ACS Applied Nano Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 30, 2024
The
development
of
sensitive
and
accurate
glucose
biosensors
is
significant
in
diabetic
patient
monitoring.
Here,
we
synthesize
carbon-decorated
Fe3O4
nanotubes
(Fe3O4@C
NTs)
using
a
rational
designed
template
method.
Through
catalytic
oxidation
typical
colorimetric
reaction,
the
prepared
Fe3O4@C
NTs
showed
significantly
better
peroxidase-like
oxidase-like
performances
than
other
similar
Fe3O4-based
nanomaterials.
Moreover,
optimal
pH,
temperature,
concentration
for
were
4.0,
60
°C,
40
μg/mL,
respectively.
We
additionally
investigated
steady-state
kinetics
NTs,
their
catalyzed
reactions
found
to
follow
Michaelis–Menten
model.
Based
on
activity
they
employed
label-free,
rapid,
selective,
highly
detection
H2O2
glucose,
demonstrating
potential
application
determination.
Future Medicinal Chemistry,
Год журнала:
2023,
Номер
15(23), С. 2195 - 2208
Опубликована: Ноя. 24, 2023
Background:
Medication
used
to
treat
Type
2
diabetes
by
decreasing
the
absorption
of
carbohydrates
in
intestine
consists
α-glucosidase
inhibitors.
Polyhydroquinoline
derivatives
have
attracted
interest
as
excellent
antidiabetic
agents.
Methods:
(1–17)
were
synthesized
and
tested
for
vitro
inhibitory
activity.
Results:
All
compounds
exhibited
good
activity,
having
IC50
values
from
1.23
±
0.03
73.85
0.61
μM,
compared
with
standard
drug,
acarbose.
The
binding
mechanism
these
was
deduced
docking
studies
indicated
that
a
slight
variation
orientation
compounds,
affects
their
capability.
Conclusion:
In
order
find
new
drugs,
this
study
has
discovered
prospective
lead
candidates.
ACS Applied Nano Materials,
Год журнала:
2024,
Номер
7(11), С. 12356 - 12365
Опубликована: Март 25, 2024
Low-density
lipoprotein
cholesterol
(LDL-C),
commonly
called
"bad
cholesterol",
is
crucial
to
cardiovascular
health.
Increased
LDL-C
levels
pose
a
substantial
risk
human
As
result,
there
demand
for
reliable,
affordable,
and
highly
sensitive
analytical
methods
detection.
Herein,
facile
fluorometric
aptasensor
detection
based
on
the
aptamer-enhanced
peroxidase-mimicking
activity
of
gold
nanoparticles
(AuNPs)
has
been
developed.
AuNPs
were
functionalized
with
LDL-C-specific
thiolated
aptamer
enhance
their
intrinsic
peroxidase-like
activity,
which
could
effectively
catalyze
oxidation
o-phenylenediamine
dihydrochloride
(OPD)
by
H2O2
into
yellow-fluorescent
product
2,3-diamino
phenazine
(DAP).
The
characterization
studies
confirmed
that
presence
enhances
affinity
toward
OPD
substrate,
thereby
leading
marked
increase
in
activity.
Moreover,
after
being
an
aptamer,
increased
dispersibility
substrate
achieved.
Using
as
target
analyte,
under
optimum
conditions,
linear
relationship
between
smartphone-recorded
signal
intensity
logarithm
analyte
concentration
was
observed
range
0.05–1
mg
dL–1
limit
0.0230
dL–1.
results
agree
those
obtained
clinical
laboratory
method.
This
proposed
method
readily
deployable
promising
prototype
diverse
diagnostic
applications,
particularly
biomarker
within
serum
or
plasma
samples.
It
holds
potential
yield
advantages
point-of-care
testing.
Chemosensors,
Год журнала:
2024,
Номер
12(12), С. 244 - 244
Опубликована: Ноя. 22, 2024
The
efficient
detection
of
volatile
organic
compounds
(VOCs)
is
critically
important
in
the
domains
environmental
protection,
healthcare,
and
industrial
safety.
development
metal
oxide
semiconductor
(MOS)
heterojunction
gas-sensing
materials
considered
one
most
effective
strategies
to
enhance
sensor
performance.
This
review
summarizes
discusses
types
heterojunctions
their
working
principles,
enhancement
strategies,
preparation
methodologies,
applications
acetone
ethanol
detection.
To
address
constraints
pertaining
low
sensitivity,
sluggish
response/recovery
times,
elevated
operating
temperatures
that
are
inherent
VOC
sensors,
several
improvement
methods
proposed,
including
doping
with
metals
like
Ag
Pd,
incorporating
additives
such
as
MXene
polyoxometalates,
optimizing
morphologies
through
a
fine
design,
self-doping
via
oxygen
vacancies.
Furthermore,
this
work
provides
insights
into
challenges
faced
by
MOSs
heterojunction-based
gas
sensors
outlines
future
research
directions
field.
will
contribute
foundational
theories
overcome
existing
bottlenecks
MOS
technology
while
promoting
its
large-scale
application
disease
screening
or
agricultural
food
quality
assessments.
International Journal of Electrochemical Science,
Год журнала:
2023,
Номер
18(12), С. 100363 - 100363
Опубликована: Сен. 28, 2023
The
goal
of
this
study
was
to
develop
a
TiO2
and
BiVO4
heterostructure
nano-photocatalyst
for
the
photocatalytic
treatment
hydrolyzed
polyacrylamide
(HPAM)
in
oilfields
utilizing
visible
light
irradiation.
A
straightforward
coupling
technique
used
create
BiVO4/TiO2
heterojunction
photocatalysts.
Results
SEM,
EDS,
XRD
studies,
as
well
chemical
composition
identified
by
XPS,
gave
proof
that
nanocomposite
effectively
synthesized.
bandgaps
pure
BiVO4,
TiO2,
5%,
10%,
15%,
20%,
50%
nanocomposites
are
2.53
eV,
3.21
3.03
2.89
2.69
2.64
2.58
respectively.
According
optical
addition
improved
harvesting
capability,
particularly
range.
By
adding
catalyst
structure,
charge-transfer
resistance
reduces,
indicating
enhanced
interfacial
charge
transfer,
according
electrochemical
impedance
spectroscopy.
photodegradation
efficiency,
made
5%
BiVO4/TiO2,
10%
15%
all
degraded
completely
after
85,
115,
55,
35,
25,
45,
50
minutes
exposure
light,
on
effectiveness
degradation
HPAM
wastewater
from
an
oilfield
contains
polymers
showed
can
be
good
alternative.
