) chemical composition Raman Microspectroscopy. Chemical showed polypropylene (PP), polyethylene (PE), terephthalate (PET), polystyrene (PS), polyvinylchloride (PVC), polycarbonate (PC), polyoxymethylene (POM) acrylic, suggesting ingestion and/or inhalation route exposure environmental work, we propose for first time mechanism which pass into most likely through epididymis seminal vesicles, are susceptible inflammation.

Язык: Английский

Процитировано

108

From oceans to dinner plates: The impact of microplastics on human health DOI Creative Commons
Ebuka Chizitere Emenike, Chika J. Okorie,

Toluwalase Ojeyemi

и другие.

Heliyon, Год журнала: 2023, Номер 9(10), С. e20440 - e20440

Опубликована: Сен. 26, 2023

Microplastics, measuring less than 5 mm in diameter, are now found various environmental media, including soil, water, and air, have infiltrated the food chain, ultimately becoming a part of human diet. This study offers comprehensive examination intricate nexus between microplastics health, thereby contributing to existing knowledge on subject. Sources microplastics, microfibers from textiles, personal care products, wastewater treatment plants, among others, were assessed. The meticulously examined diverse routes microplastic exposure—ingestion, inhalation, dermal contact—offering insights into associated health risks. Notably, ingestion has been linked gastrointestinal disturbances, endocrine disruption, potential transmission pathogenic bacteria. Inhalation airborne emerges as critical concern, with possible implications for respiratory cardiovascular health. Dermal contact, although explored, raises prospect skin irritation allergic reactions. impacts COVID-19 pollution also highlighted. Throughout manuscript, need deeper mechanistic understanding interactions systems is emphasized, underscoring urgency further research public awareness.

Язык: Английский

Процитировано

84

Sources and identification of microplastics in soils DOI Creative Commons

Weixin Fan,

Chunsheng Qiu, Qian Qu

и другие.

Soil & Environmental Health, Год журнала: 2023, Номер 1(2), С. 100019 - 100019

Опубликована: Май 23, 2023

Large-scale production, rapid consumption, insufficient recovery and management, slow degradation lead to a large accumulation of plastic waste microplastics. Microplastics are characterized as stable, small, having specific surface area strong hydrophobicity. They carriers many hydrophobic organic pollutants, heavy metals, pathogenic bacteria drug resistance genes. Worldwide, microplastic pollution in soils has attracted much attention. The progress perspectives the separation detection soil microplastics deserve comprehensive review discussion. Here, sources distributions from use agricultural film, sludge recycling, long-term application fertilizer, runoff, sewage irrigation summarized. Physical methods such density separation, electrostatic oil extraction pressurized liquid extraction, chemical acid digestion, alkaline hydrogen peroxide Fenton reagent oxidation, enzymatic hydrolysis for reviewed. Futhermore, technologies through microscopy, spectroscopy, mass spectrometry, thermogravimetric analysis, differential scanning calorimetry, X-ray photoelectron spectroscopy nuclear magnetic resonance Finally, put forward understanding impacts on functions health, developing source control environmental remediation technology, investigating low-cost that preserve characteristics microplastics, strengthen degree automation avoid artificial operation error, establish standard isolating, extracting, identifying, quantifying soils. This serves technical reference identification builds foundation scientific assessment ecological human risks

Язык: Английский

Процитировано

62

Microplastics in human blood: Polymer types, concentrations and characterisation using μFTIR DOI Creative Commons
Sophie V. L. Leonard,

Catriona R. Liddle,

Charlotte A. Atherall

и другие.

Environment International, Год журнала: 2024, Номер 188, С. 108751 - 108751

Опубликована: Май 14, 2024

Microplastics (MPs) are an everyday part of life, and now ubiquitous in the environment. Crucially, MPs have not just been found within environment, but also human bodies, including blood. We aimed to provide novel information on range MP polymer types present, as well their size shape characteristics, whole blood from 20 healthy volunteers. Twenty-four were identified 18 out (90 %) donors quantified blood, with majority observed for first time. Using LOQ approach, five met threshold a lower mean ± SD 2466 4174 MP/L. The concentrations plastics analysed samples ranged 1.84 - 4.65 μg/mL. Polyethylene (32 %), ethylene propylene diene (14 ethylene-vinyl-acetate/alcohol (12 fragments most abundant. particles that had particle length 127.99 293.26 µm (7-3000 µm), width 57.88 88.89 (5-800 µm). predominantly categorised (88 white/clear (79 %). A variety plastic additive chemicals endocrine disrupting-classed phthalates. procedural blank comprised 7 types, distinct those mainly resin (25 polyethylene terephthalate (17 polystyrene 4.80 5.59 This study adds growing evidence taken up into body transported via bloodstream. sizes raise important questions respect presence associated hazards terms potential detrimental impacts such vascular inflammation, build major organs, changes either immune cell response, or haemostasis thrombosis.

