Organic Peroxides in Aerosol: Key Reactive Intermediates for Multiphase Processes in the Atmosphere

Chemical Reviews, Год журнала: 2023, Номер 123(4), С. 1635 - 1679

Опубликована: Янв. 11, 2023

Organic peroxides (POs) are organic molecules with one or more peroxide (−O–O−) functional groups. POs commonly regarded as chemically labile termination products from gas-phase radical chemistry and therefore serve temporary reservoirs for oxidative radicals (HOx ROx) in the atmosphere. Owing to their ubiquity, active gas-particle partitioning behavior, reactivity, key reactive intermediates atmospheric multiphase processes determining life cycle (formation, growth, aging), climate, health impacts of aerosol. However, there remain substantial gaps origin, molecular diversity, fate due complex nature dynamic behavior. Here, we summarize current understanding on POs, a focus identification quantification, state-of-the-art analytical developments, molecular-level formation mechanisms, chemical transformation pathways, well environmental impacts. We find that interactions SO2 transition metal ions generally fast PO pathways liquid water, lifetimes estimated be minutes hours, while hydrolysis is particularly important α-substituted hydroperoxides. Meanwhile, photolysis thermolysis likely minor sinks POs. These distinctly different fates, such reaction OH radicals, which highlights need understand By summarizing advances remaining challenges investigation propose future research priorities regarding fate,

Язык: Английский

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Effects of Acidity on Reactive Oxygen Species Formation from Secondary Organic Aerosols

ACS Environmental Au, Год журнала: 2022, Номер 2(4), С. 336 - 345

Опубликована: Апрель 29, 2022

Reactive oxygen species (ROS) play a critical role in the chemical transformation of atmospheric secondary organic aerosols (SOA) and aerosol health effects by causing oxidative stress vivo. Acidity is an important physicochemical property aerosols, but its on ROS formation from SOA have been poorly characterized. By applying electron paramagnetic resonance spin-trapping technique Diogenes chemiluminescence assay, we find highly distinct radical yields composition at different pH values range 1–7.4 generated oxidation isoprene, α-terpineol, α-pinene, β-pinene, toluene, naphthalene. We observe that isoprene has substantial hydroxyl (•OH) neutral pH, which are 1.5–2 times higher compared to acidic conditions total yields. Superoxide (O2•–) found be dominant all types SOAs lower pH. At α-terpineol exhibits yield carbon-centered radicals, while no observed aromatic SOA. Further experiments with model compounds show decomposition peroxide leading may suppressed due acid-catalyzed rearrangement peroxides. also 1.5–3 molar hydrogen (H2O2) biogenic SOA, likely enhanced α-hydroxyhydroperoxides quinone redox cycling, respectively. These findings bridge gap understanding mechanisms kinetics physiological environments.

Язык: Английский

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Dynamic Wood Smoke Aerosol Toxicity during Oxidative Atmospheric Aging

Environmental Science & Technology, Год журнала: 2023, Номер 57(3), С. 1246 - 1256

Опубликована: Янв. 11, 2023

Wildfires are a major source of biomass burning aerosol to the atmosphere, with their incidence and intensity expected increase in warmer future climate. However, toxicity evolution organic (BBOA) during atmospheric aging remains poorly understood. In this study, we report unique set chemical toxicological metrics BBOA from pine wood smoldering multiphase by gas-phase hydroxyl radicals (OH). Both fresh OH-aged show activity relevant adverse health outcomes. The results two acellular assays (DTT DCFH) significant oxidative potential (OP) reactive oxygen species (ROS) formation BBOA. Also, radical concentrations assessed electron paramagnetic resonance (EPR) spectroscopy increased 50% following heterogeneous aging. This enhancement was accompanied transition predominantly carbon-centered (85%) oxygen-centered (76%) aged aerosols trigger prominent antioxidant defense

Язык: Английский

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Reactive Oxygen Species Formation and Peroxide and Carbonyl Decomposition in Aqueous Photolysis of Secondary Organic Aerosols

Environmental Science & Technology, Год журнала: 2024, Номер 58(10), С. 4716 - 4726

Опубликована: Фев. 27, 2024

The mechanism and kinetics of reactive oxygen species (ROS) formation when atmospheric secondary organic aerosol (SOA) is exposed to solar radiation are poorly understood. In this study, we combined an in situ UV–vis irradiation system with electron paramagnetic resonance (EPR) spectroscopy characterize the photolytic ROS aqueous extracts SOA formed by oxidation isoprene, α-pinene, α-terpineol, toluene. We observed substantial free radicals, including •OH, superoxide (HO2•), radicals (R•/RO•) upon irradiation. Compared dark conditions, radical yield was enhanced a factor ∼30 for •OH 2–10 emergence radicals. Total peroxide measurements showed decreases contents after photoirradiation, indicating that peroxides can be important source A liquid chromatography interfaced high-resolution mass spectrometry used detect number form adducts spin trap, BMPO. types detected photolysis model compounds indicated carbonyls Norrish type I mechanisms plays role formation. serves as driving force cloud fog processing SOA.

