Epidemiology, clinical presentation, pathophysiology, and management of long COVID: an update

Molecular Psychiatry, Год журнала: 2023, Номер 28(10), С. 4056 - 4069

Опубликована: Июль 25, 2023

Язык: Английский

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360-Degree Perspectives on Obesity

Medicina, Год журнала: 2023, Номер 59(6), С. 1119 - 1119

Опубликована: Июнь 9, 2023

Alarming statistics show that the number of people affected by excessive weight has surpassed 2 billion, representing approximately 30% world's population. The aim this review is to provide a comprehensive overview one most serious public health problems, considering obesity requires an integrative approach takes into account its complex etiology, including genetic, environmental, and lifestyle factors. Only understanding connections between many contributors synergy treatment interventions can ensure satisfactory outcomes in reducing obesity. Mechanisms such as oxidative stress, chronic inflammation, dysbiosis play crucial role pathogenesis associated complications. Compounding factors deleterious effects novel challenge posed obesogenic digital (food) environment, stigma with should not be overlooked. Preclinical research animal models been instrumental elucidating these mechanisms, translation clinical practice provided promising therapeutic options, epigenetic approaches, pharmacotherapy, bariatric surgery. However, more studies are necessary discover new compounds target key metabolic pathways, innovative ways deliver drugs, optimal combinations allopathic treatments, and, last but least, emerging biological markers for effective monitoring. With each passing day, crisis tightens grip, threatening only individual lives also burdening healthcare systems societies at large. It high time we took action confront urgent imperative address escalating global head-on.

Язык: Английский

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Suicide Crisis Syndrome: A systematic review

Suicide and Life-Threatening Behavior, Год журнала: 2024, Номер 54(3), С. 556 - 574

Опубликована: Фев. 27, 2024

The objective of this systematic review is to describe the scientific evidence for Suicide Crisis Syndrome (SCS), a presuicidal cognitive and affective state consisting five symptomatic dimensions: entrapment, disturbance, loss control, hyperarousal, social withdrawal. aim article summarize emerging literature on SCS assess extent which uniform syndrome can be assumed.

Язык: Английский

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Automatic diagnosis of mental illness using optimized dynamically stabilized recurrent neural network

Biomedical Signal Processing and Control, Год журнала: 2024, Номер 95, С. 106321 - 106321

Опубликована: Апрель 25, 2024

Язык: Английский

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Perceived work stressors and the transition to burnout among nurses in response to the pandemic: implications for healthcare organizations

Scandinavian Journal of Work Environment & Health, Год журнала: 2024, Номер 50(3), С. 158 - 167

Опубликована: Март 13, 2024

OBJECTIVES: This study aimed to assess the associations of pre-pandemic perceived work stressors and satisfaction among nurses, including nurse assistants, with burnout profiles their transitions in response pandemic. METHODS: Three hundred thirty-seven nurses working an Italian University hospital participated a longitudinal survey August 2019 investigating (assessed using HSE Indicator Tool), (Work Satisfaction Scale), (Maslach Burnout Inventory), second December 2020 assessing burnout. Using latent transition analysis, we identified then estimated between on transitions. RESULTS: We three profiles, namely engaged (67%), ineffective (15%), (18%); pandemic (37%), exhausted (51%), severe (12%). The profile consisted 70% classified before Overall, were associated both profiles. Among not prior COVID-19, hostile relationships increased [odds ratio (OR) 1.19, 95% confidence interval (CI) 1.05–1.34] decreased (OR 0.82, CI 0.68–0.98) probability exhausted. Moreover, 0.54, 0.32–0.91) participation organization 0.69, 0.51–0.93) protected from transitioning association peer support needs further investigation. CONCLUSIONS: Pre-pandemic To enhance preparedness for future crises, healthcare managers should carefully tackle work-related constraints affecting nurses.

Язык: Английский

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False Positives for Criterion A Trauma Events and Posttraumatic Stress Disorder Symptoms with Questionnaires Are Common in Children and Adolescents and Could Not be Eliminated with Enhanced Instructions

Journal of Child and Adolescent Psychopharmacology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 12, 2025

Objective: Self-report questionnaires are common for measuring posttraumatic stress disorder (PTSD). The experience of life threat-Criterion A-serves a gatekeeper function diagnosing PTSD, and evidence suggests false positives on questionnaires. It remains unknown how they whether extra instructions can reduce them. Methods: present study assessed 42 youths, 10-17 years age, from clinic setting. Youths parents completed regular PTSD then enhanced versions with more detailed examples Criterion A non-Criterion events. Parents semistructured interview as the verification true versus positives. Results: In full sample, endorsed 41 children 45 positive mean was significantly greater than zero both children. 59 138 symptoms. When events were endorsed, this associated symptoms An questionnaire failed to sample. Discussion: occurrence caution is warranted when interpreting estimates questionnaire-based research about prevalence PTSD. While attempt eliminate not fully successful, there may be other useful enhancements consider in future research.

