Frontiers in Microbiology,
Год журнала:
2023,
Номер
14
Опубликована: Фев. 9, 2023
With
the
rapid
development
of
metagenomic
high-throughput
sequencing
technology,
more
and
oral
mucosal
diseases
have
been
proven
to
be
associated
with
microbiota
shifts
or
dysbiosis.
The
commensal
can
greatly
influence
colonization
resistance
pathogenic
microorganisms
induce
primary
immunity.
Once
dysbiosis
occurs,
it
lead
damage
epithelial
defense,
thus
accelerating
pathological
process.
As
common
diseases,
mucositis
ulcers
seriously
affect
patients'
prognosis
quality
life.
However,
from
perspective,
etiologies,
specific
alterations
flora,
changes,
therapy
for
are
still
lacking
in
a
comprehensive
overview.
This
review
makes
retrospective
summary
above
problems,
dialectically
based
on
microecology,
provide
new
perspective
lesions
management
aims
at
improving
Frontiers in Cellular and Infection Microbiology,
Год журнала:
2022,
Номер
12
Опубликована: Май 16, 2022
Several
strains
of
lactic
acid
bacteria
are
potent
probiotics
and
can
cure
a
variety
diseases
using
different
modes
actions.
These
produce
antimicrobial
peptides,
bacteriocins,
which
inhibit
or
kill
generally
closely
related
bacterial
other
pathogenic
such
as
Listeria,
Clostridium,
Salmonella.
Bacteriocins
cationic
peptides
that
the
target
cells
by
pore
formation
dissipation
cytosolic
contents,
leading
to
cell
death.
also
known
modulate
native
microbiota
host
immunity,
affecting
several
health-promoting
functions
host.
In
this
review,
we
have
discussed
ability
bacteriocin-producing
probiotic
in
modulation
gut
correcting
dysbiosis
treatment/maintenance
few
important
human
disorders
chronic
infections,
inflammatory
bowel
diseases,
obesity,
cancer.
Trends in Food Science & Technology,
Год журнала:
2023,
Номер
138, С. 178 - 198
Опубликована: Июнь 11, 2023
The
human
gut
hosts
complex
microbial
communities,
which
are
linked
to
health
and
disease.
microbiota
is
continuously
reshaped
by
multiple
environmental
factors,
especially
diet.
Gut
dysbiosis
may
promote
various
metabolic,
neurological,
intestinal,
cardiovascular
diseases,
even
tumor
development.
Probiotics
have
shown
promising
prophylactic,
mitigating,
or
curative
effects
when
use
as
nutrient
supplements
adjunctive
therapy.
These
beneficial
and/or
symptom
alleviation
often
accompanied
microbiome
metabolome
changes.
Differing
from
other
published
review
articles,
here
we
summarized
the
latest
knowledge
of
evidence-based
health-promoting
probiotics
scouring
literature
recent
animal
probiotic
intervention
studies.
To
elucidate
mechanisms
in
enhancing
intestinal
homeostasis,
barrier
function,
host
immunity,
through
modulating
its
metabolites.
Meanwhile,
also
discussed
challenges
data
analysis
clinical
research
comparison
between
laboratories,
provides
an
outlook
for
future
perspectives
applications
probiotics.
achieved
modulation.
Current
discussed.
Finally,
provided.
Colorectal
cancer
(CRC)
is
the
most
common
of
digestive
system
with
high
mortality
and
morbidity
rates.
Gut
microbiota
found
in
intestines,
especially
colorectum,
has
structured
crosstalk
interactions
host
that
affect
several
physiological
processes.
The
gut
include
CRC-promoting
bacterial
species,
such
as
Fusobacterium
nucleatum,
Escherichia
coli,
Bacteroides
fragilis,
CRC-protecting
Clostridium
butyricum,
Streptococcus
thermophilus,
Lacticaseibacillus
paracasei,
which
along
other
microorganisms,
viruses
fungi,
play
critical
roles
development
CRC.
Different
features
are
identified
patients
early-onset
CRC,
combined
different
patterns
between
fecal
intratumoral
microbiota.
may
be
beneficial
diagnosis
treatment
CRC;
some
bacteria
serve
biomarkers
while
others
regulators
chemotherapy
immunotherapy.
Furthermore,
metabolites
produced
by
essential
CRC
cells.
Harmful
primary
bile
acids
short-chain
fatty
acids,
whereas
others,
including
ursodeoxycholic
acid
butyrate,
impede
tumor
progression.
This
review
focuses
on
its
metabolites,
their
potential
development,
diagnosis,
Abstract
Elucidating
complex
interactions
between
bacteria
and
fungi
that
determine
microbial
community
structure,
composition,
functions
in
soil,
as
well
regulate
carbon
(C)
nutrient
fluxes,
is
crucial
to
understand
biogeochemical
cycles.
Among
the
various
interactions,
competition
for
resources
main
factor
determining
adaptation
niche
differentiation
these
two
big
groups
soil.
This
because
C
energy
limitations
growth
are
a
rule
rather
than
an
exception.
Here,
we
review
demands
of
fungi—the
major
kingdoms
soil—the
mechanisms
their
other
resources,
leading
differentiation,
global
change
impacts
on
this
competition.
The
normalized
utilization
preference
showed
1.4–5
times
more
efficient
uptake
simple
organic
compounds
substrates,
whereas
1.1–4.1
effective
utilizing
compounds.
Accordingly,
strongly
outcompete
while
take
advantage
Bacteria
also
compete
with
products
released
during
degradation
substrates.
Based
specifics,
differentiated
spatial,
temporal,
chemical
niches
will
increase
under
five
changes
including
elevated
CO2,
N
deposition,
soil
acidification,
warming,
drought.
Elevated
warming
bacterial
dominance,
acidification
drought
fungal
competitiveness.
