Transgender Health,
Год журнала:
2020,
Номер
5(4), С. 246 - 257
Опубликована: Июнь 9, 2020
Purpose:
Pubertal
suppression
is
standard
of
care
for
early
pubertal
transgender
youth
to
prevent
the
development
undesired
and
distressing
secondary
sex
characteristics
incongruent
with
gender
identity.
Preliminary
evidence
suggests
improves
mental
health
functioning.
Given
widespread
changes
in
brain
cognition
that
occur
during
puberty,
a
critical
question
whether
this
treatment
impacts
neurodevelopment.
Methods:
A
Delphi
consensus
procedure
engaged
24
international
experts
neurodevelopment,
development,
puberty/adolescence,
neuroendocrinology,
statistics/psychometrics
identify
priority
research
methodologies
address
empirical
question:
associated
real-world
neurocognitive
sequelae?
Recommended
study
approaches
reaching
80%
were
included
parameter.
Results:
The
identified
160
initial
expert
recommendations,
44
which
ultimately
achieved
consensus.
Consensus
design
elements
include
following:
minimum
three
measurement
time
points,
staging
at
baseline,
statistical
modeling
analyses,
use
analytic
account
heterogeneity,
multiple
comparison
groups
minimize
limitations
any
one
group.
untreated
matched
on
stage,
cisgender
(i.e.,
congruent)
an
independent
sample
from
large-scale
database.
domains
assessment
includes:
health,
executive
function/cognitive
control,
social
awareness/functioning.
Conclusion:
An
interdisciplinary
team
around
primary
methods
assessing
neurodevelopmental
effects
benefits
and/or
difficulties)
youth.
World Journal of Methodology,
Год журнала:
2021,
Номер
11(4), С. 116 - 129
Опубликована: Июль 19, 2021
The
Delphi
technique
is
a
systematic
process
of
forecasting
using
the
collective
opinion
panel
members.
structured
method
developing
consensus
among
members
methodology
has
gained
acceptance
in
diverse
fields
medicine.
methods
assumed
pivotal
role
last
few
decades
to
develop
best
practice
guidance
intelligence
where
research
limited,
ethically/logistically
difficult
or
evidence
conflicting.
However,
attempts
assess
quality
standard
studies
have
reported
significant
variance,
and
details
followed
are
usually
unclear.
We
recommend
tools
for
evaluation
methodology;
identification
problem
area
research,
selection
panel,
anonymity
panelists,
controlled
feedback,
iterative
rounds,
criteria,
analysis
consensus,
closing
stability
results.
Based
on
these
nine
qualitative
points,
we
assessed
medical
field
related
coronavirus
disease
2019.
There
was
inconsistency
reporting
vital
elements
such
as
members,
defining
criteria
presenting
propose
our
points
researchers,
journal
editorial
boards,
reviewers
evaluate
healthcare
research.
Universally,
the
volume
of
data
has
increased,
with
collection
rate
doubling
every
40
months,
since
1980s.
“Big
data”
is
a
term
that
was
introduced
in
1990s
to
include
sets
too
large
be
used
common
software.
Medicine
major
field
predicted
increase
use
big
2025.
Big
medicine
may
by
commercial,
academic,
government,
and
public
sectors.
It
includes
biologic,
biometric,
electronic
health
data.
Examples
biologic
biobanks;
biometric
have
individual
wellness
from
devices;
medical
record;
other
demographics
images.
also
contributed
changes
research
methodology.
Changes
clinical
paradigm
been
fueled
large-scale
biological
harvesting
(biobanks),
which
developed,
analyzed,
managed
cheaper
computing
technology
(big
data),
supported
greater
flexibility
study
design
(real-world
data)
relationships
between
industry,
government
regulators,
academics.
Cultural
along
easy
access
information
via
Internet
facilitate
ease
participation
more
people.
Current
needs
demand
quick
answers
supplied
data,
biobanks,
design.
can
reveal
patterns,
promises
provide
solutions
previously
out
society’s
grasp;
however,
murkiness
international
laws,
questions
ownership,
ignorance,
privacy
security
concerns
are
slowing
down
progress
could
otherwise
achieved
The
goal
this
descriptive
review
create
awareness
ramifications
for
encourage
readers
trend
positive
will
likely
lead
better
solutions,
but,
caution
must
exercised
reduce
harm.
