A systematic review and meta-analysis of long term physical and mental sequelae of COVID-19 pandemic: call for research priority and action

Molecular Psychiatry, Год журнала: 2022, Номер 28(1), С. 423 - 433

Опубликована: Июнь 6, 2022

Язык: Английский

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A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action

Molecular Psychiatry, Год журнала: 2022, Номер 27(8), С. 3214 - 3222

Опубликована: Июнь 6, 2022

Язык: Английский

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The Psychology of Pandemics

Annual Review of Clinical Psychology, Год журнала: 2021, Номер 18(1), С. 581 - 609

Опубликована: Ноя. 15, 2021

This article reviews the current state of knowledge and promising new directions concerning psychology pandemics. Pandemics are disease outbreaks that spread globally. Historically, psychological factors have been neglected by researchers health authorities despite evidence pandemics are, to a large extent, phenomena whereby beliefs behaviors influence spreading versus containment infection. Psychological important in determining ( a) adherence pandemic mitigation methods (e.g., social distancing), b) pandemic-related disruption panic buying, racism, antilockdown protests), c) distress related problems anxiety, depression, posttraumatic stress disorder, prolonged grief disorder). The has emerged as an field research practice during coronavirus 2019 (COVID-19) pandemic. As scholarly discipline, is fragmented diverse, encompassing various subspecialties allied disciplines, but vital for shaping clinical public guidelines COVID-19 future

Язык: Английский

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Mental disorders following COVID-19 and other epidemics: a systematic review and meta-analysis

Translational Psychiatry, Год журнала: 2022, Номер 12(1)

Опубликована: Май 17, 2022

Abstract COVID-19 has imposed a very substantial direct threat to the physical health of those infected, although corollary impact on mental may be even more burdensome. Here we focus assessing and other epidemics in community. We searched five electronic databases until December 9, 2020, for all peer-reviewed original studies reporting any prevalence or correlates disorders general population following novel English, Chinese Portuguese. synthesised estimates from probability samples during past epidemics. The meta-analytical effect size was relevant outcomes, estimated via random-effects model. I 2 statistics, Doi plots LFK index were used examine heterogeneity publication bias. This study is pre-registered with PROSPERO, CRD42020179105. identified 255 eligible 50 countries on: ( n = 247 studies), severe acute respiratory syndrome (SARS; 5), Ebola virus disease 2), 1918 influenza 1). During COVID-19, point probable anxiety (20.7%, 95% CI 12.9–29.7), depression (18.1%, 13.0–23.9), psychological distress (13.0%, 0–34.1). Correlates poorer include female sex, lower income, pre-existing medical conditions, perceived risk infection, exhibiting COVID-19-like symptoms, social media use, financial stress, loneliness. Public trust authorities, availability accurate information, adoption preventive measures support associated less morbidity. consequences could comparable major disasters armed conflicts. considerable our analysis indicates that random are needed. Health-care professionals should vigilant toll epidemics, including among who have not been infected.

Язык: Английский

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A systematic review and meta-analysis on the prevalence of stigma in infectious diseases, including COVID-19: a call to action

Molecular Psychiatry, Год журнала: 2021, Номер 27(1), С. 19 - 33

Опубликована: Сен. 27, 2021

Infectious diseases, including COVID-19, are crucial public health issues and may lead to considerable fear among the general stigmatization of, discrimination against, specific populations. This meta-analysis aimed estimate pooled prevalence of stigma in infectious disease epidemics. We systematically searched PubMed, PsycINFO, Embase, MEDLINE, Web Science, Cochrane databases since inception June 08, 2021, reported towards people with diseases SARS, H1N1, MERS, Zika, Ebola, COVID-19. A total 50 eligible articles were included that contributed 51 estimates 92722 participants. The overall across all populations was 34% [95% CI: 28−40%], enacted (36% 28−44%]) perceived (31% 22−40%]). patients, community population, care workers, 38% 12− 65%], 36% 28−45%], 30% 20−40%], respectively. participants from low- middle-income countries 37% 29−45%], which is higher than high-income (27% 18−36%]) though this difference not statistically significant. similar trend also observed individuals lower education (47% 23−71%]) compared level (33% 23−4%]). These findings indicate a significant concern, effective comprehensive interventions needed counteract damaging effects infodemics during epidemics, reduce disease-related stigma.

