Photoredox catalysis leading to triazolo-quinoxalinones at room temperature: selectivity of the rate determining step DOI
Roger Monreal‐Corona, Emili Besalú, Anna Pla‐Quintana

et al.

Organic & Biomolecular Chemistry, Journal Year: 2022, Volume and Issue: 20(47), P. 9330 - 9336

Published: Jan. 1, 2022

The mechanism for the photoredox catalysed synthesis of triazoloquinoxalinones is unveiled by DFT calculations. Predictive chemistry gives recipe substituents, sterically and electronically, can fit to perform reaction at room temperature.

Language: Английский

Research progress in electrochemical/photochemical utilization of methanol as a C1 source DOI
Haitao Tang, Yong-Zhou Pan, Ying‐Ming Pan

et al.

Green Chemistry, Journal Year: 2023, Volume and Issue: 25(21), P. 8313 - 8327

Published: Jan. 1, 2023

This review highlights the recent advances in various electrochemical and photochemical reactions using methanol as a sustainable C1 source.

Language: Английский

Citations

39
Multi-Functionality of Methanol in Sustainable Catalysis: Beyond Methanol Economy DOI
Ganesan Sivakumar, Rohit Kumar, Vinita Yadav

et al.

ACS Catalysis, Journal Year: 2023, Volume and Issue: 13(22), P. 15013 - 15053

Published: Nov. 6, 2023

Methanol is a fundamental feedstock and widely used in the chemical petroleum industries. It can serve as C1 source to make variety of C–C C–N bond formation dehydrogenative coupling products, which have important applications natural products drug discovery. A high hydrogen content (12.5 wt%) methanol makes it an effective H2 donor for transfer hydrogenation various reducible functional groups. plethora transition metal-based processes been developed using methanol. Notably, recent review articles focused on aspect However, more updated that examines challenges both C1-source H2-source organic transformations contributing concept economy has not presented yet. This Review summarizes (homogeneous, heterogeneous, photo-) catalyst system C-, N-, O-methylation ketones, alcohols, amides, nitriles, heterocyclic compounds, sulfones, amines, sulfonamides direct N-methylation nitro compounds under borrowing strategy N-formylation amines acceptorless dehydrogenation source. also covers insights into reaction mechanisms role carefully selected ligands metal catalysis activation incorporation -CD3, methylation molecules. Moreover, describes groups such aldehydes, alkynes, with detail.

Language: Английский

Citations

31
The α-trideuteromethylation of arylacetonitriles with deuterated methanol via deuterium autotransfer process catalyzed by a metal-ligand bifunctional iridium catalyst DOI
Deyun Liu, Xiangchao Xu, Peng Zhang

et al.

Journal of Catalysis, Journal Year: 2024, Volume and Issue: 430, P. 115301 - 115301

Published: Jan. 18, 2024

Language: Английский

Citations

7
Iron- and Organo-Catalyzed Borrowing Hydrogen for the Stereoselective Construction of Tetrahydropyrans DOI
Anestis Alexandridis,

Thibault Rancon,

Abigail Halliday

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(27), P. 5788 - 5793

Published: June 27, 2024

Stereocontrolled oxa-Michael additions are challenging, given the high reversibility of process, which ultimately leads to racemization newly formed stereocenters. When iron-catalyzed borrowing hydrogen from allylic alcohols was combined with a stereocontrolled organocatalytic addition, wide array chiral tetrahydropyrans were efficiently prepared. The reaction could be performed in diastereoselective manner pre-existing stereocenters or enantioselectively achiral substrates. key success reactivity iron complex, selective for alcohol dehydrogenation and irreversibly led final product.

Language: Английский

Citations

6
CO to Isonitrile Substitution in Iron Cyclopentadienone Complexes: A Class of Active Iron Catalysts for Borrowing Hydrogen Strategies DOI

Gaëtan Quintil,

Léa Diebold,

Gibrael Fadel

et al.

ACS Catalysis, Journal Year: 2024, Volume and Issue: 14(10), P. 7795 - 7805

Published: May 6, 2024

Discovering active, cheap iron complexes for eco-compatible borrowing hydrogen transformations constitutes a real challenge. In this context, we developed family of isonitrile-substituted cyclopentadienone complexes. They were successfully applied in traditional amine alkylation with alcohols and, notably, the development photoactivated multicatalytic enantioselective allylic alcohol functionalization. Of importance, catalyst showing greater activity under photoirradiation differs from one most active conventional using chemical activation. This underscores importance incorporating isonitrile ligands readily customizable manner, resulting catalysts complementary reactivities. The characterization their physical properties was complemented by density functional theory calculations to enhance our understanding behavior. Given distinctive disclosed catalysts, application is poised pave way exploring challenging reactivities related catalytic processes.

Language: Английский

Citations

5
Direct use of methanol instead of formaldehyde or paraformaldehyde: Acceptorless dehydrogenative coupling for the synthesis of arylhydrazones catalyzed by a metal–ligand iridium bifunctional catalyst DOI
Beixuan Dong,

Yiqian He,

Xiangchao Xu

et al.

Journal of Catalysis, Journal Year: 2024, Volume and Issue: 438, P. 115685 - 115685

Published: Aug. 3, 2024

Language: Английский

Citations

5
Demystifying the recent photochemical and electrochemical tricks on installing the magic methyl group: A comprehensive overview DOI

Feiyang Liao,

Zenghui Wei,

Yunhao Guan

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(14), P. 8161 - 8203

Published: Jan. 1, 2024

The strategic installation of the “magic methyl” group has become highly desirable for drug discovery. This review summarized recent photochemical and electrochemical strategies in installing methyl group.

Language: Английский

Citations

4
Visible light mediated Iron-Catalyzed synthesis of C-3 alkylated Indoles, bisindolylmethanes and flavanones using alcohols DOI
Mohd Waheed, Meshari A. Alsharif, Mohammed Issa Alahmdi

et al.

Tetrahedron Letters, Journal Year: 2023, Volume and Issue: 119, P. 154428 - 154428

Published: March 3, 2023

Language: Английский

Citations

10
Nickel‐Catalyzed Chemodivergent Coupling of Alcohols: Efficient Routes to Access α,α‐Disubstituted Ketones and α‐Substituted Chalcones DOI

Sadhna Bansal,

Benudhar Punji

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: 30(15)

Published: Jan. 17, 2024

Abstract Chemodivergent (de)hydrogenative coupling of primary and secondary alcohols is achieved utilizing an inexpensive nickel catalyst, (6‐OH‐bpy)NiCl 2 . This protocol demonstrates the synthesis branched carbonyl compounds, α , ‐disubstituted ketones, ‐substituted chalcones via borrowing hydrogen strategy acceptorless dehydrogenative coupling, respectively. A wide range aryl‐based are coupled with various in this tandem dehydrogenation/hydrogenation reaction. The along KO t Bu or K CO 3 governed selectivity for formation saturated ketones chalcones. preliminary mechanistic investigation confirms reversible dehydrogenation to carbonyls metal‐ligand cooperation (MLC) involvement radical intermediates during

Language: Английский

Citations

3
Shining a light on Fe-catalyzed borrowing hydrogen alkylation DOI Creative Commons

Salma A. Elsherbeni,

Tahir Maqbool,

Md Abdul Bari

et al.

Trends in Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0