Organic & Biomolecular Chemistry,
Год журнала:
2023,
Номер
21(23), С. 4794 - 4800
Опубликована: Янв. 1, 2023
The
iron(III)
salen
complex
(R,R)-N,N'-bis(salicylidene)-1,2-cyclohexanediamineiron(III)
chloride
has
been
developed
as
a
catalyst
for
the
acceptorless
dehydrogenation
of
alcohols.
catalyzes
direct
synthesis
imines
in
good
yields
from
different
primary
alcohols
and
amines
with
liberation
hydrogen
gas.
mechanism
investigated
experimentally
labelled
substrates
theoretically
density
functional
theory
calculations.
In
contrast
to
corresponding
manganese(III)
salen-catalyzed
dehydrogenation,
it
not
possible
identify
homogeneous
catalytic
pathway
iron
complex.
Instead,
poisoning
experiments
trimethylphosphine
mercury
indicated
that
catalytically
active
species
are
heterogeneous
small
particles.
ACS Catalysis,
Год журнала:
2023,
Номер
13(22), С. 15013 - 15053
Опубликована: Ноя. 6, 2023
Methanol
is
a
fundamental
feedstock
and
widely
used
in
the
chemical
petroleum
industries.
It
can
serve
as
C1
source
to
make
variety
of
C–C
C–N
bond
formation
dehydrogenative
coupling
products,
which
have
important
applications
natural
products
drug
discovery.
A
high
hydrogen
content
(12.5
wt%)
methanol
makes
it
an
effective
H2
donor
for
transfer
hydrogenation
various
reducible
functional
groups.
plethora
transition
metal-based
processes
been
developed
using
methanol.
Notably,
recent
review
articles
focused
on
aspect
However,
more
updated
that
examines
challenges
both
C1-source
H2-source
organic
transformations
contributing
concept
economy
has
not
presented
yet.
This
Review
summarizes
(homogeneous,
heterogeneous,
photo-)
catalyst
system
C-,
N-,
O-methylation
ketones,
alcohols,
amides,
nitriles,
heterocyclic
compounds,
sulfones,
amines,
sulfonamides
direct
N-methylation
nitro
compounds
under
borrowing
strategy
N-formylation
amines
acceptorless
dehydrogenation
source.
also
covers
insights
into
reaction
mechanisms
role
carefully
selected
ligands
metal
catalysis
activation
incorporation
-CD3,
methylation
molecules.
Moreover,
describes
groups
such
aldehydes,
alkynes,
with
detail.
Organic Letters,
Год журнала:
2024,
Номер
26(27), С. 5788 - 5793
Опубликована: Июнь 27, 2024
Stereocontrolled
oxa-Michael
additions
are
challenging,
given
the
high
reversibility
of
process,
which
ultimately
leads
to
racemization
newly
formed
stereocenters.
When
iron-catalyzed
borrowing
hydrogen
from
allylic
alcohols
was
combined
with
a
stereocontrolled
organocatalytic
addition,
wide
array
chiral
tetrahydropyrans
were
efficiently
prepared.
The
reaction
could
be
performed
in
diastereoselective
manner
pre-existing
stereocenters
or
enantioselectively
achiral
substrates.
key
success
reactivity
iron
complex,
selective
for
alcohol
dehydrogenation
and
irreversibly
led
final
product.
ACS Catalysis,
Год журнала:
2024,
Номер
14(10), С. 7795 - 7805
Опубликована: Май 6, 2024
Discovering
active,
cheap
iron
complexes
for
eco-compatible
borrowing
hydrogen
transformations
constitutes
a
real
challenge.
In
this
context,
we
developed
family
of
isonitrile-substituted
cyclopentadienone
complexes.
They
were
successfully
applied
in
traditional
amine
alkylation
with
alcohols
and,
notably,
the
development
photoactivated
multicatalytic
enantioselective
allylic
alcohol
functionalization.
Of
importance,
catalyst
showing
greater
activity
under
photoirradiation
differs
from
one
most
active
conventional
using
chemical
activation.
This
underscores
importance
incorporating
isonitrile
ligands
readily
customizable
manner,
resulting
catalysts
complementary
reactivities.
The
characterization
their
physical
properties
was
complemented
by
density
functional
theory
calculations
to
enhance
our
understanding
behavior.
Given
distinctive
disclosed
catalysts,
application
is
poised
pave
way
exploring
challenging
reactivities
related
catalytic
processes.
Green Chemistry,
Год журнала:
2024,
Номер
26(14), С. 8161 - 8203
Опубликована: Янв. 1, 2024
The
strategic
installation
of
the
“magic
methyl”
group
has
become
highly
desirable
for
drug
discovery.
This
review
summarized
recent
photochemical
and
electrochemical
strategies
in
installing
methyl
group.
Chinese Journal of Organic Chemistry,
Год журнала:
2023,
Номер
43(4), С. 1386 - 1386
Опубликована: Янв. 1, 2023
In
recent
years,
the
development
and
application
of
transition
metal
ruthenium
or
iridium
complexes
based
photocatalysts
have
opened
up
a
new
research
field
for
organic
synthesis,
which
provides
mild
efficient
strategies
construction
chemical
bonds
transformations.In
order
to
enrich
types
photocatalysts,
broaden
scope
photocatalysis,
develop
green
sustainable
chemistry,
some
low-cost
easily
available
organometallic
with
copper
iron
were
applied
as
recently.Iron-complexes
feature
non-toxicity,
rich
variety,
unique
property
charge
transfer
from
ligands
metals,
enable
them
show
extraordinary
capability
in
photocatalytic
synthesis.According
different
reaction
types,
this
review
focuses
on
photoinduced
iron-catalysis
synthesis
including
C-H
bond
functionalization,
C-C
bifunctionalization
alkenes,
cross-coupling
reaction,
decarboxylative
selective
oxidation
reduction.
Organometallics,
Год журнала:
2023,
Номер
42(14), С. 1784 - 1792
Опубликована: Июнь 1, 2023
The
reductive
amination
reaction
of
imines
catalyzed
by
Knölker-type
iron
complexes
under
hydrogen
at
high
pressure
is
very
interesting
in
synthetic
terms.
This
type
an
important
catalytic
challenge,
since
harsh
conditions
are
necessary
and
do
not
occur
easily.
In
a
previous
work
(
Organometallics
2022,
41,
1204−1215),
we
carried
out
computational
study
the
mechanism
showing
that
electron-withdrawing
groups
(EWGs)
attached
to
cyclopentadienone
favor
imines.
synthesis
with
cyclopentadienones
having
EWGs
straightforward,
direct
bonding
on
would
lead
but
undesired
dimerization.
A
possible
solution
consists
addition
phenyl
substituents
these
catalysts
then
introduction
rings.
We
have
performed
studies
using
density
functional
theory
(DFT)
for
analyze
efficiency
such
approach.
found
some
facilitate
result
has
been
later
confirmed
experimentally,
therefore,
computationally
designed
new
improve
performances
previously
known
complexes.
