Application of 3D-Printed, PLGA-Based Scaffolds in Bone Tissue Engineering DOI Open Access

Fengbo Sun,

Xiaodan Sun,

Hetong Wang

и другие.

International Journal of Molecular Sciences, Год журнала: 2022, Номер 23(10), С. 5831 - 5831

Опубликована: Май 23, 2022

Polylactic acid-glycolic acid (PLGA) has been widely used in bone tissue engineering due to its favorable biocompatibility and adjustable biodegradation. 3D printing technology can prepare scaffolds with rich structure function, is one of the best methods obtain for repair. This review systematically summarizes research progress 3D-printed, PLGA-based scaffolds. The properties modified components are introduced detail. influence method change process analyzed. advantages disadvantages their applications illustrated by several examples. Finally, we briefly discuss limitations future development direction current materials

Язык: Английский

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects DOI
Pooyan Makvandi, Chenyu Wang, Ehsan Nazarzadeh Zare‬

и другие.

Advanced Functional Materials, Год журнала: 2020, Номер 30(22)

Опубликована: Март 17, 2020

Abstract Microbial colonization on material surfaces is ubiquitous. Biofilms derived from surface‐colonized microbes pose serious problems to the society both an economical perspective and a health concern. Incorporation of antimicrobial nanocompounds within or surface materials, by coatings, prevent microbial adhesion kill microorganisms after their attachment biofilms, represents important strategy in increasingly challenging field. Over last decade, many studies have been devoted preparing meta‐based nanomaterials that possess antibacterial, antiviral, antifungal activities combat pathogen‐related diseases. Herein, overview state‐of‐the‐art nanosized metal‐based compounds provided, including metal oxide nanoparticles as well transition nanosheets. The mechanism these nanostructures biomedical applications such catheters, implants, medical delivery systems, tissue engineering, dentistry are discussed. Their properties potential caveats cytotoxicity, diminishing efficacy, induction resistance materials incorporating reviewed provide backdrop for future research.

Язык: Английский

Процитировано

598

Advances in Antimicrobial Microneedle Patches for Combating Infections DOI
Rezvan Jamaledin,

Cynthia Kar Yung Yiu,

Ehsan Nazarzadeh Zare‬

и другие.

Advanced Materials, Год журнала: 2020, Номер 32(33)

Опубликована: Июнь 29, 2020

Abstract Skin infections caused by bacteria, viruses and fungi are difficult to treat conventional topical administration because of poor drug penetration across the stratum corneum. This results in low bioavailability drugs infection site, as well lack prolonged release. Emerging antimicrobial transdermal ocular microneedle patches have become promising medical devices for delivery various antibacterial, antifungal, antiviral therapeutics. In present review, skin anatomy its barriers along with discussed. Potential strategies designing microneedles their targeted therapy outlined. Finally, biosensing associated personalized selective toxicity toward specific microbial species

Язык: Английский

Процитировано

360

Carboxymethyl cellulose-based materials for infection control and wound healing: A review DOI

Vimala Kanikireddy,

Kokkarachedu Varaprasad, Tippabattini Jayaramudu

и другие.

International Journal of Biological Macromolecules, Год журнала: 2020, Номер 164, С. 963 - 975

Опубликована: Июль 21, 2020

Язык: Английский

Процитировано

357

3D and 4D printing in dentistry and maxillofacial surgery: Printing techniques, materials, and applications DOI
Danial Khorsandi, Amir Fahimipour, Payam Abasian

и другие.

Acta Biomaterialia, Год журнала: 2020, Номер 122, С. 26 - 49

Опубликована: Дек. 26, 2020

Язык: Английский

Процитировано

303

Recent advances in PLGA-based biomaterials for bone tissue regeneration DOI
Shue Jin, Xue Xia, Jinhui Huang

и другие.

