Design of Multi-Cancer VOCs Profiling Platform via a Deep Learning-Assisted Sensing Library Screening Strategy DOI

Xu Gao,

Shuoyang Ma,

Weiwei Ni

и другие.

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 10, 2025

The efficiency of sensor arrays in parallel discrimination multianalytes is fundamentally influenced by the quantity and performance elements. advent combinational design has notably accelerated generation chemical libraries, offering numerous candidates for development robust arrays. However, screening elements with superior cross-responsiveness remains challenging, impeding high-performance Herein, we propose a new deep learning-assisted, two-step strategy to identify optimal combination minimal elements, using designed volatile organic compounds (VOCs)-targeted library. 400 sensing constructed pairing 20 ionizable cationic anionic dyes library were employed various VOCs, generating plentiful color variation data. By employing feedforward neural network─random forest-recursive feature elimination (FRR) algorithm, effectively screened, resulting rapidly producing 8-element 10-element two VOC models, both achieving 100% accuracy. Furthermore, smartphone-based point-of-care testing (POCT) platform achieved cancer simulated model, image-based learning, demonstrating rationality practicality learning assembly platforms.

Язык: Английский

Navigating the landscape of optical biosensors DOI

Narlawar Sagar Shrikrishna,

Riya Sharma, Jyotirmayee Sahoo

и другие.

Chemical Engineering Journal, Год журнала: 2024, Номер 490, С. 151661 - 151661

Опубликована: Апрель 26, 2024

Язык: Английский

Процитировано

39

Multi-signal sensor array based on a fluorescent nanozyme for broad-spectrum screening of pesticides DOI
Donghui Song, Tian Tian, Le Wang

и другие.

Chemical Engineering Journal, Год журнала: 2024, Номер 482, С. 148784 - 148784

Опубликована: Янв. 17, 2024

Язык: Английский

Процитировано

31

Empowerment of AI algorithms in biochemical sensors DOI

Zhongzeng Zhou,

Tailin Xu, Xueji Zhang

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 173, С. 117613 - 117613

Опубликована: Фев. 29, 2024

Язык: Английский

Процитировано

23

Upconversion Nanoparticles Based Sensing: From Design to Point‐of‐Care Testing DOI
Jizhong Wu, Jiaxi Wu,

Wenya Wei

и другие.

Small, Год журнала: 2024, Номер 20(29)

Опубликована: Фев. 28, 2024

Rare earth-doped upconversion nanoparticles (UCNPs) have achieved a wide range of applications in the sensing field due to their unique anti-Stokes luminescence property, minimized background interference, excellent biocompatibility, and stable physicochemical properties. However, UCNPs-based platforms still face several challenges, including inherent limitations from UCNPs such as low quantum yields narrow absorption cross-sections, well constraints related energy transfer efficiencies systems. Therefore, construction high-performance is an important cornerstone for conducting relevant research. This work begins by providing brief overview mechanism UCNPs. Subsequently, it offers comprehensive summary sensors' types, design principles, optimized strategies platforms. More cost-effective promising point-of-care testing implemented based on systems are also summarized. Finally, this addresses future challenges prospects

Язык: Английский

Процитировано

17

Recent progress in microfluidic biosensors with different driving forces DOI Open Access
Yilong Liu, Haicong Shen, Xiaoping Yang

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2022, Номер 158, С. 116894 - 116894

Опубликована: Дек. 23, 2022

Язык: Английский

Процитировано

42

Food for Thought: Optical Sensor Arrays and Machine Learning for the Food and Beverage Industry DOI Creative Commons
William J. Peveler

ACS Sensors, Год журнала: 2024, Номер 9(4), С. 1656 - 1665

Опубликована: Апрель 10, 2024

Arrays of cross-reactive sensors, combined with statistical or machine learning analysis their multivariate outputs, have enabled the holistic complex samples in biomedicine, environmental science, and consumer products. Comparisons are frequently made to mammalian nose tongue this perspective examines role sensing arrays analyzing food beverages for quality, veracity, safety. I focus on optical sensor as low-cost, easy-to-measure tools use field, factory floor, even by consumer. Novel materials approaches highlighted challenges research field discussed, including sample processing/handling access significant sets train test tackle real issues industry. Finally, examine whether comparison noses tongues is helpful an industry defined human taste.