BMJ Global Health,
Год журнала:
2021,
Номер
6(9), С. e006585 - e006585
Опубликована: Сен. 1, 2021
Background
Globally,
critical
illness
results
in
millions
of
deaths
every
year.
Although
many
these
are
potentially
preventable,
the
basic,
life-saving
care
critically
ill
patients
often
overlooked
health
systems.
Essential
Emergency
and
Critical
Care
(EECC)
has
been
devised
as
that
should
be
provided
to
all
hospitals
world.
EECC
includes
effective
low
cost
complexity
for
identification
treatment
across
medical
specialties.
This
study
aimed
specify
content
additionally,
given
surge
ongoing
pandemic,
essential
diagnosis-specific
with
COVID-19.
Methods
In
a
Delphi
process,
consensus
(>90%
agreement)
was
sought
from
diverse
panel
global
clinical
experts.
The
iteratively
rated
proposed
treatments
actions
based
on
previous
guidelines
WHO/ICRC’s
Basic
Care.
output
adapted
specialist
reviewers
into
coherent
feasible
package
processes
plus
list
hospital
readiness
requirements.
Results
269
experts
had
experience
different
acute
specialties
59
countries
resource
settings.
agreed
contains
40
67
requirements,
additions
specific
Conclusion
specified
patients.
Implementing
could
an
strategy
policy
makers
reduce
preventable
worldwide.
Nutrition Reviews,
Год журнала:
2020,
Номер
unknown
Опубликована: Март 31, 2020
Product
placement
strategies
have
been
used
to
influence
customers'
food
purchases
in
stores
for
some
time;
however,
assessment
of
the
evidence
that
these
techniques
can
limit
unhealthy,
and
promote
healthy,
choices
has
not
completed.
Archives of Physical Medicine and Rehabilitation,
Год журнала:
2020,
Номер
102(1), С. 76 - 86
Опубликована: Окт. 7, 2020
As
part
of
an
initiative
led
by
the
Brain
Injury
Special
Interest
Group
Mild
Traumatic
(TBI)
Task
Force
American
Congress
Rehabilitation
Medicine
(ACRM)
to
update
1993
ACRM
definition
mild
TBI,
present
study
aimed
characterize
current
expert
opinion
on
diagnostic
considerations.Cross-sectional
web-based
survey.Not
applicable.An
international,
interdisciplinary
group
clinician-scientists
(N=31)
with
expertise
in
TBI
completed
survey
invitation
between
May
and
July
2019
(100%
completion
rate).Not
applicable.Ratings
agreement
statements
related
diagnosis
ratings
importance
various
clinical
signs,
symptoms,
test
findings,
contextual
factors
for
increasing
likelihood
that
individual
sustained
a
scale
ranging
from
1
("not
at
all
important")
10
("extremely
important").Men
(n=25;
81%)
Americans
(n=21;
68%)
were
over-represented
sample.
The
revealed
areas
(eg,
acute
symptoms
are
diagnostically
useful)
disagreement
whether
abnormal
structural
neuroimaging
should
be
considered
same
entity
as
"concussion").
Observable
signs
generally
rated
more
important
than
subjective
(Wilcoxon
signed
ranks
test,
Z=3.77;
P<.001;
r=0.68).
Diagnostic
varied
widely,
some
common
postconcussion
fatigue)
unhelpful
(<75%
respondents
indicated
least
5
out
importance).
Certain
findings
cognitive
balance
impairments)
absence
confounds)
consistently
highly
(≥75%
7
10).The
identified
several
potential
revisions
consider
when
updating
definition,
including
preferentially
weighing
observable
probabilistic
framework,
incorporating
adding
differential
considerations.
Sustainability,
Год журнала:
2023,
Номер
15(14), С. 11277 - 11277
Опубликована: Июль 19, 2023
The
discipline
of
Landscape
Architecture
(LA)
is
currently
expanding
its
disciplinary
boundary.
supporting
Technology
in
LA
(TLA)
always
evolving
and
optimized
to
solve
environmental
problems.
