Enhanced electrochemiluminescence immunosensor using MIL-53(Fe) as co-reaction promoter of Ru(bpy)32+/PEI system for the detection of carcinoembryonic antigen

Sensors and Actuators B Chemical, Год журнала: 2024, Номер 407, С. 135498 - 135498

Опубликована: Фев. 15, 2024

Язык: Английский

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Recent advances in protein biomarkers based enzymatic biosensors for non-communicable diseases

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 174, С. 117683 - 117683

Опубликована: Апрель 4, 2024

Язык: Английский

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The combination of DNA nanostructures and materials for highly sensitive electrochemical detection

Bioelectrochemistry, Год журнала: 2024, Номер 157, С. 108651 - 108651

Опубликована: Янв. 24, 2024

Язык: Английский

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Aggregation-induced emission luminogen based ELISA for highly sensitive protein detection

Sensors and Actuators B Chemical, Год журнала: 2023, Номер 401, С. 134961 - 134961

Опубликована: Ноя. 10, 2023

Язык: Английский

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Gold nanorod in silver tetrahedron: Cysteamine mediated synthesis of SERS probes with embedded internal markers for AFP detection

Analytica Chimica Acta, Год журнала: 2025, Номер 1340, С. 343667 - 343667

Опубликована: Янв. 13, 2025

Язык: Английский

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Hydrogel-Embedded Platinum–Ruthenium Alloy Peroxidase Mimic as a Visual Sensor for “Signal-on” Alkaline Phosphatase Detection

ACS Applied Nano Materials, Год журнала: 2024, Номер 7(10), С. 11248 - 11257

Опубликована: Май 10, 2024

Nanozyme-assisted alkaline phosphatase (ALP) assay is a commonly used detection technique. However, this type of sensor faces several challenges, including "signal-off" model, dependence on oxidase mimics, and the need for spectrometers. In study, by optimizing stabilizers, we obtain chitosan-coated platinum–ruthenium nanoparticles (CS-Pt/Ru NPs) first time, which have superior peroxidase (POD) mimic activity. CS-Pt/Ru nanozymes can catalyze phenol oxidation in presence 4-aminoantipyrine hydrogen peroxide to produce an enhanced red color, while be obtained ALP-mediated hydrolysis. Thus, ALP activity quantified absorbance "signal-on" model. This approach demonstrates remarkably low limit (0.01 U·L–1) wide linear range (0.03–10 U·L–1). addition, combine with hydrogel form CS-Pt/Ru@Gel sensor, enables visual using smartphone. It detect as 0.1 U·L–1, 0.15–10 U·L–1. Finally, both Pt/Ru NPs Pt/Ru@Gel are successfully employed clinical blood samples. Our study develops excellent hydrogel-supported POD nanozyme system paves way

Язык: Английский

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Multi-functional nanozyme–based colorimetric, fluorescence dual-mode assay for Salmonella typhimurium detection in milk

Microchimica Acta, Год журнала: 2024, Номер 191(8)

Опубликована: Июль 15, 2024

Язык: Английский

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Dual-mode detection of α-fetoprotein using the photothermal effect and peroxidase-like activity of Au@Cu/Cu2O-rGO

Bioelectrochemistry, Год журнала: 2024, Номер 161, С. 108822 - 108822

Опубликована: Сен. 21, 2024

Язык: Английский

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Design of U-shaped peptides with long-lasting antifouling efficacy: Toward a feasible electrochemical aptasensor for robust detection in human serum

Analytica Chimica Acta, Год журнала: 2024, Номер 1318, С. 342953 - 342953

Опубликована: Июль 6, 2024

Язык: Английский

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A novel chemiluminescence sensor for alpha-fetoprotein detection based on an aptamer–luminol modified magnetic graphene oxide and copper-based MOF composite

Analytical Methods, Год журнала: 2024, Номер 16(33), С. 5723 - 5732

Опубликована: Янв. 1, 2024

Herein, an aptamer-luminol modified magnetic graphene oxide and copper-based MOF composite was prepared used to build a novel target-triggered "turn on" chemiluminescence (CL) sensor for alpha-fetoprotein (AFP) detection. Magnetic (MGO) functionalized with the complementary sequence of AFP aptamer (cDNA), then MGO-cDNA linked luminol (Apt-luminol) through base pairing effect. The (MGO-cDNA/Apt-luminol) as specific separation signal switch material. ZnONPs-Au@CuMOFs shows excellent catalytic performance catalyst luminol-H2O2 reaction. will specifically recognize bind Apt on MGO-cDNA/Apt-luminol when is present, which causes release triggers CL released encounters produces strong intensity. Therefore, method high selectivity sensitivity detecting has been established. linear range detection limit were 1.0 × 10-4-50 ng mL-1 4.2 10-5 mL-1, respectively. also exhibited good selectivity, reproducibility stability, finally in serum samples.

Язык: Английский

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