Biosensors and Bioelectronics, Год журнала: 2023, Номер 241, С. 115647 - 115647
Опубликована: Сен. 4, 2023
Язык: Английский
Sensors and Actuators B Chemical, Год журнала: 2024, Номер 417, С. 136160 - 136160
Опубликована: Июнь 18, 2024
Язык: Английский
Процитировано
8
Gels, Год журнала: 2025, Номер 11(4), С. 254 - 254
Опубликована: Март 27, 2025
This paper comprehensively reviews the latest advances in hydrogel-based continuum soft robots. Hydrogels exhibit exceptional flexibility and adaptability compared to traditional robots reliant on rigid structures, making them ideal as biomimetic robotic skins platforms for constructing highly accurate, real-time responsive sensory interfaces. The article systematically summarizes recent research developments across several key dimensions, including application domains, fabrication methods, actuator technologies, sensing mechanisms. From an perspective, span healthcare, manufacturing, agriculture. Regarding techniques, extensively explores crosslinking additive microfluidics, other related processes. Additionally, categorizes thoroughly discusses various actuators solute/solvent variations, pH, chemical reactions, temperature, light, magnetic fields, electric hydraulic/electro-osmotic stimuli, humidity. It also details strategies designing implementing diverse sensors, strain, pressure, humidity, conductive, magnetic, thermal, gas, optical, multimodal sensors. Finally, offers in-depth discussion of prospective applications robots, particularly emphasizing their potential medical industrial fields. Concluding remarks include a forward-looking outlook highlighting future challenges promising directions.
Язык: Английский
Процитировано
0
Analytical Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Апрель 9, 2025
Early detection and treatment of Streptococcus pneumoniae (SPN) is crucial for patients. However, since nucleic acid testing relies on large-scale equipment specialized operators, challenges remain accurate, fast, low-cost SPN detection. Here, we present a point-of-care (POCT) device rapid accurate based low-frequency optical signal enhancement cluster regularly interspaced short palindromic repeats (CRISPR). The spotlight tube enables the fluorescence signal, while combination an artificial intelligence-assisted autoexposure algorithm homomorphic filtering image processing method improves signal-to-noise ratio image, thus realizing highly sensitive Nucleic identification performed using CRISPR-based crRNAs, fluorescent probes were constructed against IytA gene SPN. And they showed high specificity sensitivity gene. This demonstrated excellent in detecting developed strategy. threshold reached 0.1 fM, single time was only 40 min. Specificity validated clinical samples, test 100% agreement with quantitative polymerase chain reaction results from samples. provides device, which, novel DNA probe SPN, indicator option POCT
Язык: Английский
Процитировано
0
Chemical Engineering Journal, Год журнала: 2025, Номер 514, С. 163097 - 163097
Опубликована: Май 3, 2025
Язык: Английский
Процитировано
0
Talanta, Год журнала: 2025, Номер 295, С. 128250 - 128250
Опубликована: Май 4, 2025
Язык: Английский
Процитировано
0
ACS Sensors, Год журнала: 2023, Номер 8(8), С. 3104 - 3115
Опубликована: Июль 21, 2023
The clinical evidence has proven that valvular stenosis is closely related to many vascular diseases, which attracts great academic attention the corresponding pathological mechanisms. investigation expected benefit from further development of an in vitro model tunable for bio-mimicking progressive and enables accurate optical recognition complex blood flow. Here, we develop a valve-adjustable optofluidic bio-imaging platform fulfill it. Specifically, bionic valve was designed with situ soft membrane, internal air-pressure chamber could be regulated inside out bio-mimic stenosis. developed imaging algorithm enhances details flow allows quantitative analysis. In prospective study, examined effect on hemodynamics within typical physiological range veins by this way, where inhomogeneity local enhancement altered field were precisely described differences quantified. effectiveness consistency results validated through statistical addition, tested it fluorescence noticed its good performance fluorescent tracing clotting process. virtue theses merits, system should able contribute mechanism investigation, pharmaceutical development, therapeutics stenosis-related diseases.
Язык: Английский
Процитировано
6
ACS Sensors, Год журнала: 2024, Номер 9(3), С. 1592 - 1601
Опубликована: Март 13, 2024
The quantitative exploration of cellular osmotic responses and a thorough analysis pressure-responsive behaviors are poised to offer novel clinical insights into current research. This underscores paradigm shift in the long-standing approach colorimetric measurements triggered by red cell lysis. In this study, we engineered purpose-driven optofluidic platform facilitate goal. Specifically, creating photocurable hydrogel traps surmounts persistent challenge─optical signal interference from fluid disturbances. achievement ensures stable spatial phase cells acquisition optical signals for accurate response at single-cell level. Leveraging multigradient microfluidic system, constructed gradient developed an imaging recognition algorithm, empowering comprehensive behaviors. Notably, system has successfully precisely analyzed individual clustered within dimension. Prospective testing further substantiated its feasibility performance that it demonstrates accuracy 92% discriminating complete hemolysis values (n = 25) 100% identifying initial 25). Foreseeably, strategy should promise advance pressure-related analysis, benefiting investigation diagnosis related blood diseases, quality, drug development, etc.
Язык: Английский
Процитировано
2
Lab on a Chip, Год журнала: 2023, Номер 23(19), С. 4352 - 4365
Опубликована: Янв. 1, 2023
A magnetic–microfluidic device integrated with multi-wells capable of culturing mammalian cells is developed for concentration-dependent compartmentalization anticancer-drugs and testing their efficacy.
Язык: Английский
Процитировано
5
Biosensors and Bioelectronics, Год журнала: 2023, Номер 241, С. 115647 - 115647
Опубликована: Сен. 4, 2023
Язык: Английский
Процитировано
4