Considering
the
uncertain
classification
current
knowledge
for
education
importance
technology
education,
a
refined
framework
needed.
This
research
first
established
Network
Model
(NMTLA)
using
Analysis
(NA)
expert
interviews.
Then,
this
proposed
an
Education
Framework
(EFLA)
based
on
NMTLA.
To
build
NMTLA,
identified
23
key
categories
TLA
through
content
analysis
secondary
research.
interview
network
theory
were
used
analyze
visualize
relationships
among
categories.
By
examining
degree
centrality,
closeness
betweenness
centrality
different
TLA,
study
developed
EFLA
which
summarizes
twenty-three
into
four
domains:
core
techniques,
applied
technologies,
integrated
specific
technologies.
also
proposes
series
suggestions
how
apply
today’s
future
education.
NMTLA
can
contribute
development
higher
They
potentially
address
Sustainable
Development
Goals
(SDGs)
industry.
However,
scope
limited
USA,
could
be
expanded
include
worldwide
perspective
enhance
validity
conclusions,
larger
sample
size
interviews
should
employed
further
studies.
Sustainable Production and Consumption,
Год журнала:
2024,
Номер
48, С. 460 - 480
Опубликована: Июнь 7, 2024
There
is
a
significant
deficiency
in
addressing
the
unique
characteristics
of
construction
and
demolition
waste
(C&DW)
United
Kingdom
(UK)
as
it
remains
primary
contributor
to
landfills.
Circular
economy
(CE)
practices
are
explored
address
this
risk
shortfall
management
comprehend
reduction
strategies
for
C&DW.
Using
Fuzzy
Delphi
approach,
study
maps
assesses
uncertainties
associated
with
identifying
indicators
ranked
CE
adoption
barriers
achieve
agreement
twelve
respondents.
Consensus
was
also
achieved
C&DW
measurement
indicators.
Concurrently,
eleven
separate
interviews
were
conducted
understand
CE's
effectiveness
improving
management.
The
results
indicated
that
most
barrier
inefficient
recycling
policies
ensure
high-quality
recycled
materials.
findings
underscore
influence
design,
managerial,
legal
surpasses
social,
knowledge,
culture.
Despite
highlighting
focus
on
recycling,
reusing,
reducing
raw
materials,
deeply
established
tendencies
prioritise
linear
economic
models
exist
widely,
resource
conservation
less
considered.
This
provides
concrete
implementation
responsible
consumption
production,
challenges
adoption,
offers
25
industry-specific
measuring
implementation.
World Psychiatry,
Год журнала:
2024,
Номер
23(1), С. 113 - 123
Опубликована: Янв. 12, 2024
Anxiety
disorders
are
very
prevalent
and
often
persistent
mental
disorders,
with
a
considerable
rate
of
treatment
resistance
which
requires
regulatory
clinical
trials
innovative
therapeutic
interventions.
However,
an
explicit
definition
treatment-resistant
anxiety
(TR-AD)
informing
such
is
currently
lacking.
We
used
Delphi
method-based
consensus
approach
to
provide
internationally
agreed,
consistent
clinically
useful
operational
criteria
for
TR-AD
in
adults.
Following
summary
the
current
state
knowledge
based
on
international
guidelines
available
systematic
review,
survey
free-text
responses
29-item
questionnaire
relevant
aspects
TR-AD,
online
meeting,
panel
36
multidisciplinary
experts
stakeholders
voted
anonymously
written
statements
three
rounds.
Consensus
was
defined
as
≥75%
agreeing
statement.
The
agreed
set
14
recommendations
providing
detailed
pharmacological
and/or
psychotherapeutic
treatment,
well
potential
staging
model.
also
evaluated
further
regarding
epidemiological
subgroups,
comorbidities
biographical
factors,
terminology
vs.
"difficult-to-treat"
preferences
attitudes
persons
these
future
research
directions.
This
expected
serve
systematic,
practical
guideline
aid
designing
mechanistic
studies
facilitate
purposes.
effort
could
ultimately
lead
development
more
effective
evidence-based
stepped-care
algorithms
patients
disorders.