Язык: Английский

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Demographic, occupational factors and pandemic-related stressors associated with heightened mental health difficulties among UK health and social care workers supported by regional Resilience Hubs during the COVID-19 pandemic

BMJ Open, Год журнала: 2025, Номер 15(2), С. e082817 - e082817

Опубликована: Фев. 1, 2025

Background During the COVID-19 pandemic, 40 mental health and well-being hubs were funded in England to support social care staff affected by pandemic. Aims To describe characteristics of accessing four for identify associated with clinically significant difficulties work functioning. Method Routinely collected screening data analysed from 1973 individuals across 4 hubs, including health, demographic occupational pandemic-related stressors. Factors identified via logistic regression. Results Most hub clients as white women who worked UK National Health Service; other groups less well represented. Hub reported high levels difficulties: 60% had severe often co-occurring (ie, depression, anxiety, post-traumatic stress disorder or alcohol use) 80% significantly impaired Younger age, disability status, identifying a minority ethnic group, sexual orientations excluding heterosexual higher likelihood having difficulties. Suffering financial loss during prepandemic emotional concerns most consistent factors Conclusions The supported Outreach engagement under-represented should be undertaken address potential barriers service access. findings add knowledge base on needs workforce planning response future crises.

Язык: Английский

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Supporting the well-being of nurses working with trauma

Nursing Standard, Год журнала: 2025, Номер unknown

Опубликована: Март 3, 2025

The nursing profession has long been associated with exposure to traumatic experiences, including mental health crises, violence, emergencies and death. coronavirus disease 2019 (COVID-19) pandemic amplified the importance of recognising effects that working trauma can have on nurses' physical psychological well-being, highlighting urgency addressing this issue. This article explores concept its various manifestations, such as post-traumatic stress disorder (PTSD) secondary stress, which are increasingly prevalent among nurses. It also considers adaptive maladaptive coping mechanisms may be adopted by nurses, discusses effectiveness limitations debriefing interventions. author emphasises need for holistic support mechanisms, ongoing monitoring tailored interventions safeguard well-being. Recommendations practice include enhancing nurse education management, improving practices fostering organisational responsibility supporting These measures essential ensure sustainability workforce quality care provided patients.

Язык: Английский

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Factors associated with depression, anxiety, stress, PTSD, and fatigue of medical staff during the COVID-19 pandemic in Shanghai: a two-phase cross-sectional study

Brazilian Journal of Medical and Biological Research, Год журнала: 2025, Номер 58

Опубликована: Янв. 1, 2025

During the COVID-19 pandemic in Shanghai, medical workers were more vulnerable to psychological problems. This two-phase cross-sectional survey was conducted by online questionnaires investigate symptoms of depression, anxiety, stress, post-traumatic stress disorder (PTSD), and fatigue healthcare during outbreak after resumption work production Shanghai. The questionnaire included Depression Anxiety Stress Scale-21 (DASS-21), Impact Event Scale-Revised (IES-R), Fatigue Assessment Instrument (FAI). In Phase I (n=2192), prevalence PTSD among staff 45.48, 41.93, 20.35, 75.55%. II (n=1031), resumed 19.79, 21.44, 28.23, 12.22%, respectively. had a mean score 121.23±45.776 144.73±44.141 II. Binary logistic regression identified risk factors associated with this status: personal familial chronic disease history; occupation, including doctor, nurse, or administrative staff; working fever clinic, infectious department, emergency intensive care unit, hemodialysis room, clinical laboratory; experience 3-6 years 7-10 years; involvement nucleic acid sampling team. Medical self-reported comparatively high rates and, especially, Our study indicated that it appeared overall mental health improved somewhat. Nevertheless, level exhibited still cannot be ignored.

Язык: Английский

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The relationship between language features and PTSD symptoms: a systematic review and meta-analysis

Frontiers in Psychiatry, Год журнала: 2025, Номер 16

Опубликована: Март 31, 2025

Objective The aim of this study is to investigate the relationship between language features and symptoms Post-Traumatic Stress Disorder (PTSD) determine if can serve as a reliable index for rapid screening assessing PTSD. Methods A comprehensive literature search was performed using Pubmed, Embase, Cochrane Central Register Controlled Trials, Web Science, Ovid databases, augmented by backward reference tracking, gather pertinent concerning traumatic stress disorders published until August 2024. Results Twelve observational studies were included, comprising cumulative sample size 5,706 cases. Various analysis tools, such Linguistic Inquiry Word Count (LIWC), manual coding, machine learning techniques, employed in studies. Meta-analysis findings revealed positive correlation death-related words PTSD (OR 1.32, 95%CI 1.10 1.59, I² 79.4%, p = 0.004 ), well significant correlations negative emotion 1.21, 1.11 30.5%, < 0.001 anger-related 1.14, 1.17, 0.0%, word count 1.20, 1.09 1.31, 11.2%, ). Additionally, observed body-related hyperarousal 1.26, 1.15 1.37, intrusive 1.40, 1.16 1.68, avoidance (OR1.29, 1.21 Death-related 1.16, 95% CI 1.08 1.25, ) 1.18, 1.27, Conversely, no found use related sadness, anxiety, emotions, first-person pronouns, sensory, cognitive-related symptoms. Conclusion words, Language hold promise indicator PTSD; however, further research warranted their with across various cultural contexts, genders, types trauma. Systematic Review Registration https://www.crd.york.ac.uk/PROSPERO , identifier CRD42024528621.

Язык: Английский

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