Язык: Английский

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Global prevalence and associated risk factors of posttraumatic stress disorder during COVID-19 pandemic: A meta-analysis

International Journal of Nursing Studies, Год журнала: 2021, Номер 126, С. 104136 - 104136

Опубликована: Ноя. 11, 2021

Язык: Английский

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Mental and neurological disorders and risk of COVID-19 susceptibility, illness severity and mortality: A systematic review, meta-analysis and call for action

EClinicalMedicine, Год журнала: 2021, Номер 40, С. 101111 - 101111

Опубликована: Сен. 8, 2021

Coronavirus disease 2019 (COVID-19) has evolved into a worldwide pandemic, and been found to be closely associated with mental neurological disorders. We aimed comprehensively quantify the association between disorders, both pre-existing subsequent, risk of susceptibility, severity mortality COVID-19.In this systematic review meta-analysis, we searched PubMed, Web Science, Embase, PsycINFO, Cochrane library databases for studies published from inception up January 16, 2021 updated at July 7, 2021. Observational including cohort case-control, cross-sectional case series that reported estimates or disorders COVID-19 illness were included. Two researchers independently extracted data conducted quality assessment. Based on I2 heterogeneity, used random effects model calculate pooled odds ratios (OR) 95% confidence intervals (95% CI). Subgroup analyses meta-regression analysis also performed. This study was registered PROSPERO (registration number: CRD 42021230832).A total 149 (227,351,954 participants, 89,235,737 patients) included in analysis, which 27 morbidity (132,727,798), 56 (83,097,968) 115 (88,878,662). Overall, significant high infection (pre-existing mental: OR 1·67, CI 1·12-2·49; neurological: 2·05, 1·58-2·67), (mental: pre-existing, 1·40, 1·25-1·57; sequelae, 4·85, 2·53-9·32; 1·43, 1·09-1·88; 2·17, 1·45-3·24), 1·47, 1·26-1·72; 2·08, 1·61-2·69; 2·03, 1·66-2·49) COVID-19. revealed stronger among younger patients, those subsequent living low- middle-income regions. Younger patients higher than elders. For type-specific susceptibility contracting mood anxiety, attention-deficit hyperactivity disorder (ADHD); as well sleep disturbance; schizophrenia. dementia; delirium altered status; besides, dementia multiple specific diseases. Heterogeneities substantial across most analysis.The findings show an important role context provide clues directions identifying protecting vulnerable populations pandemic. Early detection intervention are urgently needed control induced by However, there heterogeneity studies, results should interpreted caution. More explore long-term sequela, underlying brain mechanisms sake elucidating causal pathways these associations.This is supported grants National Key Research Development Program China, Natural Science Foundation Special Fund PKUHSC Prevention Control COVID-19, Fundamental Funds Central Universities.

Язык: Английский

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Mechanisms of action of fluvoxamine for COVID-19: a historical review

Molecular Psychiatry, Год журнала: 2022, Номер 27(4), С. 1898 - 1907

Опубликована: Янв. 7, 2022

Язык: Английский

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Prevalence and risk factor for long COVID in children and adolescents: A meta-analysis and systematic review

Journal of Infection and Public Health, Год журнала: 2023, Номер 16(5), С. 660 - 672

Опубликована: Март 7, 2023

Millions of COVID-19 pediatric survivors are facing the risk long COVID after recovery from acute COVID-19. The primary objective this study was to systematically review available literature and determine pooled prevalence of, factors for among survivors.

Язык: Английский

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The prevalence of probable mental health disorders among hospital healthcare workers during COVID-19: A systematic review and meta-analysis

Journal of Affective Disorders, Год журнала: 2023, Номер 330, С. 329 - 345

Опубликована: Март 16, 2023

The mental health impacts of the COVID-19 pandemic continue to be documented worldwide with systematic reviews playing a pivotal role. Here we present updated findings from our review and meta-analysis on among hospital healthcare workers during COVID-19. We searched MEDLINE, CINAHL, PsycINFO, Embase Web Of Science Core Collection between 1st January 2000 17th February 2022 for studies using validated methods reporting prevalence diagnosed or probable disorders in pandemic. A proportions odds ratio was performed random effects model. Heterogeneity investigated test subgroup differences 95 % prediction intervals. included 401 studies, representing 458,754 participants across 58 countries. Pooled depression 28.5 (95 CI: 26.3–30.7), anxiety 28.7 26.5–31.0), PTSD 25.5 22.5–28.5), alcohol substance use disorder 25.3 13.3–39.6) insomnia 24.4 19.4–29.9). Prevalence rates were stratified by physicians, nurses, allied health, support staff students, which varied considerably. There significantly higher women, those working high-risk units providing direct care. Majority used self-report measures reflected rather than actual diagnosis. These have enhanced understanding at-risk groups hospitals. Targeted research towards these risks are recommended mitigate any long-term consequences.

Язык: Английский

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