Label-free immunosensors for the ultrasensitive detection of cancer biomarkers DOI Creative Commons
Surendar Balu, Ashok K. Sundramoorthy

Oral Oncology Reports, Journal Year: 2024, Volume and Issue: 10, P. 100273 - 100273

Published: March 13, 2024

• Label-free immunosensors enable personalized cancer treatments. High sensitivity allows label-free sensors to detect biomarkers. Eliminating the need of expensive labels makes these affordable. Immunosensors can simultaneously multiple Real-time monitoring aids in disease management and treatment efficacy.

Language: Английский

Label-free electrochemical immunosensors: A practical guide DOI
Rocco Cancelliere, Elisa Paialunga, Asia Grattagliano

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 180, P. 117949 - 117949

Published: Sept. 3, 2024

Language: Английский

Citations

23
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment DOI
Weiyou Yang,

Tengyun Li,

Shufei Liao

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 172, P. 117569 - 117569

Published: Jan. 30, 2024

Language: Английский

Citations

7
Nanoscale Materials in Biomedical Applications of Sensors: Insights from a Comprehensive Landscape Analysis DOI Creative Commons
Kavita A. Iyer, Rumiana Koynova,

Krittika Ralhan

et al.

ACS Applied Nano Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 10, 2025

Since their inception in the early 1960s, use of nanoscale materials has progressed leaps and bounds, role diverse fields ranging from human health to energy is undeniable. Nanosensors are devices having dimensions designed detect, record, transmit signals provide valuable data information. In this review, we utilize CAS Content Collection, a vast repository scientific information extracted journals patent publications, identify emerging applications field. This involves understanding trends, such as growth certain topics over time, well establishing relationships between topics. Our analysis indicates that among various nanomorphologies explored nanosensors, nanoparticles, nanotubes, quantum dots tend lead. terms types chemical biological sensors account for nearly 80% publications. combination with bibliographic data, utilized our access Registry identified host across substance classes (polymers, small molecules, elements) associated nanosensor Finally, major application nanosensors appears be biomedical nature (cancer diagnosis/testing drug discovery, example). findings highlighted TrendScape map provides an overview research interest concepts We also snapshot commercial development briefly discuss currently under development. It hope review comprehensive field serves guide researchers/scientists.

Language: Английский

Citations

0
Nanocomposites used in biosensors DOI
Gomathi Sivakumar, Anashwara Babu, Samarendra Maji

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 367 - 419

Published: Jan. 1, 2025

Language: Английский

Citations

0
Various Methods of Synthesis and Applications of Gold-Based Nanomaterials: A Detailed Review DOI Creative Commons
Misbah Gul, Muhammad Kashif, Sheraz Muhammad

et al.

Crystal Growth & Design, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Language: Английский

Citations

0
Novel L-cysteine-functionalized Au@MnO2/MoO3 nanocomposites for electrochemical detection of apoptosis-related proteins in immunogenic cell death of patient-derived lung cancer cells DOI Creative Commons
Yi‐An Chen, Ming‐You Shie,

Kai Chang

et al.

Sensors and Actuators Reports, Journal Year: 2025, Volume and Issue: unknown, P. 100316 - 100316

Published: March 1, 2025

Language: Английский

Citations

0
Review—Electrochemical Immunosensors for Depression Markers Detection: Development in Recent Years DOI
Min Guo, Yan Chen,

Xiaohui Mo

et al.

Journal of The Electrochemical Society, Journal Year: 2024, Volume and Issue: 171(1), P. 017508 - 017508

Published: Jan. 1, 2024

Depression is one of the most severe mental disorders, and facing challengeable lack objective diagnosis, as well early screening predicting treatment responses. Consequently, developing sensitive, efficient, convenient, accurate, real-time detection technology for depression markers earns more attention. Electrochemical immunosensor, a promising method analyzing disease markers, selectively binds target antigen with antibodies (Abs), converting biological signal antigen-antibody recognition reaction into an electrical related to concentration analyte. This has thrived in recent years areas such point-of-care (POC) diagnosis. article systematically reviews construction electrochemical immunosensors biomarkers over past 6 (2016–2022), including classification these sensors, commonly used electrode modification materials, optimization strategies. Finally, challenges future development clinical applications are prospected.

Language: Английский

Citations

3
Biosensor-Enhanced Organ-on-a-Chip Models for Investigating Glioblastoma Tumor Microenvironment Dynamics DOI Creative Commons
Gayathree Thenuwara, Bilal Javed, Baljit Singh

et al.

Sensors, Journal Year: 2024, Volume and Issue: 24(9), P. 2865 - 2865

Published: April 30, 2024

Glioblastoma, an aggressive primary brain tumor, poses a significant challenge owing to its dynamic and intricate tumor microenvironment. This review investigates the innovative integration of biosensor-enhanced organ-on-a-chip (OOC) models as novel strategy for in-depth exploration glioblastoma microenvironment dynamics. In recent years, transformative approach incorporating biosensors into OOC platforms has enabled real-time monitoring analysis cellular behaviors within controlled Conventional in vitro vivo exhibit inherent limitations accurately replicating complex nature progression. addresses existing research gap by pioneering models, providing comprehensive platform investigating The applications this combined studying dynamics are critically scrutinized, emphasizing potential bridge between simplistic conditions. Furthermore, article discusses implications elucidating features microenvironment, encompassing cell migration, proliferation, interactions. By furnishing insights, these significantly contribute unraveling biology glioblastoma, thereby influencing development more accurate diagnostic therapeutic strategies.

Language: Английский

Citations

3
The role of nanoparticles in non‐invasive electrochemical immunosensor technology and recent developments DOI
Vildan Şanko, Cem Erkmen, Filiz Kuralay

et al.

Electroanalysis, Journal Year: 2024, Volume and Issue: 36(6)

Published: Feb. 9, 2024

Abstract Electrochemistry has been one of the important tools in determining or evaluating vital conditions with help powerful and influential electrode designs. The fundamentals electrochemical determination are simply based on direct indirect electron transfer that occurs during process such as recognition target molecules by biorecognition elements. Therefore, biosensors have a significant development for promising analytical applications, particularly field biomedicine. In this context, immunosensors, which can detect biomarkers, provide many advantages their good performance practicability. Innovation immunosensors continues rapidly, non‐invasive wearable sensor technologies, especially personal equipment, come to fore. Developments nanotechnology easily be cited an driving force these advances. review, design technology used biomarker detection is briefly reviewed contribution nanoparticles efficiency examined basis future applications.

Language: Английский

Citations

1
Label-free immunosensors for the ultrasensitive detection of cancer biomarkers DOI Creative Commons
Surendar Balu, Ashok K. Sundramoorthy

Oral Oncology Reports, Journal Year: 2024, Volume and Issue: 10, P. 100273 - 100273

Published: March 13, 2024

• Label-free immunosensors enable personalized cancer treatments. High sensitivity allows label-free sensors to detect biomarkers. Eliminating the need of expensive labels makes these affordable. Immunosensors can simultaneously multiple Real-time monitoring aids in disease management and treatment efficacy.

Language: Английский

Citations

1