Язык: Английский

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Magnetic iron oxide nanoparticles: An emerging threat for the environment and human health

Journal of Environmental Sciences, Год журнала: 2024, Номер 152, С. 188 - 202

Опубликована: Май 7, 2024

Язык: Английский

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Secondary Organic Aerosol Generated from Biomass Burning Emitted Phenolic Compounds: Oxidative Potential, Reactive Oxygen Species, and Cytotoxicity

Environmental Science & Technology, Год журнала: 2024, Номер 58(19), С. 8194 - 8206

Опубликована: Апрель 29, 2024

Phenolic compounds are largely emitted from biomass burning (BB) and have a significant potential to form SOA (Phc-SOA). However, the toxicological properties of Phc-SOA remain unclear. In this study, phenol guaiacol were chosen as two representative phenolic gases in BB plumes, water-soluble components their generated under different photochemical ages NOx levels investigated. contribute greatly oxidative (OP) biomass-burning SOA. OH-adducts (e.g., 2-methoxyhydroquinone) identified (GSOA) with high OP. The addition nitro groups 2,5-dimethyl-1,4-benzoquinone, surrogate quinone compound Phc-SOA, increased its toxicity both (PSOA) GSOA vitro human alveolar epithelial cells decreased aging terms cell death cellular reactive oxygen species (ROS), possibly due more ring-opening products relatively low toxicity. influence was consistent between ROS for but not PSOA, indicating that production does necessarily represent all processes contributing caused by PSOA. Combining acellular assays can provide comprehensive understanding aerosol properties.

Язык: Английский

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Influence of aerosol acidity and organic ligands on transition metal solubility and oxidative potential of fine particulate matter in urban environments

The Science of The Total Environment, Год журнала: 2023, Номер 906, С. 167405 - 167405

Опубликована: Сен. 29, 2023

Язык: Английский

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Aging Effects on the Toxicity Alteration of Different Types of Organic Aerosols: A Review

Current Pollution Reports, Год журнала: 2023, Номер 9(3), С. 590 - 601

Опубликована: Июнь 16, 2023

Язык: Английский

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Oxidized and Unsaturated: Key Organic Aerosol Traits Associated with Cellular Reactive Oxygen Species Production in the Southeastern United States

Environmental Science & Technology, Год журнала: 2023, Номер 57(38), С. 14150 - 14161

Опубликована: Сен. 12, 2023

Exposure to ambient fine particulate matter (PM2.5) is associated with millions of premature deaths annually. Oxidative stress through overproduction reactive oxygen species (ROS) a possible mechanism for PM2.5-induced health effects. Organic aerosol (OA) dominant component PM2.5 worldwide, yet its role in toxicity poorly understood due chemical complexity. Here, integrated cellular ROS measurements and detailed multi-instrument characterization PM urban southeastern United States, we show that oxygenated OA (OOA), especially more-oxidized OOA, the main type production. We further reveal highly unsaturated containing carbon–oxygen double bonds aromatic rings OOA are major contributors These results highlight key features driving toxicity. As ubiquitous abundant atmosphere, this emphasizes need understand sources processing when formulating effective strategies mitigate impacts.

Язык: Английский

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Change of Composition, Source Contribution, and Oxidative Effects of Environmental PM_2.5 in the Respiratory Tract

Environmental Science & Technology, Год журнала: 2023, Номер 57(31), С. 11605 - 11611

Опубликована: Июль 24, 2023

Fine particulate matter is a leading air pollutant, and its composition profile relates to sources health effects. The human respiratory tract hosts warmer more humid microenvironment in contrast with peripheral environments. However, how the impacts transformation of environmental PM2.5 once they are inhaled consequently changes source contribution effects unknown. Here, we show that can make these properties reaching lung different from PM2.5. We found via an vitro model warm conditions drive desorption nitrate (about 60%) ammonium 31%) out during inhalation process profiles for tract-deposited as suggested 11 Chinese cities 12 US cities. also observed oxidative potential, one main risk causes PM2.5, increases by 41% after travels through model. Our results reveal differs This work provides starting point health-oriented apportionment, physiology-based evaluation, cost-effective control pollution.

Язык: Английский

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