International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
25(1), С. 412 - 412
Опубликована: Дек. 28, 2023
The
presence
of
a
chiral
or
chirally
perturbed
chromophore
in
the
molecule
under
investigation
is
fundamental
requirement
for
appearance
circular
dichroism
(CD)
spectrum.
For
native
and
most
substituted
cyclodextrins,
this
condition
not
applicable,
because
although
chiral,
cyclodextrins
lack
group
therefore
have
no
characteristic
CD
spectra
over
220
nm.
reason
method
can
be
used
that
if
guest
has
right
proximity
to
cyclodextrin,
it
becomes
perturbed.
As
result,
complex
will
now
provide
signal,
phenomenon
called
induced
(ICD).
ICD
spectrum
clear
evidence
formation
complex,
spectral
sign
intensity
good
predictor
structure
complex.
By
varying
concentration
signal
changes,
resulting
saturation
curve,
from
these
data,
stability
constant
calculated
1:1
This
article
compares
NMR
spectroscopic
molecular
modeling
results
cyclodextrin
complexes
four
model
compounds:
nimesulide,
fenbufen,
fenoprofen,
bifonazole.
obtained
by
different
methods
show
agreement,
structures
estimated
are
supported
data
modeling.
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(8), С. 5470 - 5479
Опубликована: Фев. 14, 2024
Macrocycles
containing
chiral
organic
dyes
are
highly
valuable
for
the
development
of
supramolecular
circularly
polarized
luminescent
(CPL)
materials,
where
a
preorganized
framework
is
conducive
to
directing
π–π
self-assembly
and
delivering
strong
persistent
CPL
signal.
Here,
perylene
diimides
(PDIs)
an
excellent
choice
dye
component
because,
alongside
their
tunable
photophysical
properties,
functionalization
PDI's
core
yields
twisted,
π-system,
capable
CPL.
However,
configurationally
stable
PDI-based
macrocycles
rare,
those
that
also
beyond
dimers
unprecedented,
both
which
advantageous
robust
self-assembled
chiroptical
materials.
In
this
work,
we
report
first
bay-connected
bis-PDI
macrocycle
(ΔG⧧
>
155
kJ
mol–1).
We
use
chirally
locked
uncover
new
knowledge
PDI
perform
quantitative
imaging
resulting
single-crystal
As
such,
discover
chirality
1,7-disubstituted
provides
rational
route
designing
H-,
J-
concomitant
H-
J-type
important
arrangements
optimizing
(chir)optical
charge/energy
transport
properties.
Indeed,
reveal
amplified
in
single
crystals
our
by
quantifying
degree
emitted
light
circular
polarization
from
such
materials
time
using
CPL-Laser
Scanning
Confocal
Microscopy.
Journal of Separation Science,
Год журнала:
2024,
Номер
47(9-10)
Опубликована: Май 1, 2024
The
stereospecific
analysis
of
chiral
molecules
is
an
important
issue
in
many
scientific
fields.
In
separation
sciences,
this
achieved
via
the
formation
transient
diastereomeric
complexes
between
a
selector
and
selectand
enantiomers
driven
by
molecular
interactions
including
electrostatic,
ion‐dipole,
dipole‐dipole,
van
der
Waals
or
π‐π
as
well
hydrogen
halogen
bonds
depending
on
nature
selectand.
Nuclear
magnetic
resonance
spectroscopy
modeling
methods
are
currently
most
frequently
applied
techniques
to
understand
selector‐selectand
at
level
draw
conclusions
mechanism.
present
short
review
summarizes
some
recent
achievements
for
understanding
recognition
selectors
combining
with
and/or
spectroscopic
dating
2020
early
2024.
include
polysaccharide
derivatives,
cyclodextrins,
macrocyclic
glycopeptides,
proteins,
donor‐acceptor
type
selectors,
ion‐exchangers,
crown
ethers,
micelles.
application
ionic
liquids
deep
eutectic
solvents,
further
also
briefly
addressed.
A
compilation
all
published
literature
has
not
been
attempted.
Journal of Applied Polymer Science,
Год журнала:
2024,
Номер
141(30)
Опубликована: Май 9, 2024
Abstract
Polylactic
acid
has
good
biodegradability
and
processability,
but
its
flammability
serious
droplet
characteristics
limit
development
application.
Therefore,
developing
safer
flame‐retardant
PLA
materials
is
crucial.
This
research
develops
a
novel
polylactic
(PLA)
material
blend,
utilizing
aluminum
diethylphosphinate
(AlPi),
piperazine
pyrophosphate
(PAPP),
β‐cyclodextrin.
Optimal
synergy
occurs
at
5:1
PAPP/β‐CD
mass
ratio
with
4
wt.%
AlPi.
combination
significantly
reduces
the
heat
release
peak
from
294.89
to
144.21
kW·m
−2
generates
non‐combustible
residues.
The
sample
forms
stable,
uniform
carbon
layer
during
combustion
due
hydrogen
bond
crosslinking
Lewis
acid–base
reactions.
activation
energy
(Eα)
raised
264.99
281.08
kJ·mol
−1
between
312
402°C.
Thus,
an
AlPi‐PAPP‐β‐CD
based
P‐C‐N
composite
flame
retardant
investigated,
offering
promising
direction
for
fire‐safe
materials.
may
yield
valuable
insights
diverse
applications.
Analytical Methods,
Год журнала:
2024,
Номер
16(38), С. 6474 - 6486
Опубликована: Янв. 1, 2024
The
evaluation
of
surface-engineered
mono-
and
bimetallic
MOFs
in
enzyme-mimic
glucose
sensors
for
biomedical
applications
covers
recent
advancements
future
perspectives
their
nanocomposites.
A
sensitive
electrochemical
immunosensor
for
procymidone
detection
was
developed
based
on
a
supramolecular
amplification
strategy.
β-Cyclodextrin
(β-CD)-based
nanomaterials
were
employed
to
immobilize
ferrocene
derivative
(FC)-functionalized
antibodies/antigens
through
host-guest
interactions.
With
the
presence
of
procymidone,
formed
β-CD-labeled
bioconjugates
immobilized
antibody-modified
electrode
after
immunoreaction,
indicating
fabrication
immunosensor.
The
FC/β-CD
complexes
with
multiplex
electroactive
species
and
provided
more
sites
recognition
groups,
resulting
in
signal
sensor.
Monitored
differential
pulse
voltammetry,
proposed
exhibited
wide
linear
range
from
5
pM
0.1
μM
low
limit
(LOD)
1.67
pM.
as-prepared
possessed
high
sensitivity,
specificity,
stability
showed
great
potential
monitoring
field
food
safety.
IntechOpen eBooks,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 20, 2025
In
recent
years,
the
selective
adsorption
of
chiral
substances
has
attracted
considerable
research
attention
due
to
its
potential
applications
in
biomedicine.
This
process
involves
use
materials
capable
selectively
adsorbing
one
isomers,
which
opens
possibility
improve
drugs
and
create
new
diagnostic
therapeutic
methods.
Current
scientific
is
generally
focused
on
development
improvement
substances,
can
facilitate
more
precise
delivery
into
body,
minimizing
side
effects
improving
treatment
efficacy.
Thus,
molecules
represents
a
promising
direction
for
future
biomedical
technology
medicinal
chemistry.
this
overview,
chapter
examples
efficient
adsorbents
mechanisms
current
such
will
be
discussed.
