Selective Fluorosulfonylation of Thianthrenium Salts Enabled by Electrochemistry

Organic Letters, Год журнала: 2023, Номер 25(4), С. 581 - 586

Опубликована: Янв. 25, 2023

A practical electrochemically driven method for fluorosulfonylation of both aryl and alkyl thianthrenium salts has been disclosed. The strategy does not need external redox reagents or metal catalysts. In combination with C-H thianthrenation aromatics, this provides a new tool the site-selective drugs.

Язык: Английский

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Highly efficient construction of 2,3-disubstituted indoline derivatives by [4 + 1] annulation of sulfur ylides and o-sulfonamido aldimines

Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(6), С. 1521 - 1526

Опубликована: Янв. 1, 2023

A highly efficient [4 + 1] annulation of sulfur ylide salts and o -sulfonamido aldimines for construction valuable 2,3-disubstituted indolines is reported. It worth noting that indoles could also be synthesized by this cascade reaction.

Язык: Английский

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Asymmetric synthesis of spirofuro[2,3-b]azepine-5,3′-indoline derivativesviacycloisomerization/[4 + 3] annulation process under Au/N-heterocyclic carbene relay catalysis

Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(13), С. 3347 - 3352

Опубликована: Янв. 1, 2023

A variety of enantioenriched spirofuro[2,3- b ]azepine-5,3’-indoline derivatives were synthesized via Au(I)/chiral NHC relay catalyzed cycloisomerization/asymmetric [4+3] annulation.

Язык: Английский

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Visible-Light-Induced photoredox aerobic coupling of sulfonium ylides and amines leading to E-selective formation of 2-amino-2-butene-1,4-diones

Organic Chemistry Frontiers, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

A novel visible-light-induced photoredox three-component aerobic coupling reaction of sulfoxonium ylides and amines is reported.

Язык: Английский

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Synthesis of S-alkyl phosphorothioates/phosphorodithioates via ring-opening reaction of sulfonium salts with S₈, H-phosphonates or P₄S₁₀, and alcohols

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(20), С. 5731 - 5740

Опубликована: Янв. 1, 2024

A simple and practical method for the synthesis of S -alkyl phosphorothioates/phosphorodithioates through three-component reaction cyclic sulfonium salts with 8 , H -phosphonates, or P 4 10 alcohols was readily developed.

Язык: Английский

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Recent advance: Sulfur ylides in organic synthesis

Journal of Heterocyclic Chemistry, Год журнала: 2023, Номер 61(1), С. 29 - 70

Опубликована: Окт. 26, 2023

Abstract Sulfur ylides are versatile structures that display various characteristics and participate in a myriad of reactions to produce simple, effective, sometimes stereoselective toward synthesizing sulfur‐containing compounds. Nonetheless, their fulfillment tremendous developments have been made this field the past few decades. In comprehensive review, luminosity is illuminated on application sulfur involved domino, cascade annulation reactions, carbene trapping reagents with chameleonic reactivity. numerous decennary, chemists used solvent‐dependent, rhodium catalyzed, dealkylative intercepted, photochemical reaction, halotrifluoromethylation, benzannulation, amidation name such as Mizoroki–Heck, Suzuki–Miyaura, Sommelet–Hauser rearrangements. Moreover, other prime applications include metal catalysis, epoxidation carbonyl compounds, acylmethylation, cyclomerization, oxidation, insertion reactions. Additionally, some extremely useful play major role synthesis medicinally active heterocycles structural motifs. This review article discusses all these proposed mechanisms, current scenario, at length. tutorial concludes by providing future outlook investigation into compounds synthesized using it great potential be industries, laboratories, pharmaceutical companies, drug production, clinical use, medicinal chemistry, agrochemical purposes.

Язык: Английский

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Ring expansion of spirocyclopropanes with stabilized sulfonium ylides: highly diastereoselective synthesis of cyclobutanes

Chemical Communications, Год журнала: 2024, Номер 60(34), С. 4537 - 4540

Опубликована: Янв. 1, 2024

A novel method was devised for regioselective ring expansion of spirocyclopropanes to spirocyclobutanes with stabilized sulfonium ylides, affording 1,2- trans -disubstituted 6,8-dioxaspiro[3.5]nonane-5,9-diones without the formation any isomers.

Язык: Английский

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Research Advances in the Cyclization Reactions of Allylic Sulfonium Salts

Journal of Organic Chemistry Research, Год журнала: 2025, Номер 13(02), С. 77 - 86

Опубликована: Янв. 1, 2025

Язык: Английский

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Asymmetric construction of enantioenriched furo[2,3-b]pyridines through sequential gold, palladium/phosphoric acid catalysis

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(14), С. 3900 - 3905

Опубликована: Янв. 1, 2024

A multi-catalytic system combining gold, palladium and phosphoric acid was applied for asymmetric assembly of ynamides carbonate 4-hydroxy-2-cyclopentenone, furnishing furo[2,3- b ]pyridines in high yields stereoselectivities.

Язык: Английский

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Highly Diastereoselective One-Pot Synthesis of 4,5-Dihydrofuro[2,3-b]azocin-6-one Derivatives through Cyclization/[4+4] Annulation Reactions

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(11), С. 6704 - 6715

Опубликована: Май 8, 2023

A variety of 4,5-dihydrofuro[2,3-b]azocin-6-one derivatives were expediently assembled through Au(I)-catalyzed cyclization and 2-(tert-butyl)-1,1,3,3-tetramethylguanidine (BTMG)-mediated [4+4] annulation reactions enyne-amides ynones. The exhibit high efficiency with excellent regio- diastereoselectivity. broad spectrum substrates was utilized. products an eight-membered ring might be useful in biological chemistry medicinal science. Furthermore, the could facilely converted into various derivatives.

Язык: Английский

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