Oral Oncology Reports, Год журнала: 2024, Номер 10, С. 100273 - 100273
Опубликована: Март 13, 2024
• Label-free immunosensors enable personalized cancer treatments. High sensitivity allows label-free sensors to detect biomarkers. Eliminating the need of expensive labels makes these affordable. Immunosensors can simultaneously multiple Real-time monitoring aids in disease management and treatment efficacy.
Язык: Английский
TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 180, С. 117949 - 117949
Опубликована: Сен. 3, 2024
Язык: Английский
Процитировано
24
ACS Applied Nano Materials, Год журнала: 2025, Номер unknown
Опубликована: Янв. 10, 2025
Since their inception in the early 1960s, use of nanoscale materials has progressed leaps and bounds, role diverse fields ranging from human health to energy is undeniable. Nanosensors are devices having dimensions designed detect, record, transmit signals provide valuable data information. In this review, we utilize CAS Content Collection, a vast repository scientific information extracted journals patent publications, identify emerging applications field. This involves understanding trends, such as growth certain topics over time, well establishing relationships between topics. Our analysis indicates that among various nanomorphologies explored nanosensors, nanoparticles, nanotubes, quantum dots tend lead. terms types chemical biological sensors account for nearly 80% publications. combination with bibliographic data, utilized our access Registry identified host across substance classes (polymers, small molecules, elements) associated nanosensor Finally, major application nanosensors appears be biomedical nature (cancer diagnosis/testing drug discovery, example). findings highlighted TrendScape map provides an overview research interest concepts We also snapshot commercial development briefly discuss currently under development. It hope review comprehensive field serves guide researchers/scientists.
Язык: Английский
Процитировано
1
TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 172, С. 117569 - 117569
Опубликована: Янв. 30, 2024
Язык: Английский
Процитировано
8
Sensors, Год журнала: 2024, Номер 24(9), С. 2865 - 2865
Опубликована: Апрель 30, 2024
Glioblastoma, an aggressive primary brain tumor, poses a significant challenge owing to its dynamic and intricate tumor microenvironment. This review investigates the innovative integration of biosensor-enhanced organ-on-a-chip (OOC) models as novel strategy for in-depth exploration glioblastoma microenvironment dynamics. In recent years, transformative approach incorporating biosensors into OOC platforms has enabled real-time monitoring analysis cellular behaviors within controlled Conventional in vitro vivo exhibit inherent limitations accurately replicating complex nature progression. addresses existing research gap by pioneering models, providing comprehensive platform investigating The applications this combined studying dynamics are critically scrutinized, emphasizing potential bridge between simplistic conditions. Furthermore, article discusses implications elucidating features microenvironment, encompassing cell migration, proliferation, interactions. By furnishing insights, these significantly contribute unraveling biology glioblastoma, thereby influencing development more accurate diagnostic therapeutic strategies.
Язык: Английский
Процитировано
5
Journal of The Electrochemical Society, Год журнала: 2024, Номер 171(1), С. 017508 - 017508
Опубликована: Янв. 1, 2024
Depression is one of the most severe mental disorders, and facing challengeable lack objective diagnosis, as well early screening predicting treatment responses. Consequently, developing sensitive, efficient, convenient, accurate, real-time detection technology for depression markers earns more attention. Electrochemical immunosensor, a promising method analyzing disease markers, selectively binds target antigen with antibodies (Abs), converting biological signal antigen-antibody recognition reaction into an electrical related to concentration analyte. This has thrived in recent years areas such point-of-care (POC) diagnosis. article systematically reviews construction electrochemical immunosensors biomarkers over past 6 (2016–2022), including classification these sensors, commonly used electrode modification materials, optimization strategies. Finally, challenges future development clinical applications are prospected.
Язык: Английский
Процитировано
4
Crystal Growth & Design, Год журнала: 2025, Номер unknown
Опубликована: Март 13, 2025
Язык: Английский
Процитировано
0
Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 367 - 419
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Sensors and Actuators Reports, Год журнала: 2025, Номер unknown, С. 100316 - 100316
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Macromolecular Materials and Engineering, Год журнала: 2025, Номер unknown
Опубликована: Май 30, 2025
Abstract This study presents a hybrid modeling approach that integrates Kragelsky’s friction law and Archard’s wear with an artificial neural network (ANN) to predict the coefficient of (COF) specific rate (SWR) in epoxy‐based self‐lubricating composites reinforced graphite MoS₂. Given complex, nonlinear interactions among tribological parameters such as contact pressure, sliding speed, hardness, filler composition, traditional empirical models often fail capture behavior accurately. The proposed ANN architecture comprises input layer, three hidden layers employing sigmoid, ReLU, power activation functions, output layer predicting COF SWR. is trained using feed‐forward method backpropagation minimize prediction error. SEM analysis reveals imparts superior resistance compared achieved significantly higher accuracy for graphite‐reinforced composites. For COF, yielded MSE 0.00073 R ² 0.9047, while MoS₂ showed 0.00318 0.5567. SWR, attained 1.3351 0.9809, 1.6993 0.8271. reduced performance predictions attributed its oxidative degradation forming MoO₃. model also offers 3D surface simulations, aiding composite design optimization reducing experimental costs.
Язык: Английский
Процитировано
0
Electroanalysis, Год журнала: 2024, Номер 36(6)
Опубликована: Фев. 9, 2024
Abstract Electrochemistry has been one of the important tools in determining or evaluating vital conditions with help powerful and influential electrode designs. The fundamentals electrochemical determination are simply based on direct indirect electron transfer that occurs during process such as recognition target molecules by biorecognition elements. Therefore, biosensors have a significant development for promising analytical applications, particularly field biomedicine. In this context, immunosensors, which can detect biomarkers, provide many advantages their good performance practicability. Innovation immunosensors continues rapidly, non‐invasive wearable sensor technologies, especially personal equipment, come to fore. Developments nanotechnology easily be cited an driving force these advances. review, design technology used biomarker detection is briefly reviewed contribution nanoparticles efficiency examined basis future applications.
Язык: Английский
Процитировано
1