Язык: Английский

Процитировано

53

Microplastics in the Bronchoalveolar Lavage Fluid of Chinese Children: Associations with Age, City Development, and Disease Features DOI

Chunzhao Chen,

Fang Liu,

Shuting Quan

и другие.

Environmental Science & Technology, Год журнала: 2023, Номер 57(34), С. 12594 - 12601

Опубликована: Авг. 14, 2023

This study characterized the occurrence patterns of microplastics (MPs) in bronchoalveolar lavage fluid (BALF) children with pulmonary diseases. MPs were detected 89.6% BALF samples an average 4.31 ± 2.77 items/10 mL, supporting hypothesis that inhalation is a significant pathway airborne MP exposure to pediatric lungs. Inhaled predominantly composed 10 polymer types [e.g., polypropylene (41.9%), polyethylene (19.4%), and polyester (13.6%)], majority being smaller than 20 μm. levels exhibited negative correlation children's age, probably owing preferential crawling tumbling actions indoor environments underdeveloped immune systems young children. Participants living urban areas suffered from higher exposure, likely due environmental levels, compared suburban/rural residents (P < 0.05). Although no differences found between lungs community-acquired pneumonia (CAP) asthma > 0.05), severe CAP group displayed significantly contamination nonsevere indicating some yet undiscovered relationship(s) inhaled diseases may exist.

Язык: Английский

Процитировано

49

Microplastics in construction and built environment DOI Creative Commons
Lapyote Prasittisopin, Wahid Ferdous, Viroon Kamchoom‬

и другие.

Developments in the Built Environment, Год журнала: 2023, Номер 15, С. 100188 - 100188

Опубликована: Июнь 23, 2023

Plastics have been extensively used in the building and construction industries for decades. However, more plastics are utilised, microplastics released. This review analysis article summarises organises knowledge from 211 current related publications published 2014–2022. The explain kinds of employed built environment. Fabrics or textiles, fibres cementitious systems, paints, tyres roads discussed. entry points into human body reviewed next, followed by management recycled wastes. important research gaps possible solutions include using high-strength concretes surface-hardening agents is suggested to encapsulate inside matrix; DPSIR model can be holistically adopted each composite; innovative bio-chemical technology like self-healing concrete bio-degradable a viable choice; social science, law urban planning support awareness comprehension.

Язык: Английский

Процитировано

46

Neurotoxicities induced by micro/nanoplastics: A review focusing on the risks of neurological diseases DOI
Shuang Liu,

Yinling He,

Yin Jia

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 469, С. 134054 - 134054

Опубликована: Март 15, 2024

Язык: Английский

Процитировано

37

Sources, environmental fate, and impacts of microplastic contamination in agricultural soils: A comprehensive review DOI
Van-Hiep Hoang, Minh‐Ky Nguyen, Tuan‐Dung Hoang

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 950, С. 175276 - 175276

Опубликована: Авг. 3, 2024

Язык: Английский

Процитировано

37

Analysis of aged microplastics: a review DOI Creative Commons

Yanqi Shi,

Linping Shi,

Hexinyue Huang

и другие.

Environmental Chemistry Letters, Год журнала: 2024, Номер 22(4), С. 1861 - 1888

Опубликована: Апрель 4, 2024

Abstract Microplastics are emerging contaminants that undergo progressive aging under environmental conditions such as sunlight irradiation, mechanical forces, temperature variations, and the presence of biological organisms. Since modifies microplastic properties, their own toxicity trapped pollutants, advanced methods to analyze microplastics required. Here we review with focus on process, qualitative identification, quantitative characterization, chemometrics. Qualitative identification is done by techniques, thermal e.g., degradation gas chromatography–mass spectrometry, spectral infrared, Raman, fluorescent, laser techniques. Quantitative characterization microscopy mass spectrometry. Microplastic results in a series surface physical changes, biofilm formation, chemical oxidation, alternation, deterioration. Changes properties allow differentiate aged microplastics. Infrared Raman spectroscopy rapid sensitive for complex samples. Combining two techniques preferable accurate detection categorization.

Язык: Английский

Процитировано

32

Microplastic and plastic pollution: impact on respiratory disease and health DOI Creative Commons
Gwenda F. Vasse, Barbro N. Melgert

European Respiratory Review, Год журнала: 2024, Номер 33(172), С. 230226 - 230226

Опубликована: Апрель 30, 2024

Throughout their lifecycle, from production to use and upon disposal, plastics release chemicals particles known as micro- nanoplastics (MNPs) that can accumulate in the environment. MNPs have been detected different locations of human body, including our lungs. This is likely a consequence MNP exposure through air we breathe. Yet, still lack comprehensive understanding impact may on respiratory disease health. In this review, collated current body evidence implications inhalation lung health vitro , vivo occupational studies. We focused interactions between pollution specific lung-resident cells diseases. conclude it evident possess capacity affect tissue remains unclear which extent occurs ambient levels MNPs, emphasising need for more evaluation environmental everyday life.

Язык: Английский

Процитировано

30