International Journal of Molecular Sciences,
Год журнала:
2022,
Номер
23(10), С. 5831 - 5831
Опубликована: Май 23, 2022
Polylactic
acid-glycolic
acid
(PLGA)
has
been
widely
used
in
bone
tissue
engineering
due
to
its
favorable
biocompatibility
and
adjustable
biodegradation.
3D
printing
technology
can
prepare
scaffolds
with
rich
structure
function,
is
one
of
the
best
methods
obtain
for
repair.
This
review
systematically
summarizes
research
progress
3D-printed,
PLGA-based
scaffolds.
The
properties
modified
components
are
introduced
detail.
influence
method
change
process
analyzed.
advantages
disadvantages
their
applications
illustrated
by
several
examples.
Finally,
we
briefly
discuss
limitations
future
development
direction
current
materials
Advanced Functional Materials,
Год журнала:
2020,
Номер
30(22)
Опубликована: Март 17, 2020
Abstract
Microbial
colonization
on
material
surfaces
is
ubiquitous.
Biofilms
derived
from
surface‐colonized
microbes
pose
serious
problems
to
the
society
both
an
economical
perspective
and
a
health
concern.
Incorporation
of
antimicrobial
nanocompounds
within
or
surface
materials,
by
coatings,
prevent
microbial
adhesion
kill
microorganisms
after
their
attachment
biofilms,
represents
important
strategy
in
increasingly
challenging
field.
Over
last
decade,
many
studies
have
been
devoted
preparing
meta‐based
nanomaterials
that
possess
antibacterial,
antiviral,
antifungal
activities
combat
pathogen‐related
diseases.
Herein,
overview
state‐of‐the‐art
nanosized
metal‐based
compounds
provided,
including
metal
oxide
nanoparticles
as
well
transition
nanosheets.
The
mechanism
these
nanostructures
biomedical
applications
such
catheters,
implants,
medical
delivery
systems,
tissue
engineering,
dentistry
are
discussed.
Their
properties
potential
caveats
cytotoxicity,
diminishing
efficacy,
induction
resistance
materials
incorporating
reviewed
provide
backdrop
for
future
research.
Advanced Materials,
Год журнала:
2020,
Номер
32(33)
Опубликована: Июнь 29, 2020
Abstract
Skin
infections
caused
by
bacteria,
viruses
and
fungi
are
difficult
to
treat
conventional
topical
administration
because
of
poor
drug
penetration
across
the
stratum
corneum.
This
results
in
low
bioavailability
drugs
infection
site,
as
well
lack
prolonged
release.
Emerging
antimicrobial
transdermal
ocular
microneedle
patches
have
become
promising
medical
devices
for
delivery
various
antibacterial,
antifungal,
antiviral
therapeutics.
In
present
review,
skin
anatomy
its
barriers
along
with
discussed.
Potential
strategies
designing
microneedles
their
targeted
therapy
outlined.
Finally,
biosensing
associated
personalized
selective
toxicity
toward
specific
microbial
species
International Journal of Molecular Sciences,
Год журнала:
2022,
Номер
23(4), С. 2034 - 2034
Опубликована: Фев. 12, 2022
Polymeric
materials
have
been
extensively
explored
in
the
field
of
nanomedicine;
within
them,
poly
lactic-co-glycolic
acid
(PLGA)
holds
a
prominent
position
micro-
and
nanotechnology
due
to
its
biocompatibility
controllable
biodegradability.
In
this
review
we
focus
on
combination
PLGA
with
different
inorganic
nanomaterials
form
nanocomposites
overcome
polymer’s
limitations
extend
applications.
We
discuss
their
physicochemical
properties
variety
well-established
synthesis
methods
for
preparation
PLGA-based
materials.
Recent
progress
design
biomedical
applications
are
thoroughly
discussed
provide
framework
future
research.
Journal of Medicinal Chemistry,
Год журнала:
2020,
Номер
63(15), С. 8003 - 8024
Опубликована: Апрель 7, 2020
Most
of
the
biomedical
materials
printed
using
3D
bioprinting
are
static
and
unable
to
alter/transform
with
dynamic
changes
in
internal
environment
body.
The
emergence
four-dimensional
(4D)
printing
addresses
this
problem.
By
preprogramming
polymer
their
nanocomposites,
4D
is
able
produce
desired
shapes
or
transform
functions
under
specific
conditions
stimuli
better
adapt
surrounding
environment.
In
review,
current
potential
applications
4D-printed
introduced
different
aspects
field,
e.g.,
tissue
engineering,
drug
delivery,
sensors.
addition,
existing
limitations
possible
solutions
discussed.
Finally,
along
future
perspective
presented
provide
a
basis
for
research.
Advanced Functional Materials,
Год журнала:
2022,
Номер
32(34)
Опубликована: Июнь 24, 2022
Abstract
MXenes
(viz.,
transition
metal
carbides,
carbonitrides,
and
nitrides)
have
emerged
as
a
new
subclass
of
2D
materials.
Due
to
their
outstanding
physicochemical
biological
properties,
gained
much
attention
in
the
biomedical
field
recent
years,
including
drug
delivery
systems,
regenerative
medicine,
biosensing.
Additionally,
incorporation
into
hydrogels
has
garnered
significant
interest
engineering
an
electroactive
mechanical
nanoreinforcer
capable
converting
nonconductive
scaffolds
excellent
conductors
electricity
with
impressive
effect
on
properties
for
organs
tissues
such
cardiac,
skeletal
muscle,
nerve.
However,
many
questions
problems
remain
unresolved
that
need
be
answered
usher
these
materials
toward
true
destiny.
Thus,
this
review
paper
aims
provide
overview
design
applications
MXene‐integrated
composites
applications,
cardiac
tissue
engineering,
wound
healing,
infection
therapy,
cancer
biosensors.
Moreover,
current
challenges
limitations
utilizing
vivo
are
highlighted
discussed,
followed
by
its
prospects
guideline
possible
various
futuristic
applications.
This
article
will
inspire
researchers,
who
search
opportunities,
using
nanomaterial