Acta Biomaterialia, Год журнала: 2021, Номер 127, С. 56 - 79

Опубликована: Апрель 6, 2021

Язык: Английский

Процитировано

221

PLGA-Based Composites for Various Biomedical Applications DOI Open Access
Cátia Vieira Rocha, Victor Gonçalves, Milene Costa da Silva

и другие.

International Journal of Molecular Sciences, Год журнала: 2022, Номер 23(4), С. 2034 - 2034

Опубликована: Фев. 12, 2022

Polymeric materials have been extensively explored in the field of nanomedicine; within them, poly lactic-co-glycolic acid (PLGA) holds a prominent position micro- and nanotechnology due to its biocompatibility controllable biodegradability. In this review we focus on combination PLGA with different inorganic nanomaterials form nanocomposites overcome polymer’s limitations extend applications. We discuss their physicochemical properties variety well-established synthesis methods for preparation PLGA-based materials. Recent progress design biomedical applications are thoroughly discussed provide framework future research.

Язык: Английский

Процитировано

218

In vivo gene delivery mediated by non-viral vectors for cancer therapy DOI Open Access
Reza Mohammadinejad, Ali Dehshahri, Vijay Sagar Madamsetty

и другие.

Journal of Controlled Release, Год журнала: 2020, Номер 325, С. 249 - 275

Опубликована: Июль 4, 2020

Язык: Английский

Процитировано

206

4D-Printed Dynamic Materials in Biomedical Applications: Chemistry, Challenges, and Their Future Perspectives in the Clinical Sector DOI Creative Commons

Wenxian Zhou,

Zhiguang Qiao, Ehsan Nazarzadeh Zare‬

и другие.

Journal of Medicinal Chemistry, Год журнала: 2020, Номер 63(15), С. 8003 - 8024

Опубликована: Апрель 7, 2020

Most of the biomedical materials printed using 3D bioprinting are static and unable to alter/transform with dynamic changes in internal environment body. The emergence four-dimensional (4D) printing addresses this problem. By preprogramming polymer their nanocomposites, 4D is able produce desired shapes or transform functions under specific conditions stimuli better adapt surrounding environment. In review, current potential applications 4D-printed introduced different aspects field, e.g., tissue engineering, drug delivery, sensors. addition, existing limitations possible solutions discussed. Finally, along future perspective presented provide a basis for research.

Язык: Английский

Процитировано

157

Biomedical Applications of MXene‐Integrated Composites: Regenerative Medicine, Infection Therapy, Cancer Treatment, and Biosensing DOI Creative Commons
Aziz Maleki, Matineh Ghomi, Nasser Nikfarjam

и другие.

Advanced Functional Materials, Год журнала: 2022, Номер 32(34)

Опубликована: Июнь 24, 2022

Abstract MXenes (viz., transition metal carbides, carbonitrides, and nitrides) have emerged as a new subclass of 2D materials. Due to their outstanding physicochemical biological properties, gained much attention in the biomedical field recent years, including drug delivery systems, regenerative medicine, biosensing. Additionally, incorporation into hydrogels has garnered significant interest engineering an electroactive mechanical nanoreinforcer capable converting nonconductive scaffolds excellent conductors electricity with impressive effect on properties for organs tissues such cardiac, skeletal muscle, nerve. However, many questions problems remain unresolved that need be answered usher these materials toward true destiny. Thus, this review paper aims provide overview design applications MXene‐integrated composites applications, cardiac tissue engineering, wound healing, infection therapy, cancer biosensors. Moreover, current challenges limitations utilizing vivo are highlighted discussed, followed by its prospects guideline possible various futuristic applications. This article will inspire researchers, who search opportunities, using nanomaterial

Язык: Английский

Процитировано

154

Electroconductive multi-functional polypyrrole composites for biomedical applications DOI
Ehsan Nazarzadeh Zare‬, Tarun Agarwal, Atefeh Zarepour

и другие.

Applied Materials Today, Год журнала: 2021, Номер 24, С. 101117 - 101117

Опубликована: Июль 16, 2021

Язык: Английский

Процитировано

113