Synthesis of medium-sized benzo[b]azocines and benzo[b]azonines by photoinduced 8-/9-endo sulfonyl-cyclization

Science China Chemistry, Год журнала: 2023, Номер 66(8), С. 2309 - 2316

Опубликована: Июль 24, 2023

Язык: Английский

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Trifluoromethoxylation/trifluoromethylthiolation/trifluoro- methylselenolation strategy for the construction of heterocycles

Chinese Chemical Letters, Год журнала: 2022, Номер 34(5), С. 108045 - 108045

Опубликована: Дек. 8, 2022

Язык: Английский

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Chemoselective electrochemical seleno-cyclization of dienes to medium-sized benzo[b]azocines

Chinese Chemical Letters, Год журнала: 2023, Номер 35(2), С. 109058 - 109058

Опубликована: Сен. 10, 2023

Язык: Английский

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Metal-free β,γ-C(sp³)–H difunctionalization of propanols: DMP-initiated asymmetric spirocyclopropanation

Chemical Communications, Год журнала: 2024, Номер 60(26), С. 3579 - 3582

Опубликована: Янв. 1, 2024

This work reports a one-pot asymmetric synthesis of spirocyclopropyl propionaldehydes/propanols via β,γ-bifunctionalization propanols through the synergistic effect secondary amine catalyst and an oxidant.

Язык: Английский

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Regioselective Homolytic C²–H Borylation of Unprotected Adenosine and Adenine Derivatives via Minisci Reaction

Journal of the American Chemical Society, Год журнала: 2024, Номер 146(31), С. 21428 - 21441

Опубликована: Июль 25, 2024

A Minisci-type borylation of unprotected adenosine, adenine nucleotide, and adenosine analogues was successfully achieved through photocatalysis or thermal activation. Despite the challenges posed by presence two potential reactive sites (C

Язык: Английский

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Photo/Electrochemical‐Mediated C(sp³)−H Bond Functionalization of (Thio)Ethers

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(17)

Опубликована: Март 11, 2024

Abstract Molecules containing ether skeletons are widely present in drugs, natural products, functional materials, and life science. Direct C(sp 3 )−H bond functionalization is considered a powerful strategy for the construction of novel derivatives. Photo‐/electro‐chemical technology relatively green sustainable synthesis method, which opens up broad application prospect field direct bonds. In recent years, photo‐/electro‐mediated alkylation, arylation, alkynylation, esterification, mercaptoylation, sulfidation, amination ethers have been extensively studied. this review, research progress compounds from 2014 to 2023 systematically reviewed, scope, limitations, mechanisms some reactions discussed.

Язык: Английский

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Photocatalyst-free visible-light-induced highly selective acylation of purine nucleosides at the C6 position

Chemical Communications, Год журнала: 2023, Номер 59(26), С. 3910 - 3913

Опубликована: Янв. 1, 2023

A protocol for visible-light-induced C-H acylation selectively at the C6 position of purine nucleosides with aldehydes under photocatalyst-free conditions was established herein. This allows green, mild, and efficient functionalization various a broad range alkyl aryl aldehydes.

Язык: Английский

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Synthesis of 3(2H)-furanone derivatives: p-TsOH/halotrimethylsilane promoted cycloketonization of γ-hydroxyl ynones

Organic & Biomolecular Chemistry, Год журнала: 2023, Номер 21(43), С. 8744 - 8748

Опубликована: Янв. 1, 2023

A halotrimethylsilane facilitated cycloketonization of γ -hydroxyl ynones is detailed for one-step synthesis polysubstituted 3(2 H )-furanone products.

Язык: Английский

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Photoinduced sulfonylation cyclization to medium-sized benzo[b]azocine and mechanistic insight

Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(13), С. 3313 - 3320

Опубликована: Янв. 1, 2023

A novel light induced 8-endo sulfonyl cyclization to medium-sized benzo[ b ]azocines is developed. DFT calculations rationalize the rate-determining step and chemoselectivity observed in this transformation.

Язык: Английский

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Regioselective Synthesis of Unsymmetrical Vicinal Diamines via Azidoimination of Alkenes with TMSN₃ and Ketimines

Organic Letters, Год журнала: 2023, Номер 25(48), С. 8716 - 8721

Опубликована: Ноя. 22, 2023

2-Azidoimines are versatile precursors to value-added vicinal unsymmetrical diamines, which among the most common motifs in biologically active compounds. Herein, we report their operationally simple synthesis through a highly regioselective intermolecular azidoamination of olefins under metal-free conditions. The approach proceeded azide and iminyl, two differentiated N-centered radicals. synthetic potential protocols was further established via condensation/amination sequential cascade chemoselective, orthogonal transformations access primary diamines.

Язык: Английский

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