Язык: Английский

Процитировано

13

Review of Noble Metal Nanoparticle-Based Colorimetric Sensors for Food Safety Monitoring DOI
Linda Ardita Putri,

Yuliyan Dwi Prabowo,

Diva Meisya Maulina Dewi

и другие.

ACS Applied Nano Materials, Год журнала: 2024, Номер 7(17), С. 19821 - 19853

Опубликована: Авг. 16, 2024

Food safety, particularly concerning foods contaminated by toxic chemicals, has emerged as a pervasive societal concern. The prevalence of food contaminants spurred both scientific communities and industries to develop highly sensitive selective sensors for rapid precise authentication. Noble metal nanoparticles (NPs) have garnered significant attention in this regard due their exceptional properties, including high sensitivity, selectivity, stability, target binding affinity, versatility modification detect specific contaminants. Moreover, the readout such is relatively straightforward, resulting color change can be observed with naked eye. This Review aims delve into current strategies involving various noble NPs colorimetric nanosensors safety monitoring applications. It begins elucidating working principles, encompassing localized surface plasmon resonance (LSPR), enzyme-based approaches, other methodologies. Subsequently, material properties commonly utilized NPs, those gold, silver, palladium, platinum, copper, are meticulously examined, providing comprehensive overviews benefits drawbacks associated each material. Furthermore, summarizes latest use cases diverse applications, ranging from detection heavy veterinary pesticide drug residues foodborne pathogens. Lastly, it addresses remaining challenges field proposes feasible solutions, offering insights future research directions.

Язык: Английский

Процитировано

11

Metal–organic frameworks-scaffold gold nanoclusters enabled aggregation-induced enhanced fluorescent sensor array for high-throughput detection of heavy metal ions DOI
Xuemei Hu,

Zhaode Mu,

Yueyuan Li

и другие.

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113020 - 113020

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

1

Importance of artificial intelligence in evaluating climate change and food safety risk DOI Creative Commons
Shraddha Karanth, Edmund O. Benefo, Debasmita Patra

и другие.

Journal of Agriculture and Food Research, Год журнала: 2022, Номер 11, С. 100485 - 100485

Опубликована: Дек. 20, 2022

Climate change is considered primarily as a human-created phenomenon that changing the way humans live. Nowhere are impacts of climate more evident than in food ecosphere. Climate-induced changes temperature, precipitation, and rain patterns, well extreme weather events have already started impacting yield, quality, safety food. Food availability fundamental aspect ensuring security an adequate standard living. With change, there been increasing instances observed food, particularly from microbiological standpoint, its quality yield. Thus, urgent need for implementation advanced methods to predict implications (i.e., future issues) holistic perspective (overall system). Artificial Intelligence (AI) other such technologies have, over years, permeated many facets chain, spanning both farm- (or ocean-) to-fork production, testing prediction. As result, these perfectly positioned develop novel models change-induced risks. This article provides roundup latest research on use AI industry, impact social, ethical, legal limitations same. Particularly, this review stresses importance approach prediction encompassing diverse data streams help stakeholders make most informed decisions.

Язык: Английский

Процитировано

31

Aptamer functionalized gold nanoclusters as an emerging nanoprobe in biosensing, diagnostic, catalysis and bioimaging DOI
Sobia Niazi, Imran Mahmood Khan, M. Wasim Akhtar

и другие.

Talanta, Год журнала: 2023, Номер 268, С. 125270 - 125270

Опубликована: Окт. 14, 2023

Язык: Английский

Процитировано

22